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Nalmefene

Nalmefene, sold under the brand name Revex among others, is a medication that is used in the treatment of opioid overdose and alcohol dependence. Nalmefene belongs to the class of opioid antagonists and can be taken by mouth, administered by injection, or delivered through nasal administration.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N07BB05 (WHO)
Bioavailability
40–50% (orally)
CAS Number
55096-26-9 Y · as HCl: 58895-64-0
ChEBI
CHEBI:7457

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Overview

Medical uses

Pharmacology

Research

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Map overview Semantic statistics

Nalmefene

Nodes65
Edges64
Triples55
Avg. degree1.97
Density0.030769
Components1

How this topic connects Entity context

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Nalmefene

Top relations

Legal status · 4
Nalmefene → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Alcohol dependence · 4
Nalmefene → Based, European Union, NICE, The
related to Metabolism · 4
Nalmefene → Less, N-dealkylated, N-dealkylation, The
related to Common · 3
Nalmefene → Decreased, SomnolenceTremorDisturbance, The
CAS Number · 2
Nalmefene → 55096-26-9 Y, as HCl: 58895-64-0
ChEMBL · 2
Nalmefene → as HCl: ChEMBL1201152, ChEMBL982 Y
ChemSpider · 2
Nalmefene → 4447642 Y, as HCl: 4534959
DrugBank · 2
Nalmefene → as HCl: DBSALT001446, DB06230
KEGG · 2
Nalmefene → as HCl: D02104, D05111
UNII · 2
Nalmefene → as HCl: K7K69QC05X, TOV02TDP9I

Important terminology Word statistics

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Important terminology

alcohol opioid treatment mor dependence naltrexone medication overdose kor brain hours administration mouth antagonist receptor intravenous also name affinity people

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nalmefene3D model (JSmol)Interactive image1.00infobox
NalmefeneAHFS/Drugs.comMonograph1.00infobox
NalmefeneATC codeN07BB05 (WHO)1.00infobox
NalmefeneBioavailability40–50% (orally)1.00infobox
NalmefeneCAS Number55096-26-9 Y1.00infobox
NalmefeneCAS Numberas HCl: 58895-64-01.00infobox
NalmefeneChEBICHEBI:74571.00infobox
NalmefeneChEMBLChEMBL982 Y1.00infobox
NalmefeneChEMBLas HCl: ChEMBL12011521.00infobox
NalmefeneChemSpider4447642 Y1.00infobox
NalmefeneChemSpideras HCl: 45349591.00infobox
NalmefeneCompTox Dashboard (EPA)DTXSID80233471.00infobox
NalmefeneDrug classOpioid antagonist; κ-Opioid receptor agonist1.00infobox
NalmefeneDrugBankDB062301.00infobox
NalmefeneDrugBankas HCl: DBSALT0014461.00infobox
NalmefeneECHA InfoCard100.164.9481.00infobox
NalmefeneElimination half-life10.8 ± 5.2 hours1.00infobox
NalmefeneExcretionKidney1.00infobox
NalmefeneFormulaC21H25NO31.00infobox
NalmefeneIUPHAR/BPS16281.00infobox
NalmefeneKEGGD051111.00infobox
NalmefeneKEGGas HCl: D021041.00infobox
NalmefeneLegal statusAU: S4 (Prescription only)1.00infobox
NalmefeneLegal statusUK: POM (Prescription only)1.00infobox
NalmefeneLegal statusUS: ℞-only1.00infobox
NalmefeneLegal statusEU: Rx-only1.00infobox
NalmefeneLicense dataUS DailyMed: Nalmefene1.00infobox
NalmefeneMedlinePlusa6050431.00infobox
NalmefeneMetabolismLiver1.00infobox
NalmefeneMolar mass339.435 g·mol−11.00infobox

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