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Juxtacrine signalling

In biology, juxtacrine signalling (or contact-dependent signalling) is a type of cell–cell or cell–extracellular matrix signalling in multicellular organisms that requires close contact. In this type of signalling, a ligand on one surface binds to a receptor on another adjacent surface. Hence, this stands in contrast to releasing a signaling molecule by…

Communicating junctions, Overview & Cell–extracellular matrix signaling

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Communicating junctions

Gap junctionsAnimalsPlasmodesmataPlantsConnexins
12 related topics

Overview

CellExtracellular matrixSignallingMulticellularDiffusion
30 related topics

Cell–extracellular matrix signaling

MucopolysaccharidesFibronectinVitronectinIntegrinCell cycle
6 related topics

Cell–cell signaling

Cell surface receptorCell adhesion moleculeNotch signaling pathway
3 related topics

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Overview

Cell–cell signaling

Communicating junctions

Cell–extracellular matrix signaling

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Juxtacrine signalling

Nodes56
Edges55
Triples5
Avg. degree1.96
Density0.035714
Components1

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Important terminology

signaling cell cells juxtracrine extracellular membrane adjacent matrix type role signalling receptor molecules contact also interact proteins intracellular paracrine autocrine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
bacteriainstance ofin unicellular organisms0.80text
juxtracrine signaling refers to interactions by membrane contact.Juxtracrine signaling has been observed for some growth factorsinstance ofin unicellular organisms0.80text
cytokineinstance ofin unicellular organisms0.80text
chemokine cellular signalsinstance ofin unicellular organisms0.80text
playing an important role in the immune responseinstance ofin unicellular organisms0.80text

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