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Polymyxin B

Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis, and urinary tract infections. While it is useful for many Gram negative infections, it is not useful for Gram positive infections. It can be given by injection into a vein, muscle, or cerebrospinal fluid or inhaled. The injectable…

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Overview

AntibioticMeningitisPneumoniaSepsisUrinary tract infections
25 related topics

Research application

Small RNA
1 related topics

Mechanism of action

Bacterial outer membraneCyclic peptideEndotoxin
3 related topics

Medical uses

Volemia
1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AHFS/Drugs.com
Monograph
ATC code
A07AA05 (WHO) J01XB02 (WHO) S01AA18 (WHO) S02AA11 (WHO) S03AA03 (WHO) QJ51XB02 (WHO)
CAS Number
1405-20-5 Y
ChEMBL
ChEMBL1201283 N
CompTox Dashboard (EPA)
DTXSID5045839
DrugBank
DB00781 N

Topics to explore

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Overview

Medical uses

Mechanism of action

Research application

Advanced semantic analysis

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Map overview Semantic statistics

Polymyxin B

Nodes35
Edges34
Triples17
Avg. degree1.94
Density0.057143
Components1

How this topic connects Entity context

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Polymyxin B

Top relations

AHFS/Drugs.com · 1
Polymyxin B → Monograph
ATC code · 1
Polymyxin B → A07AA05 (WHO) J01XB02 (WHO) S01AA18 (WHO) S02AA11 (WHO) S03AA03 (WHO) QJ51XB02 (WHO)
CAS Number · 1
Polymyxin B → 1405-20-5 Y
ChEMBL · 1
Polymyxin B → ChEMBL1201283 N
CompTox Dashboard (EPA) · 1
Polymyxin B → DTXSID5045839
DrugBank · 1
Polymyxin B → DB00781 N
ECHA InfoCard · 1
Polymyxin B → 100.014.340
Formula · 1
Polymyxin B → C56H100N16O17S
Legal status · 1
Polymyxin B → In general: Over-the-counter (OTC)
Molar mass · 1
Polymyxin B → 1301.57 g·mol−1

Important terminology Word statistics

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Important terminology

polymyxin used infections use muscle available bacterial cell medical neomycin endotoxin membrane given injection generally skin side effects include may

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Polymyxin BAHFS/Drugs.comMonograph1.00infobox
Polymyxin BATC codeA07AA05 (WHO) J01XB02 (WHO) S01AA18 (WHO) S02AA11 (WHO) S03AA03 (WHO) QJ51XB02 (WHO)1.00infobox
Polymyxin BCAS Number1405-20-5 Y1.00infobox
Polymyxin BChEMBLChEMBL1201283 N1.00infobox
Polymyxin BCompTox Dashboard (EPA)DTXSID50458391.00infobox
Polymyxin BDrugBankDB00781 N1.00infobox
Polymyxin BECHA InfoCard100.014.3401.00infobox
Polymyxin BFormulaC56H100N16O17S1.00infobox
Polymyxin BLegal statusIn general: Over-the-counter (OTC)1.00infobox
Polymyxin BMolar mass1301.57 g·mol−11.00infobox
Polymyxin BNIAID ChemDB0077971.00infobox
Polymyxin BPregnancy categoryB1.00infobox
Polymyxin BPubChem CID57021051.00infobox
Polymyxin BRoutes of administrationTopical, intramuscular, intravenous, intrathecal, eye drops1.00infobox
Polymyxin BTrade namesPoly-Rx, others1.00infobox
Polymyxin BUNII19371312D41.00infobox

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