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LIM and senescent cell antigen-like-containing domain protein 1 is a protein that in humans is encoded by the LIMS1 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around LIMS1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around LIMS1 shows recurring relationship patterns in the source. For example, LIMS1 → cell junction, cell junction assembly, cell-cell adhesion, cell-cell junction, cell-cell junction organization, cellular response to transforming growth factor beta stimulus, cytoplasm, cytosol, epithelial to mesenchymal transition, establishment of protein localization, focal adhesion, membrane, metal ion binding, negative regulation of transcription, DNA-templated, perinuclear region of cytoplasm, plasma membrane, positive regulation of cell-substrate adhesion, positive regulation of focal adhesion assembly, positive regulation of gene expression, positive regulation of GTPase activity Another extracted example is LIMS1 → ascending aorta, atrioventricular valve, atrium, cardiac muscle tissue of left ventricle, corneal stroma, decidua, Descending thoracic aorta, epithelium of colon, gastrocnemius muscle, genital tubercle, granulocyte, left lung lobe, monocyte, muscle of thigh, sciatic nerve, Skeletal muscle tissue of biceps brachii, soleus muscle, stromal cell of endometrium, tail of embryo, tail of epididymis. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp protein gene chr human band chromosome lim kinase cell location zinc mouse adhesion signaling domain function integrin-linked encoded search
TTTA extracted 95 structured relationships around LIMS1. Examples in this analysis include LIMS1 → Aliases → LIMS1, PINCH, PINCH-1, PINCH1, LIM zinc finger domain containing 1 and LIMS1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1G47, 1NYP, 1U5S, 2COR, 2D8X, 2KBX, 3F6Q, 4HI8, 4HI9. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| LIMS1 | Aliases | LIMS1, PINCH, PINCH-1, PINCH1, LIM zinc finger domain containing 1 | 1.00 | infobox |
| LIMS1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1G47, 1NYP, 1U5S, 2COR, 2D8X, 2KBX, 3F6Q, 4HI8, 4HI9 | 1.00 | infobox |
| LIMS1 | Band | 2q12.3 | 1.00 | infobox |
| LIMS1 | Band | 10 B4|10 29.31 cM | 1.00 | infobox |
| LIMS1 | Bgee | monocyte | 1.00 | infobox |
| LIMS1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| LIMS1 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| LIMS1 | Bgee | ascending aorta | 1.00 | infobox |
| LIMS1 | Bgee | muscle of thigh | 1.00 | infobox |
| LIMS1 | Bgee | decidua | 1.00 | infobox |
| LIMS1 | Bgee | tail of epididymis | 1.00 | infobox |
| LIMS1 | Bgee | Descending thoracic aorta | 1.00 | infobox |
| LIMS1 | Bgee | epithelium of colon | 1.00 | infobox |
| LIMS1 | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| LIMS1 | Bgee | granulocyte | 1.00 | infobox |
| LIMS1 | Bgee | left lung lobe | 1.00 | infobox |
| LIMS1 | Bgee | genital tubercle | 1.00 | infobox |
| LIMS1 | Bgee | cardiac muscle tissue of left ventricle | 1.00 | infobox |
| LIMS1 | Bgee | sciatic nerve | 1.00 | infobox |
| LIMS1 | Bgee | soleus muscle | 1.00 | infobox |
| LIMS1 | Bgee | atrioventricular valve | 1.00 | infobox |
| LIMS1 | Bgee | corneal stroma | 1.00 | infobox |
| LIMS1 | Bgee | atrium | 1.00 | infobox |
| LIMS1 | Bgee | tail of embryo | 1.00 | infobox |
| LIMS1 | BioGPS | n/a | 1.00 | infobox |
| LIMS1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| LIMS1 | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| LIMS1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| LIMS1 | End | 108,687,246 bp | 1.00 | infobox |
| LIMS1 | End | 58,260,513 bp | 1.00 | infobox |
The concept neighborhoods around LIMS1 bring nearby vocabulary together. In this analysis, examples include Function, Search and Zinc. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For LIMS1, one of the stronger structural bridges in this analysis connects LIMS1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around LIMS1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — LIMS1 · EN edition · Analysis: TopicsToTalkAbout
