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Nalmefene: Applications & Research

Nalmefene, sold under the brand name Revex among others, is a medication that is used in the treatment of opioid overdose and alcohol dependence. Nalmefene belongs to the class of opioid antagonists and can be taken by mouth, administered by injection, or delivered through nasal administration.

Language: English [EN]
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Nalmefene topic overview

The analysis highlights Applications and Research as prominent areas in the source structure around Nalmefene.

Related topics
60
Source areas
4
Connected nodes
64
Extracted relationships
55
Concept neighborhoods
22
Bridge connections
64

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 46 topics
Research · 10 topics
Medical uses · 2 topics
Pharmacology · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N07BB05 (WHO)
Bioavailability
40–50% (orally)
CAS Number
55096-26-9 Y · as HCl: 58895-64-0
ChEBI
CHEBI:7457

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Pharmacology

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Nalmefene connects Entity context

The extracted context around Nalmefene shows recurring relationship patterns in the source. For example, Nalmefene → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only Another extracted example is Nalmefene → Based, European Union, NICE, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Nalmefene

Top relations

Legal status · 4
Nalmefene → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Alcohol dependence · 4
Nalmefene → Based, European Union, NICE, The
related to Metabolism · 4
Nalmefene → Less, N-dealkylated, N-dealkylation, The
related to Common · 3
Nalmefene → Decreased, SomnolenceTremorDisturbance, The
CAS Number · 2
Nalmefene → 55096-26-9 Y, as HCl: 58895-64-0
ChEMBL · 2
Nalmefene → as HCl: ChEMBL1201152, ChEMBL982 Y
ChemSpider · 2
Nalmefene → 4447642 Y, as HCl: 4534959
DrugBank · 2
Nalmefene → as HCl: DBSALT001446, DB06230
KEGG · 2
Nalmefene → as HCl: D02104, D05111
UNII · 2
Nalmefene → as HCl: K7K69QC05X, TOV02TDP9I

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

alcohol opioid treatment mor dependence naltrexone medication overdose kor brain hours administration mouth antagonist receptor intravenous also name affinity people

Nalmefene relationships Subject–Predicate–Object triples

TTTA extracted 55 structured relationships around Nalmefene. Examples in this analysis include Nalmefene → 3D model (JSmol) → Interactive image and Nalmefene → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Nalmefene3D model (JSmol)Interactive image1.00infobox
NalmefeneAHFS/Drugs.comMonograph1.00infobox
NalmefeneATC codeN07BB05 (WHO)1.00infobox
NalmefeneBioavailability40–50% (orally)1.00infobox
NalmefeneCAS Number55096-26-9 Y1.00infobox
NalmefeneCAS Numberas HCl: 58895-64-01.00infobox
NalmefeneChEBICHEBI:74571.00infobox
NalmefeneChEMBLChEMBL982 Y1.00infobox
NalmefeneChEMBLas HCl: ChEMBL12011521.00infobox
NalmefeneChemSpider4447642 Y1.00infobox
NalmefeneChemSpideras HCl: 45349591.00infobox
NalmefeneCompTox Dashboard (EPA)DTXSID80233471.00infobox
NalmefeneDrug classOpioid antagonist; κ-Opioid receptor agonist1.00infobox
NalmefeneDrugBankDB062301.00infobox
NalmefeneDrugBankas HCl: DBSALT0014461.00infobox
NalmefeneECHA InfoCard100.164.9481.00infobox
NalmefeneElimination half-life10.8 ± 5.2 hours1.00infobox
NalmefeneExcretionKidney1.00infobox
NalmefeneFormulaC21H25NO31.00infobox
NalmefeneIUPHAR/BPS16281.00infobox
NalmefeneKEGGD051111.00infobox
NalmefeneKEGGas HCl: D021041.00infobox
NalmefeneLegal statusAU: S4 (Prescription only)1.00infobox
NalmefeneLegal statusUK: POM (Prescription only)1.00infobox
NalmefeneLegal statusUS: ℞-only1.00infobox
NalmefeneLegal statusEU: Rx-only1.00infobox
NalmefeneLicense dataUS DailyMed: Nalmefene1.00infobox
NalmefeneMedlinePlusa6050431.00infobox
NalmefeneMetabolismLiver1.00infobox
NalmefeneMolar mass339.435 g·mol−11.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Nalmefene bring nearby vocabulary together. In this analysis, examples include Treatment, Alcohol and Dependence. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Nalmefene
    • Treatment
    • Alcohol
    • Dependence
    • Opioid
    • Mor
    • Administration
    • Overdose
    • People
    • Brain
    • Kor
    • Also
    • Approved
  • nalmefene
    • Treatment
    • Alcohol
    • Dependence
    • Opioid
    • Mor
    • Administration
    • Overdose
    • People
    • Brain
    • Kor
    • Also
    • Approved
  • opioid overdose
    • Overdose
    • Approved
    • Antagonist
    • Revex
    • Administration
    • Fda
    • States
    • United
    • People
    • Treatment
    • Mouth
    • Receptor
  • alcohol dependence
    • Dependence
    • Used
    • Treatment
    • People
    • Medication
    • European
    • Nalmefene
    • Revex
    • Name
    • States
    • United
    • Use
  • opioid antagonists
    • Overdose
    • Antagonist
    • Administration
    • Approved
    • Revex
    • Fda
    • Mouth
    • Receptor
    • States
    • Treatment
    • United
    • People
  • oral administration
    • Injection
    • Intravenous
    • Opioid
    • Mouth
    • Name
    • Overdose
    • Hours
    • Treatment
    • Nalmefene
    • Blockade
    • Brand
    • Effects
  • food and drug administration
    • Injection
    • Intravenous
    • Opioid
    • Mouth
    • Name
    • Overdose
    • Hours
    • Treatment
    • Nalmefene
    • Blockade
    • Brand
    • Effects
  • alcohol
    • Dependence
    • Used
    • People
    • Treatment
    • Medication
    • Nalmefene
    • European
    • Revex
    • Name
    • States
    • United
    • Use

Connections between topic areas Semantic bridges

For Nalmefene, one of the stronger structural bridges in this analysis connects Nalmefene with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Nalmefene — Overview · splits 18 ⟂ 47
Nalmefene — Research · splits 54 ⟂ 11
Nalmefene — Medical uses · splits 62 ⟂ 3
Nalmefene — Pharmacology · splits 62 ⟂ 3

Map overview Semantic statistics

Nalmefene

Nodes65
Edges64
Triples55
Avg. degree1.97
Density0.030769
Components1

Source & methodology

TTTA analyzes the structure around Nalmefene to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Nalmefene · EN edition · Analysis: TopicsToTalkAbout

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