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Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) also known as cardiovascular helix-loop-helix factor 1 (CHF1) is a protein that in humans is encoded by the HEY2 gene.
The analysis highlights Research, Expression and Clinical significance as prominent areas in the source structure around HEY2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around HEY2 shows recurring relationship patterns in the source. For example, HEY2 → anterior/posterior axis specification, anterior/posterior pattern specification, aortic valve morphogenesis, arterial endothelial cell differentiation, artery development, ascending aorta morphogenesis, atrial septum morphogenesis, atrioventricular valve development, blood vessel development, cardiac epithelial to mesenchymal transition, cardiac left ventricle morphogenesis, cardiac muscle hypertrophy, cardiac muscle hypertrophy in response to stress, cardiac right ventricle morphogenesis, cardiac septum morphogenesis, cardiac vascular smooth muscle cell development, cardiac ventricle morphogenesis, cell differentiation, cell fate commitment, circulatory system development Another extracted example is HEY2 → aortic valve, ascending aorta, corpus epididymis, cumulus cell, Descending thoracic aorta, inner enamel epithelium, left ventricle, lumbar spinal ganglion, myocardium of left ventricle, oocyte, popliteal artery, primordial ventricle, right coronary artery, right uterine tube, right ventricle, secondary oocyte, semi-lunar valve, tibial arteries, trigeminal ganglion, tunica media of zone of aorta. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene transcription bp human chr band protein factor chromosome development related chf1 expression number cells mouse heart location genes cardiovascular
TTTA extracted 164 structured relationships around HEY2. Examples in this analysis include HEY2 → Aliases → HEY2, CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32, hes related family bHLH transcription factor with YRPW motif 2 and HEY2 → Band → 6q22.31. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HEY2 | Aliases | HEY2, CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32, hes related family bHLH transcription factor with YRPW motif 2 | 1.00 | infobox |
| HEY2 | Band | 6q22.31 | 1.00 | infobox |
| HEY2 | Band | 10|10 A4 | 1.00 | infobox |
| HEY2 | Bgee | popliteal artery | 1.00 | infobox |
| HEY2 | Bgee | tibial arteries | 1.00 | infobox |
| HEY2 | Bgee | right ventricle | 1.00 | infobox |
| HEY2 | Bgee | myocardium of left ventricle | 1.00 | infobox |
| HEY2 | Bgee | right coronary artery | 1.00 | infobox |
| HEY2 | Bgee | oocyte | 1.00 | infobox |
| HEY2 | Bgee | Descending thoracic aorta | 1.00 | infobox |
| HEY2 | Bgee | secondary oocyte | 1.00 | infobox |
| HEY2 | Bgee | right uterine tube | 1.00 | infobox |
| HEY2 | Bgee | corpus epididymis | 1.00 | infobox |
| HEY2 | Bgee | trigeminal ganglion | 1.00 | infobox |
| HEY2 | Bgee | ascending aorta | 1.00 | infobox |
| HEY2 | Bgee | inner enamel epithelium | 1.00 | infobox |
| HEY2 | Bgee | left ventricle | 1.00 | infobox |
| HEY2 | Bgee | tunica media of zone of aorta | 1.00 | infobox |
| HEY2 | Bgee | cumulus cell | 1.00 | infobox |
| HEY2 | Bgee | primordial ventricle | 1.00 | infobox |
| HEY2 | Bgee | semi-lunar valve | 1.00 | infobox |
| HEY2 | Bgee | aortic valve | 1.00 | infobox |
| HEY2 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| HEY2 | BioGPS | More reference expression data | 1.00 | infobox |
| HEY2 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| HEY2 | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| HEY2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| HEY2 | End | 125,761,269 bp | 1.00 | infobox |
| HEY2 | End | 30,718,797 bp | 1.00 | infobox |
| HEY2 | Ensembl | ENSG00000135547 | 1.00 | infobox |
The concept neighborhoods around HEY2 bring nearby vocabulary together. In this analysis, examples include Expression, Related and Heart. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For HEY2, one of the stronger structural bridges in this analysis connects HEY2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around HEY2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Expression & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — HEY2 · EN edition · Analysis: TopicsToTalkAbout
