Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Naltrexone: History, Community, Culture & Applications

Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use and opioid use disorders by reducing cravings and feelings of euphoria associated with substance use disorder. It has also been found to be effective for the treatment of other addictions and may be used for them off-label. The combination…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Naltrexone topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Naltrexone.

Related topics
226
Source areas
9
Connected nodes
235
Extracted relationships
219
Concept neighborhoods
46
Bridge connections
235

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 94 topics
Side effects · 45 topics
Medical uses · 34 topics
Chemistry · 13 topics
Research · 12 topics
Society and culture · 12 topics
History · 10 topics
Veterinary use · 4 topics
Overdose · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N07BB04 (WHO)
Bioavailability
5–60%
CAS Number
16590-41-3 Y
ChEBI
CHEBI:7465 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Overdose

Chemistry

History

Society and culture

Research

Veterinary use

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Naltrexone connects Entity context

The extracted context around Naltrexone shows recurring relationship patterns in the source. For example, Naltrexone → Alkermes, Bekhterev Research Psychoneurological Institute, Boston-based, Congressional, Critics, Despite, Evgeny Krupitsky, FDA, Further, In, July, Many, Medical University, Nearly, Norway, October, Russia, St Petersburg, St Petersburg State Pavlov, Subsequent Another extracted example is Naltrexone → Blumberg, Clinical, Dayton, Drug Abuse, DuPont, EN-1639A, Endo Laboratories, FDA, It, Metossian, National Institute, New York City, Revia, The, Trexan, Vivitrol, Wolf. Use these groups to spot repeated connection types before inspecting the individual relationships.

Naltrexone

Top relations

related to Controversies · 26
Naltrexone → Alkermes, Bekhterev Research Psychoneurological Institute, Boston-based, Congressional, Critics, Despite, Evgeny Krupitsky, FDA, Further, In, July, Many, Medical University, Nearly, Norway, October, Russia, St Petersburg, St Petersburg State Pavlov, Subsequent
related to history · 17
Naltrexone → Blumberg, Clinical, Dayton, Drug Abuse, DuPont, EN-1639A, Endo Laboratories, FDA, It, Metossian, National Institute, New York City, Revia, The, Trexan, Vivitrol, Wolf
related to Brand names · 16
Naltrexone → Adepend, Antaxone, Celupan, Contrave, Depade, Destoxican, Embeda, It, Nalorex, Narcoral, Nemexin, Nodict, Revia, Trexan, Vivitrex, Vivitrol
related to Others · 13
Naltrexone → Although, As, Case, Chantix, COVID, In, LDN, ME/CFS, October, Reports, The, Unlike, When
has effect · 11
Naltrexone → According, Another, Based, For, However, In, It, Most, The, These, Whether
related to Analogues · 8
Naltrexone → N-allylnorcodeine, N-allylnormorphine, N-allylnoroxymorphone, N-cyclobutylmethyl-14-hydroxydihydronormorphine, N-methylnaltrexone, Nalmefene, Other, The
related to Generic names · 8
Naltrexone → BANMTooltip British Approved Name, BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, INNTooltip International Nonproprietary Name, Name, USANTooltip United States Adopted, USPTooltip United States Pharmacopeia
related to Opioid use disorder · 8
Naltrexone → Among, In, Injection, It, Long-acting, OUD, Unlike, Vivitrol
related to Alcohol use disorder · 7
Naltrexone → Acamprosate, AUD, In, Its, John David Sinclair, Sinclair Method, Studies
Legal status · 6
Naltrexone → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

opioid effects studies may use opioids oral 6β-naltrexol buprenorphine alcohol mg treatment used brain administration antagonist dependence mor also withdrawal

