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Nuclear receptor coactivator 2

The nuclear receptor coactivator 2 also known as NCoA-2 is a protein that in humans is encoded by the NCOA2 gene. NCoA-2 is also frequently called glucocorticoid receptor-interacting protein 1 (GRIP1), steroid receptor coactivator-2 (SRC-2), or transcriptional mediators/intermediary factor 2 (TIF2).

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Aliases
NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75, nuclear receptor coactivator 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GWQ, 1GWR, 1M2Z, 1MV9, 1MVC, 1MZN, 1P93, 1T63, 1T65, 1UHL, 1YOK, 1ZDT, 1ZDU, 1ZKY, 2AO6, 2B1V, 2B1Z, 2B23,…
Band
8q13.3 · 1 A3|1 4.12 cM
Bgee
corpus epididymis · endothelial cell · secondary oocyte · seminal vesicula · jejunal mucosa
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 1 (mouse)

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Overview

Function

Interactions

  • Interact Protein-protein interaction
  • AR Androgen receptor
  • ARNT Aryl hydrocarbon receptor nuclear translocator
  • BRCA1
  • ESR1 Estrogen receptor alpha
  • PPFIA4
  • RXRA Retinoid X receptor alpha
  • VDR Calcitriol receptor

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Map overview Semantic statistics

Nuclear receptor coactivator 2

Nodes20
Edges19
Triples119
Avg. degree1.9
Density0.1
Components1

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Nuclear receptor coactivator 2

Top relations

Gene ontology · 35
Nuclear receptor coactivator 2 → aryl hydrocarbon receptor binding, bile acid and bile salt transport, cellular response to hormone stimulus, cellular response to Thyroglobulin triiodothyronine, chromatin binding, circadian regulation of gene expression, circadian rhythm, cytoplasm, DNA-binding transcription factor activity, RNA polymerase II-specific, intracellular receptor signaling pathway, locomotor rhythm, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear body, nuclear receptor binding, nuclear receptor coactivator activity, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, protein binding
Bgee · 20
Nuclear receptor coactivator 2 → amniotic fluid, buccal mucosa cell, cerebellar vermis, ciliary body, corpus epididymis, endothelial cell, Epithelium of choroid plexus, habenula, jejunal mucosa, lacrimal gland, lateral geniculate nucleus, left lung lobe, lobe of cerebellum, median eminence, oral cavity, retinal pigment epithelium, secondary oocyte, seminal vesicula, substantia nigra, tibia
RNA expression pattern · 20
Nuclear receptor coactivator 2 → amniotic fluid, buccal mucosa cell, cerebellar vermis, ciliary body, corpus epididymis, endothelial cell, Epithelium of choroid plexus, habenula, jejunal mucosa, lacrimal gland, lateral geniculate nucleus, left lung lobe, lobe of cerebellum, median eminence, oral cavity, retinal pigment epithelium, secondary oocyte, seminal vesicula, substantia nigra, tibia
related to External links · 12
Nuclear receptor coactivator 2 → Human Nuclear, Medicine Medical Subject Headings, MeSH, Mouse Nuclear, National Library, NURSAC90Overview, Overview, PDB, PDBe-KB, Q15596, Q61026, UniProt
related to Interactions · 9
Nuclear receptor coactivator 2 → AR, ARNT, BRCA1, ESR1, NR3C1, Nuclear, PPFIA4, RXRA, VDR
Band · 2
Nuclear receptor coactivator 2 → 1 A3|1 4.12 cM, 8q13.3
Chr. · 2
Nuclear receptor coactivator 2 → Chromosome 1 (mouse), Chromosome 8 (human)
End · 2
Nuclear receptor coactivator 2 → 13,374,083 bp, 70,403,808 bp
Aliases · 1
Nuclear receptor coactivator 2 → NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75, nuclear receptor coactivator 2
Available structures · 1
Nuclear receptor coactivator 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GWQ, 1GWR, 1M2Z, 1MV9, 1MVC, 1MZN, 1P93, 1T63, 1T65, 1UHL, 1YOK, 1ZDT, 1ZDU, 1ZKY, 2AO6, 2B1V, 2B1Z, 2B23,…

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Important terminology

receptor nuclear coactivator bp ncoa2 human chr band protein gene ncoa-2 chromosome mouse dna grip1 factor location pdb uniprot transcriptional

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nuclear receptor coactivator 2AliasesNCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75, nuclear receptor coactivator 21.00infobox
Nuclear receptor coactivator 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1GWQ, 1GWR, 1M2Z, 1MV9, 1MVC, 1MZN, 1P93, 1T63, 1T65, 1UHL, 1YOK, 1ZDT, 1ZDU, 1ZKY, 2AO6, 2B1V, 2B1Z, 2B23,…1.00infobox
Nuclear receptor coactivator 2Band8q13.31.00infobox
Nuclear receptor coactivator 2Band1 A3|1 4.12 cM1.00infobox
Nuclear receptor coactivator 2Bgeecorpus epididymis1.00infobox
Nuclear receptor coactivator 2Bgeeendothelial cell1.00infobox
Nuclear receptor coactivator 2Bgeesecondary oocyte1.00infobox
Nuclear receptor coactivator 2Bgeeseminal vesicula1.00infobox
Nuclear receptor coactivator 2Bgeejejunal mucosa1.00infobox
Nuclear receptor coactivator 2Bgeeamniotic fluid1.00infobox
Nuclear receptor coactivator 2Bgeetibia1.00infobox
Nuclear receptor coactivator 2BgeeEpithelium of choroid plexus1.00infobox
Nuclear receptor coactivator 2Bgeebuccal mucosa cell1.00infobox
Nuclear receptor coactivator 2Bgeeoral cavity1.00infobox
Nuclear receptor coactivator 2Bgeesubstantia nigra1.00infobox
Nuclear receptor coactivator 2Bgeelacrimal gland1.00infobox
Nuclear receptor coactivator 2Bgeeciliary body1.00infobox
Nuclear receptor coactivator 2Bgeeleft lung lobe1.00infobox
Nuclear receptor coactivator 2Bgeeretinal pigment epithelium1.00infobox
Nuclear receptor coactivator 2Bgeelateral geniculate nucleus1.00infobox
Nuclear receptor coactivator 2Bgeehabenula1.00infobox
Nuclear receptor coactivator 2Bgeemedian eminence1.00infobox
Nuclear receptor coactivator 2Bgeelobe of cerebellum1.00infobox
Nuclear receptor coactivator 2Bgeecerebellar vermis1.00infobox
Nuclear receptor coactivator 2BioGPSMore reference expression data1.00infobox
Nuclear receptor coactivator 2Chr.Chromosome 8 (human)1.00infobox
Nuclear receptor coactivator 2Chr.Chromosome 1 (mouse)1.00infobox
Nuclear receptor coactivator 2DatabasesNCBI: entry; OMA: entry1.00infobox
Nuclear receptor coactivator 2End70,403,808 bp1.00infobox
Nuclear receptor coactivator 2End13,374,083 bp1.00infobox

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