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SOX9

Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene.

Function, Clinical significance & Interactions

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Explore the main themes, entities and connections around SOX9. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

27 related topics

Clinical significance

8 related topics

Interactions

6 related topics

Role in sexual differentiation

4 related topics

Key facts & relationships

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Aliases
SOX9, CMD1, CMPD1, SRA1, SRXX2, SRXY10, SRY-box 9, SRY-box transcription factor 9
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4EUW
Band
17q24.3 · 11 E2|11 77.27 cM
Bgee
ventricular zone · hair follicle · optic nerve · parotid gland · retinal pigment epithelium
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Topics to explore

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Overview

Function

Clinical significance

Role in sexual differentiation

Interactions

Knock out models

Advanced semantic analysis

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Map overview Semantic statistics

SOX9

Nodes56
Edges55
Triples288
Avg. degree1.96
Density0.035714
Components1

How this topic connects Entity context

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SOX9

Top relations

Gene ontology · 157
SOX9 → anterior head development, aortic valve morphogenesis, astrocyte fate commitment, beta-catenin binding, bHLH transcription factor binding, branching involved in ureteric bud morphogenesis, bronchus cartilage development, cAMP-mediated signaling, cartilage condensation, cartilage development, cell differentiation, cell fate commitment, cell fate specification, cell-cell adhesion, cellular response to BMP stimulus, cellular response to epidermal growth factor stimulus, cellular response to heparin, cellular response to interleukin-1, cellular response to mechanical stimulus, cellular response to retinoic acid
Bgee · 20
SOX9 → basisphenoid, buccal mucosa cell, cartilage organ, cartilage tissue, cervical loop, digit, epithelium of seminiferous tubule of testis, hair follicle, internal globus pallidus, lacrimal gland, lactiferous duct, main bronchus, optic nerve, parotid gland, pylorus, retinal pigment epithelium, second toe, sphenoid bone, toe, ventricular zone
RNA expression pattern · 20
SOX9 → basisphenoid, buccal mucosa cell, cartilage organ, cartilage tissue, cervical loop, digit, epithelium of seminiferous tubule of testis, hair follicle, internal globus pallidus, lacrimal gland, lactiferous duct, main bronchus, optic nerve, parotid gland, pylorus, retinal pigment epithelium, second toe, sphenoid bone, toe, ventricular zone
related to Function · 20
SOX9 → Activation, AMH, CCTTGAG, Dax1, DNA-binding, FGF9, HMG-box, In, It, Müllerian, Next, PGD2, Sertoli, Sf1, SOX-9, SRY, The, These, Wwp1, Wwp2
related to External links · 16
SOX9 → Human Transcription, Medicine, Medicine Medical Subject Headings, MeSH, Mouse Transcription, National Library, Overview, P48436, PDB, PDBe-KB, Q04887, SOX-9, This, UCSC Genome Browser, UniProt, United States National Library
related to Role in sexual differentiation · 10
SOX9 → DAX1, If FGF9, Mutation, Mutations, Sertoli, SRY, The, X-chromosome, XX, XY
related to Knock out models · 7
SOX9 → CD, CSPG, CSPGs, Loss, NOGO, There, These Sox9
related to Interactions · 5
SOX9 → MAF, MED12, MLL3, MLL4, SWI/SNF
related to Clinical significance · 4
SOX9 → Deletions, Mb, Mutations, Pierre Robin Sequence
related to SOX9 localization and dynamics · 3
SOX9 → DNA, Its, Studies

Important terminology Word statistics

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Important terminology

gene sox-9 transcription factor sry human development cells bp testis male protein chr band differentiation chromosome also sertoli fgf9 17

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SOX9AliasesSOX9, CMD1, CMPD1, SRA1, SRXX2, SRXY10, SRY-box 9, SRY-box transcription factor 91.00infobox
SOX9Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4EUW1.00infobox
SOX9Band17q24.31.00infobox
SOX9Band11 E2|11 77.27 cM1.00infobox
SOX9Bgeeventricular zone1.00infobox
SOX9Bgeehair follicle1.00infobox
SOX9Bgeeoptic nerve1.00infobox
SOX9Bgeeparotid gland1.00infobox
SOX9Bgeeretinal pigment epithelium1.00infobox
SOX9Bgeeinternal globus pallidus1.00infobox
SOX9Bgeelactiferous duct1.00infobox
SOX9Bgeebuccal mucosa cell1.00infobox
SOX9Bgeecartilage tissue1.00infobox
SOX9Bgeepylorus1.00infobox
SOX9Bgeedigit1.00infobox
SOX9Bgeecartilage organ1.00infobox
SOX9Bgeesphenoid bone1.00infobox
SOX9Bgeetoe1.00infobox
SOX9Bgeebasisphenoid1.00infobox
SOX9Bgeelacrimal gland1.00infobox
SOX9Bgeemain bronchus1.00infobox
SOX9Bgeesecond toe1.00infobox
SOX9Bgeeepithelium of seminiferous tubule of testis1.00infobox
SOX9Bgeecervical loop1.00infobox
SOX9BioGPSMore reference expression data1.00infobox
SOX9Chr.Chromosome 17 (human)1.00infobox
SOX9Chr.Chromosome 11 (mouse)1.00infobox
SOX9DatabasesNCBI: entry; OMA: entry1.00infobox
SOX9End72,126,416 bp1.00infobox
SOX9End112,678,586 bp1.00infobox

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