Naltrexone relationships Subject–Predicate–Object triples

TTTA extracted 219 structured relationships around Naltrexone. Examples in this analysis include Naltrexone → 3D model (JSmol) → Interactive image and Naltrexone → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Naltrexone3D model (JSmol)Interactive image1.00infobox
NaltrexoneAHFS/Drugs.comMonograph1.00infobox
NaltrexoneATC codeN07BB04 (WHO)1.00infobox
NaltrexoneBioavailability5–60%1.00infobox
NaltrexoneCAS Number16590-41-3 Y1.00infobox
NaltrexoneChEBICHEBI:7465 Y1.00infobox
NaltrexoneChEMBLChEMBL19019 Y1.00infobox
NaltrexoneChemSpider4514524 Y1.00infobox
NaltrexoneCompTox Dashboard (EPA)DTXSID40463131.00infobox
NaltrexoneDrugBankDB00704 Y1.00infobox
NaltrexoneDuration of action>72 hours1.00infobox
NaltrexoneECHA InfoCard100.036.9391.00infobox
NaltrexoneElimination half-lifeOral (Revia): • Naltrexone: 4 hours • 6β-Naltrexol: 13 hours Oral (Contrave): • Naltrexone: 5 hours IMTooltip Intramuscular injection (Vivitrol): • Naltrexone: 5–10 days • 6β-Na…1.00infobox
NaltrexoneExcretionUrine1.00infobox
NaltrexoneFormulaC20H23NO41.00infobox
NaltrexoneIUPHAR/BPS16391.00infobox
NaltrexoneKEGGD05113 Y1.00infobox
NaltrexoneLegal statusAU: S4 (Prescription only)1.00infobox
NaltrexoneLegal statusBR: Class C1 (Other controlled substances)1.00infobox
NaltrexoneLegal statusCA: ℞-only1.00infobox
NaltrexoneLegal statusUK: POM (Prescription only)1.00infobox
NaltrexoneLegal statusUS: ℞-only1.00infobox
NaltrexoneLegal statusIn general: ℞ (Prescription only)1.00infobox
NaltrexoneLicense dataUS DailyMed: Naltrexone1.00infobox
NaltrexoneMedlinePlusa6850411.00infobox
NaltrexoneMelting point169 °C (336 °F)1.00infobox
NaltrexoneMetabolismLiver (non-CYP450)1.00infobox
NaltrexoneMetabolites6β-Naltrexol, others1.00infobox
NaltrexoneMolar mass341.407 g·mol−11.00infobox
NaltrexoneOnset of action30 minutes1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Naltrexone bring nearby vocabulary together. In this analysis, examples include Opioid, Effects and Studies. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Naltrexone
    • Opioid
    • Effects
    • Studies
    • Mg
    • 6β-naltrexol
    • Brain
    • Oral
    • Administration
    • Hours
    • Mor
    • Use
    • Alcohol
  • naltrexone
    • Opioid
    • Effects
    • Studies
    • Mg
    • 6β-naltrexol
    • Brain
    • Oral
    • Administration
    • Hours
    • Mor
    • Use
    • Alcohol
  • alcohol use
    • Brand
    • Name
    • Dependence
    • Disorder
    • Vivitrol
    • Use
    • Opioid
    • Studies
    • Effects
    • Treatment
    • Methadone
    • Opioids
  • opioid use disorders
    • Dependence
    • Receptors
    • Opioids
    • Antagonist
    • Receptor
    • Treatment
    • Opioid
    • Use
    • May
    • Methadone
    • Vivitrol
    • Withdrawal
  • substance use disorder
    • Use
    • Name
    • Treatment
    • Opioid
    • Overdose
    • Vivitrol
    • Methadone
    • Used
    • Opioids
    • Buprenorphine
    • Elimination
    • Studies
  • naltrexone/bupropion
    • Opioid
    • Effects
    • Studies
    • Mg
    • 6β-naltrexol
    • Brain
    • Oral
    • Administration
    • Hours
    • Mor
    • Use
    • Alcohol
  • blocks the effects
    • Naltrexone
    • Studies
    • Opioids
    • Blockade
    • Opioid
    • Receptor
    • Hours
    • Found
    • Mg
    • May
    • Dependence
    • Name
  • opioids naturally produced in the brain
    • Mor
    • Dose
    • Hours
    • Mg
    • Blockade
    • Found
    • Naltrexone
    • Use
    • Withdrawal
    • Receptor
    • Receptors
    • Opioid

Connections between topic areas Semantic bridges

For Naltrexone, one of the stronger structural bridges in this analysis connects Naltrexone with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NaltrexoneOverview · splits 141 ⟂ 95
NaltrexoneSide effects · splits 190 ⟂ 46
NaltrexoneMedical uses · splits 201 ⟂ 35
NaltrexoneChemistry · splits 222 ⟂ 14
NaltrexoneSociety and culture · splits 223 ⟂ 13
NaltrexoneResearch · splits 223 ⟂ 13
NaltrexoneHistory · splits 225 ⟂ 11
NaltrexoneVeterinary use · splits 231 ⟂ 5
NaltrexoneOverdose · splits 233 ⟂ 3

Map overview Semantic statistics

Naltrexone

Nodes236
Edges235
Triples219
Avg. degree1.99
Density0.008475
Components1

Source & methodology

TTTA analyzes the structure around Naltrexone to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Naltrexone · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.