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Substantia nigra

The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. Substantia nigra is Latin for "black substance", reflecting the fact that parts of the substantia nigra appear darker than neighboring areas due to high levels of neuromelanin in dopaminergic neurons. Parkinson's disease is…

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Acronym
SN
FMA
67947
Latin
substantia nigra
MeSH
D013378
NeuroLex ID
birnlex_789
NeuroNames
536

Topics to explore

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Overview

Structure

Pars reticulata

Function

Clinical significance

Chemical modification of the substantia nigra

History

Advanced semantic analysis

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Map overview Semantic statistics

Substantia nigra

Nodes110
Edges109
Triples142
Avg. degree1.98
Density0.018182
Components1

How this topic connects Entity context

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Substantia nigra

Top relations

related to Parkinson's disease · 11
Substantia nigra → Calbindin, For, However, Most, Other, Parkinson's, Parkinsonian, Regardless, Secondly, SNpc, The
related to MPTP · 10
Substantia nigra → California, In, MPPP, MPTP, No, Parkinson's, Parkinson's-like, Soon, The, Today
related to Schizophrenia · 10
Substantia nigra → Despite, Due, Dysbindin, However, In, Increased, Increased NMDA, NMDA, Other, These
related to Pars compacta · 9
Substantia nigra → D1, Dopaminergic, GABA, However, In, Lesions, Parkinson's, The, This
related to Pars reticulata · 9
Substantia nigra → Altered, GABAergic, However, Hz, In, Parkinson's, Projections, The, The GABAergic
related to Additional images · 8
Substantia nigra → Color, Dopamine, MRI, Neuromelanin MRI, Parkinson's, RGB, Substantia, T1
related to history · 8
Substantia nigra → Félix Vicq-d'Azyr, In, Oleh Hornykiewicz, Parkinson's, Samuel Thomas, Sano, Sömmerring, The
related to Structure · 8
Substantia nigra → GPi, Humans, It, SNpc, SNpr, Sometimes, The, The SN
related to Cocaine · 7
Substantia nigra → Cocaine, Cocaine's, DAT, However, In, Inactivation, The
related to External links · 5
Substantia nigra → Archived, BrainMaps, June, Stained, Wayback Machine

Important terminology Word statistics

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Important terminology

substantia pars nigra dopamine neurons compacta parkinson's dopaminergic reticulata disease striatum brain mptp basal ganglia symptoms cocaine movement schizophrenia nucleus

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Substantia nigraAcronymSN1.00infobox
Substantia nigraFMA679471.00infobox
Substantia nigraLatinsubstantia nigra1.00infobox
Substantia nigraMeSHD0133781.00infobox
Substantia nigraNeuroLex IDbirnlex_7891.00infobox
Substantia nigraNeuroNames5361.00infobox
Substantia nigraPart ofMidbrain, basal ganglia1.00infobox
Substantia nigraTA258811.00infobox
Substantia nigraTA98A14.1.06.1111.00infobox
Substantia nigrais aimportant player in brain function0.90text
Substantia nigrais aimportant processing center in the basal ganglia0.90text
Substantia nigrais atarget of chemical therapeutics for the treatment of Parkinson's disease0.90text

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    Min side: 3
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