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Kozak consensus sequence

The Kozak consensus sequence (Kozak consensus or Kozak sequence) is a nucleic acid motif that functions as the protein translation initiation site in most eukaryotic mRNA transcripts. Regarded as the optimum sequence for initiating translation in eukaryotes, the sequence is an integral aspect of protein regulation and overall cellular health as well as…

Regions, Ribosome assembly & Sequence

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Ribosome assembly

Ribosomal complexEIF2EIF1EIF5EIF3
15 related topics

Sequence

Site-directed mutagenesisXenopusBasesStart codonMethionine
8 related topics

Mutations and disease

Thalassaemia intermediaCongenital heart diseaseGATA4SOX9Open reading frame
6 related topics

Differences from bacterial initiation

Shine-Dalgarno (SD) sequence16SArchaealLeaderlessHsp70
5 related topics

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Overview

Sequence

Ribosome assembly

Differences from bacterial initiation

Mutations and disease

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Kozak consensus sequence

Nodes50
Edges49
Triples14
Avg. degree1.96
Density0.04
Components1

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Kozak consensus sequence

Top relations

related to Differences from bacterial initiation · 14
Kozak consensus sequence → An, Archaeal, AUG, GUG, Haloarchaea, Hsp70, In, Kozak, SD, Shine-Dalgarno, The, The SD, The Shine Dalgarno, UUG

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Important terminology

sequence kozak translation mrna initiation codon ribosome protein consensus aug start site scanning position first pic complex end eukaryotes methionine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Kozak consensus sequencerelated to Differences from bacterial initiationThe0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationKozak0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationShine-Dalgarno0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationSD0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationThe SD0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationThe Shine Dalgarno0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationAUG0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationIn0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationAn0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationUUG0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationGUG0.60section
Kozak consensus sequencerelated to Differences from bacterial initiationArchaeal0.60section

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