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John David Sinclair

John David Sinclair (March 28, 1943 – April 6, 2015) was an American scientist and researcher best known for discovering the Alcohol Deprivation Effect (ADE) and targeted pharmacological extinction, otherwise known as the Sinclair Method, as a medication treatment for Alcohol Use Disorder (AUD).

Works, Career, Standards & Science

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Topic orientation

John David Sinclair at a glance

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Key facts & relationships

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Known for
The Sinclair Method, Pharmacological extinction
Born
(1943-03-28)March 28, 1943 Bluefield, West Virginia, U.S.
Children
Stephanie Sinclair Lappi, Joanna Sinclair, Pamela Sinclair, Annette Sinclair
Died
April 6, 2015(2015-04-06) (aged 72) Evitskog, Finland
Occupations
Scientist · researcher

Topics to explore

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Overview

Early life

Education

Career

Advanced semantic analysis

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How this topic connects Entity context

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John David Sinclair

Top relations

Occupations · 2
John David Sinclair → researcher, Scientist
Born · 1
John David Sinclair → (1943-03-28)March 28, 1943 Bluefield, West Virginia, U.S.
Children · 1
John David Sinclair → Stephanie Sinclair Lappi, Joanna Sinclair, Pamela Sinclair, Annette Sinclair
Died · 1
John David Sinclair → April 6, 2015(2015-04-06) (aged 72) Evitskog, Finland
Known for · 1
John David Sinclair → The Sinclair Method, Pharmacological extinction
Spouse · 1
John David Sinclair → .mw-parser-output .marriage-line-margin2px{line-height:0;margin-bottom:-2px}.mw-parser-output .marriage-line-margin3px{line-height:0;margin-bottom:-3px}.mw-parser-output .marria…

Important terminology Word statistics

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Important terminology

sinclair alcohol method extinction pharmacological university research treatment use disorder drinking deprivation ade 2015 scientist researcher known oregon science opioid

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
John David SinclairBorn(1943-03-28)March 28, 1943 Bluefield, West Virginia, U.S.1.00infobox
John David SinclairChildrenStephanie Sinclair Lappi, Joanna Sinclair, Pamela Sinclair, Annette Sinclair1.00infobox
John David SinclairDiedApril 6, 2015(2015-04-06) (aged 72) Evitskog, Finland1.00infobox
John David SinclairKnown forThe Sinclair Method, Pharmacological extinction1.00infobox
John David SinclairOccupationsScientist1.00infobox
John David SinclairOccupationsresearcher1.00infobox
John David SinclairSpouse.mw-parser-output .marriage-line-margin2px{line-height:0;margin-bottom:-2px}.mw-parser-output .marriage-line-margin3px{line-height:0;margin-bottom:-3px}.mw-parser-output .marria…1.00infobox
naltrexone or nalmefene reduces the reinforcement such that a person is no longer interested in alcohol.This solutioninstance ofTaking an opioid antagonist0.80text
pharmacological extinctioninstance ofTaking an opioid antagonist0.80text
became apparent when he wrote The Rest Principleinstance ofTaking an opioid antagonist0.80text

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    Connections between topic areas Semantic bridges

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    Map overview Semantic statistics

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    John David Sinclair

    Nodes33
    Edges32
    Triples10
    Avg. degree1.94
    Density0.060606
    Components1
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