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HDAC7

Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene.

Function, Interactions & Clinical signifance

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Function

10 related topics

Interactions

6 related topics

Clinical signifance

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Overview

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Key facts & relationships

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3.5.1.98
Aliases
HDAC7, HD7A, HDAC7A, HD7, histone deacetylase 7
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3C0Y, 3C0Z, 3C10, 3ZNR, 3ZNS
Band
12q13.11 · 15|15 F1
Bgee
sural nerve · gastric mucosa · left uterine tube · body of uterus · apex of heart
BioGPS
More reference expression data

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Overview

Function

Clinical signifance

Interactions

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Map overview Semantic statistics

HDAC7

Nodes28
Edges27
Triples132
Avg. degree1.93
Density0.071429
Components1

How this topic connects Entity context

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HDAC7

Top relations

Gene ontology · 30
HDAC7 → 14-3-3 protein binding, cell-cell junction assembly, chromatin binding, chromatin organization, cytoplasm, cytosol, histone deacetylase activity, histone deacetylase complex, histone deacetylation, histone H3 deacetylation, hydrolase activity, metal ion binding, NAD-dependent histone deacetylase activity (H3-K14 specific), negative regulation of interleukin-2 production, negative regulation of NIK/NF-kappaB signaling, negative regulation of osteoblast differentiation, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus
Bgee · 20
HDAC7 → aortic valve, apex of heart, ascending aorta, body of uterus, canal of the cervix, corneal stroma, entorhinal cortex, gastric mucosa, genital tubercle, lactiferous gland, left adrenal cortex, left uterine tube, otic vesicle, perirhinal cortex, right ovary, right uterine tube, sural nerve, tail of embryo, thymus, upper lobe of left lung
RNA expression pattern · 20
HDAC7 → aortic valve, apex of heart, ascending aorta, body of uterus, canal of the cervix, corneal stroma, entorhinal cortex, gastric mucosa, genital tubercle, lactiferous gland, left adrenal cortex, left uterine tube, otic vesicle, perirhinal cortex, right ovary, right uterine tube, sural nerve, tail of embryo, thymus, upper lobe of left lung
related to Function · 14
HDAC7 → CaMK, DNA, HClass IIa HDACs, HDAC, HDAC3, Histone, Histones, IIa HDAC, IIa HDAC-specific, It, PKD, SMRT, The, This
related to Clinical signifance · 9
HDAC7 → HDAC-dependent, HIF-1alpha-dependent, LPS, Myc, Not, Outside, Subsequently, This, Through
related to External links · 7
HDAC7 → HDAC7A, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
related to Interactions · 6
HDAC7 → BCL6, Endothelin, HDAC3, HDAC7A, HTATIP, IKZF1
Band · 2
HDAC7 → 12q13.11, 15|15 F1
Chr. · 2
HDAC7 → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
HDAC7 → 47,833,132 bp, 97,742,383 bp

Important terminology Word statistics

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Important terminology

gene cell human deacetylase bp study histone β-catenin chr band activity chromosome shown proliferation 12 protein class iia cycle demonstrated

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HDAC73.5.1.981.00infobox
HDAC7AliasesHDAC7, HD7A, HDAC7A, HD7, histone deacetylase 71.00infobox
HDAC7Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3C0Y, 3C0Z, 3C10, 3ZNR, 3ZNS1.00infobox
HDAC7Band12q13.111.00infobox
HDAC7Band15|15 F11.00infobox
HDAC7Bgeesural nerve1.00infobox
HDAC7Bgeegastric mucosa1.00infobox
HDAC7Bgeeleft uterine tube1.00infobox
HDAC7Bgeebody of uterus1.00infobox
HDAC7Bgeeapex of heart1.00infobox
HDAC7Bgeeupper lobe of left lung1.00infobox
HDAC7Bgeeleft adrenal cortex1.00infobox
HDAC7Bgeecanal of the cervix1.00infobox
HDAC7Bgeeright ovary1.00infobox
HDAC7Bgeeright uterine tube1.00infobox
HDAC7Bgeethymus1.00infobox
HDAC7Bgeegenital tubercle1.00infobox
HDAC7Bgeecorneal stroma1.00infobox
HDAC7Bgeeotic vesicle1.00infobox
HDAC7Bgeeentorhinal cortex1.00infobox
HDAC7Bgeeperirhinal cortex1.00infobox
HDAC7Bgeelactiferous gland1.00infobox
HDAC7Bgeeascending aorta1.00infobox
HDAC7Bgeeaortic valve1.00infobox
HDAC7Bgeetail of embryo1.00infobox
HDAC7BioGPSMore reference expression data1.00infobox
HDAC7Chr.Chromosome 12 (human)1.00infobox
HDAC7Chr.Chromosome 15 (mouse)1.00infobox
HDAC7DatabasesNCBI: entry; OMA: entry1.00infobox
HDAC7End47,833,132 bp1.00infobox

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