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PDCD1LG2

Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). PDCD1LG2 is an immune checkpoint receptor ligand which plays a role in negative regulation of the adaptive immune response. PD-L2 is one of two known…

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Aliases
PDCD1LG2, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2, programmed cell death 1 ligand 2
Band
9p24.1 · 19|19 C1
Bgee
stromal cell of endometrium · testicle · Achilles tendon · appendix · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 19 (mouse)
Databases
NCBI: entry; OMA: entry

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PDCD1LG2

Nodes60
Edges59
Triples83
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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PDCD1LG2

Top relations

Gene ontology · 21
PDCD1LG2 → adaptive immune response, cell surface, cell surface receptor signaling pathway, cellular response to lipopolysaccharide, endomembrane system, external side of plasma membrane, extracellular region, immune response, immune system process, integral component of membrane, membrane, molecular function, negative regulation of activated T cell proliferation, negative regulation of interferon-gamma production, negative regulation of interleukin-10 production, negative regulation of T cell proliferation, plasma membrane, positive regulation of T cell proliferation, protein binding, signal transduction
Bgee · 19
PDCD1LG2 → Achilles tendon, appendix, blood, embryo, gallbladder, gastrula, lumbar spinal ganglion, lymph node, mesenteric lymph nodes, right lung, skin of abdomen, smooth muscle tissue, spleen, stromal cell of endometrium, submandibular gland, testicle, thymus, tibiofemoral joint, upper lobe of left lung
RNA expression pattern · 19
PDCD1LG2 → Achilles tendon, appendix, blood, embryo, gallbladder, gastrula, lumbar spinal ganglion, lymph node, mesenteric lymph nodes, right lung, skin of abdomen, smooth muscle tissue, spleen, stromal cell of endometrium, submandibular gland, testicle, thymus, tibiofemoral joint, upper lobe of left lung
related to External links · 3
PDCD1LG2 → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
PDCD1LG2 → 19|19 C1, 9p24.1
Chr. · 2
PDCD1LG2 → Chromosome 19 (mouse), Chromosome 9 (human)
End · 2
PDCD1LG2 → 29,448,561 bp, 5,571,282 bp
Aliases · 1
PDCD1LG2 → PDCD1LG2, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2, programmed cell death 1 ligand 2
BioGPS · 1
PDCD1LG2 → More reference expression data
Databases · 1
PDCD1LG2 → NCBI: entry; OMA: entry

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Important terminology

pd-l2 cell pd-1 pd-l1 immune expression protein gene bp human chr band regulation chromosome receptor response programmed death ligand shown

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PDCD1LG2AliasesPDCD1LG2, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2, programmed cell death 1 ligand 21.00infobox
PDCD1LG2Band9p24.11.00infobox
PDCD1LG2Band19|19 C11.00infobox
PDCD1LG2Bgeestromal cell of endometrium1.00infobox
PDCD1LG2Bgeetesticle1.00infobox
PDCD1LG2BgeeAchilles tendon1.00infobox
PDCD1LG2Bgeeappendix1.00infobox
PDCD1LG2Bgeelymph node1.00infobox
PDCD1LG2Bgeespleen1.00infobox
PDCD1LG2Bgeegallbladder1.00infobox
PDCD1LG2Bgeesmooth muscle tissue1.00infobox
PDCD1LG2Bgeeupper lobe of left lung1.00infobox
PDCD1LG2Bgeeright lung1.00infobox
PDCD1LG2Bgeegastrula1.00infobox
PDCD1LG2Bgeeembryo1.00infobox
PDCD1LG2Bgeesubmandibular gland1.00infobox
PDCD1LG2Bgeethymus1.00infobox
PDCD1LG2Bgeemesenteric lymph nodes1.00infobox
PDCD1LG2Bgeelumbar spinal ganglion1.00infobox
PDCD1LG2Bgeetibiofemoral joint1.00infobox
PDCD1LG2Bgeeskin of abdomen1.00infobox
PDCD1LG2Bgeeblood1.00infobox
PDCD1LG2BioGPSMore reference expression data1.00infobox
PDCD1LG2Chr.Chromosome 9 (human)1.00infobox
PDCD1LG2Chr.Chromosome 19 (mouse)1.00infobox
PDCD1LG2DatabasesNCBI: entry; OMA: entry1.00infobox
PDCD1LG2End5,571,282 bp1.00infobox
PDCD1LG2End29,448,561 bp1.00infobox
PDCD1LG2EnsemblENSG000001976461.00infobox
PDCD1LG2Entrez803801.00infobox

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