EHMT2

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Explore the main themes, entities and connections around EHMT2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

G9a-like protein Repressive Epigenetic regulation Nucleus accumbens Addiction

11 related topics

EHMT2 in cancer

Tumorigenicity Leukemia Solid tumors Colorectal cancer Lung cancer

5 related topics

Interactions

Interact KIAA0515

2 related topics

Overview

Histone methyltransferase Enzyme Gene Histone H3 Lysine

9 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.1.1.367: ↗
Aliases: EHMT2, BAT8, C6orf30, G9A, GAT8, KMT1C, NG36, euchromatic histone lysine methyltransferase 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O8J, 3DM1, 3K5K, 3RJW, 4NVQ, 5JJ0, 5JHN, 5JIN
Band: 6p21.33 · 17 B1|17 18.45 cM
Bgee: nucleus accumbens · ganglionic eminence · putamen · ventricular zone · right frontal lobe
BioGPS: More reference expression data

Topics to explore

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Overview

Histone methyltransferase
Enzyme
Gene
Histone H3
Lysine
H3K9me1 H3K9me1?action=edit&redlink=1
H3K9me2
H3K27me1 H3K27me1?action=edit&redlink=1
Gene silencing

Function

Interactions

Interact Protein-protein interaction
KIAA0515

EHMT2 in cancer

Advanced semantic analysis

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Map overview Semantic statistics

Nodes32

Edges31

Triples98

Avg. degree1.94

Density0.0625

Components1

How this topic connects Entity context

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EHMT2

Top relations

Gene ontology · 29

EHMT2 → C2H2 zinc finger domain binding, cellular response to starvation, chromatin organization, chromosome, DNA methylation, histone H3-K27 methylation, histone H3-K9 methylation, histone lysine methylation, histone methylation, histone methyltransferase activity (H3-K27 specific), histone methyltransferase activity (H3-K9 specific), histone-lysine N-methyltransferase activity, metal ion binding, methylation, methyltransferase activity, negative regulation of G0 to G1 transition, negative regulation of transcription by RNA polymerase II, nuclear speck, nucleoplasm, nucleus

Bgee · 19

EHMT2 → amygdala, anterior cingulate cortex, caudate nucleus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, ganglionic eminence, Gonadal ridge, nucleus accumbens, perirhinal cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, seminiferous tubule, spermatid, spermatocyte, superior frontal gyrus, temporal lobe, ventricular zone

RNA expression pattern · 19

Band · 2

EHMT2 → 17 B1|17 18.45 cM, 6p21.33

Chr. · 2

EHMT2 → Chromosome 17 (mouse), Chromosome 6 (human)

End · 2

EHMT2 → 31,897,687 bp, 35,133,028 bp

related to Interactions · 2

EHMT2 → KIAA0515, NKX3

2.1.1.367 · 1

EHMT2 → ↗

Aliases · 1

EHMT2 → EHMT2, BAT8, C6orf30, G9A, GAT8, KMT1C, NG36, euchromatic histone lysine methyltransferase 2

Available structures · 1

EHMT2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O8J, 3DM1, 3K5K, 3RJW, 4NVQ, 5JJ0, 5JHN, 5JIN

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene g9a bp human chr chromosome band histone expression lysine methyltransferase h3k9me2 nucleus h3k9me1 accumbens protein histone-lysine n-methyltransferase location function

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
EHMT2	2.1.1.367	↗	1.00	infobox
EHMT2	Aliases	EHMT2, BAT8, C6orf30, G9A, GAT8, KMT1C, NG36, euchromatic histone lysine methyltransferase 2	1.00	infobox
EHMT2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2O8J, 3DM1, 3K5K, 3RJW, 4NVQ, 5JJ0, 5JHN, 5JIN	1.00	infobox
EHMT2	Band	6p21.33	1.00	infobox
EHMT2	Band	17 B1\|17 18.45 cM	1.00	infobox
EHMT2	Bgee	nucleus accumbens	1.00	infobox
EHMT2	Bgee	ganglionic eminence	1.00	infobox
EHMT2	Bgee	putamen	1.00	infobox
EHMT2	Bgee	ventricular zone	1.00	infobox
EHMT2	Bgee	right frontal lobe	1.00	infobox
EHMT2	Bgee	right hemisphere of cerebellum	1.00	infobox
EHMT2	Bgee	caudate nucleus	1.00	infobox
EHMT2	Bgee	temporal lobe	1.00	infobox
EHMT2	Bgee	amygdala	1.00	infobox
EHMT2	Bgee	anterior cingulate cortex	1.00	infobox
EHMT2	Bgee	Gonadal ridge	1.00	infobox
EHMT2	Bgee	spermatid	1.00	infobox
EHMT2	Bgee	entorhinal cortex	1.00	infobox
EHMT2	Bgee	seminiferous tubule	1.00	infobox
EHMT2	Bgee	perirhinal cortex	1.00	infobox
EHMT2	Bgee	spermatocyte	1.00	infobox
EHMT2	Bgee	superior frontal gyrus	1.00	infobox
EHMT2	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
EHMT2	Bgee	primary visual cortex	1.00	infobox
EHMT2	BioGPS	More reference expression data	1.00	infobox
EHMT2	Chr.	Chromosome 6 (human)	1.00	infobox
EHMT2	Chr.	Chromosome 17 (mouse)	1.00	infobox
EHMT2	Databases	NCBI: entry; OMA: entry	1.00	infobox
EHMT2	End	31,897,687 bp	1.00	infobox
EHMT2	End	35,133,028 bp	1.00	infobox

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