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Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around MAD2L2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around MAD2L2 shows recurring relationship patterns in the source. For example, MAD2L2 → actin filament organization, anaphase-promoting complex, cell cycle, cell division, cellular response to DNA damage stimulus, chromosome, cytoplasm, cytoskeleton, cytosol, DNA damage response, signal transduction resulting in transcription, DNA repair, double-strand break repair, error-prone translesion synthesis, JUN kinase binding, mitotic spindle assembly checkpoint signaling, negative regulation of canonical Wnt signaling pathway, negative regulation of cell-cell adhesion mediated by cadherin, negative regulation of DNA-binding transcription factor activity, negative regulation of double-strand break repair via homologous recombination, negative regulation of epithelial to mesenchymal transition Another extracted example is MAD2L2 → body of pancreas, external carotid artery, ganglionic eminence, gastrocnemius muscle, genital tubercle, granulocyte, left testis, morula, muscle of thigh, neural tube, right lobe of liver, right testis, secondary oocyte, seminiferous tubule, spermatocyte, stromal cell of endometrium, tail of embryo, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp chr human chromosome band gene mitotic spindle assembly checkpoint location protein mouse mad2b function external search 691 650 end
TTTA extracted 105 structured relationships around MAD2L2. Examples in this analysis include MAD2L2 → Aliases → MAD2L2, MAD2B, POLZ2, REV7, MAD2 mitotic arrest deficient-like 2 (yeast), mitotic arrest deficient 2 like 2, FANCV and MAD2L2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ABD, 3ABE, 3VU7, 4EXT, 4GK0, 4GK5. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAD2L2 | Aliases | MAD2L2, MAD2B, POLZ2, REV7, MAD2 mitotic arrest deficient-like 2 (yeast), mitotic arrest deficient 2 like 2, FANCV | 1.00 | infobox |
| MAD2L2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ABD, 3ABE, 3VU7, 4EXT, 4GK0, 4GK5 | 1.00 | infobox |
| MAD2L2 | Band | 1p36.22 | 1.00 | infobox |
| MAD2L2 | Band | 4|4 E2 | 1.00 | infobox |
| MAD2L2 | Bgee | ganglionic eminence | 1.00 | infobox |
| MAD2L2 | Bgee | left testis | 1.00 | infobox |
| MAD2L2 | Bgee | right testis | 1.00 | infobox |
| MAD2L2 | Bgee | granulocyte | 1.00 | infobox |
| MAD2L2 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| MAD2L2 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| MAD2L2 | Bgee | ventricular zone | 1.00 | infobox |
| MAD2L2 | Bgee | muscle of thigh | 1.00 | infobox |
| MAD2L2 | Bgee | right lobe of liver | 1.00 | infobox |
| MAD2L2 | Bgee | body of pancreas | 1.00 | infobox |
| MAD2L2 | Bgee | genital tubercle | 1.00 | infobox |
| MAD2L2 | Bgee | seminiferous tubule | 1.00 | infobox |
| MAD2L2 | Bgee | tail of embryo | 1.00 | infobox |
| MAD2L2 | Bgee | spermatocyte | 1.00 | infobox |
| MAD2L2 | Bgee | zygote | 1.00 | infobox |
| MAD2L2 | Bgee | morula | 1.00 | infobox |
| MAD2L2 | Bgee | secondary oocyte | 1.00 | infobox |
| MAD2L2 | Bgee | external carotid artery | 1.00 | infobox |
| MAD2L2 | Bgee | neural tube | 1.00 | infobox |
| MAD2L2 | BioGPS | n/a | 1.00 | infobox |
| MAD2L2 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| MAD2L2 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| MAD2L2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAD2L2 | End | 11,691,650 bp | 1.00 | infobox |
| MAD2L2 | End | 148,145,699 bp | 1.00 | infobox |
| MAD2L2 | Ensembl | ENSG00000116670 | 1.00 | infobox |
The concept neighborhoods around MAD2L2 bring nearby vocabulary together. In this analysis, examples include Mitotic, Gene and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAD2L2, one of the stronger structural bridges in this analysis connects MAD2L2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAD2L2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAD2L2 · EN edition · Analysis: TopicsToTalkAbout