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In chemistry, hydropersulfide refers to the functional group R-S-S-H. The anionic form of a hydropersulfide is a persulfide, analogous to the nomenclature for hydroperoxides. Persulfides are intermediates in the biosynthesis of iron-sulfur proteins and are invoked as precursors to hydrogen sulfide, a biological signaling molecule. Hydropersulfides are…
Biosynthetic and physiological roles, Structure and reactivity & Nomenclature
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hydropersulfides hydropersulfide sulfur persulfides via cysteine may hydrogen sulfide also transpersulfidation thiols protein cys disulfide formation species signaling persulfidation bond
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| N-ethylmaleimide.Because of the stability of the perthiyl radical | instance of | which is typically performed via alkylation of persulfides with electrophiles such as iodoacetamide derivatives and Michael acceptors | 0.80 | text |
| glutathione | instance of | oxidizes H2S to form hydropersulfides in the presence of a thiol acceptor | 0.80 | text |
| 4-thiouridine | instance of | which are used as sulfur sources for the biosynthesis of sulfur-containing cofactors | 0.80 | text |
| thiamine | instance of | which are used as sulfur sources for the biosynthesis of sulfur-containing cofactors | 0.80 | text |
| as well as iron-sulfur cluster assembly in both bacteria | instance of | which are used as sulfur sources for the biosynthesis of sulfur-containing cofactors | 0.80 | text |
| mammalian cells | instance of | which are used as sulfur sources for the biosynthesis of sulfur-containing cofactors | 0.80 | text |
| Persulfide | related to Biosynthetic and physiological roles | Hydropersulfides | 0.60 | section |
| Persulfide | related to Biosynthetic and physiological roles | Formation | 0.60 | section |
| Persulfide | related to Chemical properties | Hydropersulfides | 0.60 | section |
| Persulfide | related to Chemical properties | The S-H | 0.60 | section |
| Persulfide | related to Chemical properties | Thus | 0.60 | section |
| Persulfide | related to Chemical properties | However | 0.60 | section |
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