HEY2

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Explore the main themes, entities and connections around HEY2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Expression

Notch signaling pathway Neurogenesis Somitogenesis

3 related topics

Clinical significance

SCN5A SCN10A Brugada syndrome

3 related topics

Interactions

Interact Sirtuin 1 Nuclear receptor co-repressor 1

3 related topics

Knockout studies

Cardiovascular system Gene knockout

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: HEY2, CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32, hes related family bHLH transcription factor with YRPW motif 2
Band: 6q22.31 · 10|10 A4
Bgee: popliteal artery · tibial arteries · right ventricle · myocardium of left ventricle · right coronary artery
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 10 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Protein
Gene
Transcription factors Transcription factor
BHLH Basic helix-loop-helix
Histone deacetylase
Transcription Transcription (genetics)

Expression

Knockout studies

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes23

Edges22

Triples175

Avg. degree1.91

Density0.086957

Components1

How this topic connects Entity context

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HEY2

Top relations

Gene ontology · 91

HEY2 → anterior/posterior axis specification, anterior/posterior pattern specification, aortic valve morphogenesis, arterial endothelial cell differentiation, artery development, ascending aorta morphogenesis, atrial septum morphogenesis, atrioventricular valve development, blood vessel development, cardiac epithelial to mesenchymal transition, cardiac left ventricle morphogenesis, cardiac muscle hypertrophy, cardiac muscle hypertrophy in response to stress, cardiac right ventricle morphogenesis, cardiac septum morphogenesis, cardiac vascular smooth muscle cell development, cardiac ventricle morphogenesis, cell differentiation, cell fate commitment, circulatory system development

Bgee · 20

HEY2 → aortic valve, ascending aorta, corpus epididymis, cumulus cell, Descending thoracic aorta, inner enamel epithelium, left ventricle, lumbar spinal ganglion, myocardium of left ventricle, oocyte, popliteal artery, primordial ventricle, right coronary artery, right uterine tube, right ventricle, secondary oocyte, semi-lunar valve, tibial arteries, trigeminal ganglion, tunica media of zone of aorta

RNA expression pattern · 20

related to Knockout studies · 7

HEY2 → Although, Hey1, It, The, The Hey2, Using, When

related to External links · 6

HEY2 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library

related to Expression · 5

HEY2 → Alternatively, In, Notch, The, Two

related to Clinical significance · 4

HEY2 → Brugada, Common, SCN10A, SCN5A

Band · 2

HEY2 → 10|10 A4, 6q22.31

Chr. · 2

HEY2 → Chromosome 10 (mouse), Chromosome 6 (human)

End · 2

HEY2 → 125,761,269 bp, 30,718,797 bp

Important terminology Word statistics

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Important terminology

gene transcription bp human chr band protein factor chromosome development related chf1 expression number cells mouse heart location genes cardiovascular

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
HEY2	Aliases	HEY2, CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32, hes related family bHLH transcription factor with YRPW motif 2	1.00	infobox
HEY2	Band	6q22.31	1.00	infobox
HEY2	Band	10\|10 A4	1.00	infobox
HEY2	Bgee	popliteal artery	1.00	infobox
HEY2	Bgee	tibial arteries	1.00	infobox
HEY2	Bgee	right ventricle	1.00	infobox
HEY2	Bgee	myocardium of left ventricle	1.00	infobox
HEY2	Bgee	right coronary artery	1.00	infobox
HEY2	Bgee	oocyte	1.00	infobox
HEY2	Bgee	Descending thoracic aorta	1.00	infobox
HEY2	Bgee	secondary oocyte	1.00	infobox
HEY2	Bgee	right uterine tube	1.00	infobox
HEY2	Bgee	corpus epididymis	1.00	infobox
HEY2	Bgee	trigeminal ganglion	1.00	infobox
HEY2	Bgee	ascending aorta	1.00	infobox
HEY2	Bgee	inner enamel epithelium	1.00	infobox
HEY2	Bgee	left ventricle	1.00	infobox
HEY2	Bgee	tunica media of zone of aorta	1.00	infobox
HEY2	Bgee	cumulus cell	1.00	infobox
HEY2	Bgee	primordial ventricle	1.00	infobox
HEY2	Bgee	semi-lunar valve	1.00	infobox
HEY2	Bgee	aortic valve	1.00	infobox
HEY2	Bgee	lumbar spinal ganglion	1.00	infobox
HEY2	BioGPS	More reference expression data	1.00	infobox
HEY2	Chr.	Chromosome 6 (human)	1.00	infobox
HEY2	Chr.	Chromosome 10 (mouse)	1.00	infobox
HEY2	Databases	NCBI: entry; OMA: entry	1.00	infobox
HEY2	End	125,761,269 bp	1.00	infobox
HEY2	End	30,718,797 bp	1.00	infobox
HEY2	Ensembl	ENSG00000135547	1.00	infobox

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