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TAF1: Measurement, Function & Interactions

Transcription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit (TAFII-250) or TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene.

Language: English [EN]
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TAF1 topic overview

The analysis highlights Measurement, Function and Interactions as prominent areas in the source structure around TAF1.

Related topics
20
Source areas
4
Connected nodes
24
Extracted relationships
170
Concept neighborhoods
10
Bridge connections
24

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 10 topics
Interactions · 7 topics
Overview · 2 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.1.48
2.7.11.1
Aliases
TAF1, BA2R, CCG1, CCGS, DYT3, DYT3/KAT4, N-NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP, MRXS33, TATA-box binding protein associated factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EQF, 3AAD, 3UV4, 3UV5, 4RGW, 4YYM, 4YYN, 5I29, 5I1Q, 5FUR
Band
Xq13.1 · X D|X 44.29 cM
Bgee
sural nerve · Achilles tendon · epithelium of colon · urethra · tonsil

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How TAF1 connects Entity context

The extracted context around TAF1 shows recurring relationship patterns in the source. For example, TAF1 → acetyl-CoA binding, acyltransferase activity, ATP binding, cell cycle, cellular response to ATP, cellular response to DNA damage stimulus, cellular response to UV, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-templated transcription, initiation, H3K27me3 modified histone binding, histone acetylation, histone acetyltransferase activity, kinase activity, lysine-acetylated histone binding, midbrain development, MLL1 complex, negative regulation of DNA-binding transcription factor activity, negative regulation of gene expression, negative regulation of protein autoubiquitination Another extracted example is TAF1 → Achilles tendon, arcuate nucleus, body of uterus, corpus callosum, dentate gyrus of hippocampal formation granule cell, epithelium of colon, Gonadal ridge, hand, lactiferous duct, left ovary, maxillary prominence, neural layer of retina, pericardium, Rostral migratory stream, sural nerve, tail of embryo, tonsil, urethra, ventral tegmental area, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

TAF1

Top relations

Gene ontology · 66
TAF1 → acetyl-CoA binding, acyltransferase activity, ATP binding, cell cycle, cellular response to ATP, cellular response to DNA damage stimulus, cellular response to UV, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-templated transcription, initiation, H3K27me3 modified histone binding, histone acetylation, histone acetyltransferase activity, kinase activity, lysine-acetylated histone binding, midbrain development, MLL1 complex, negative regulation of DNA-binding transcription factor activity, negative regulation of gene expression, negative regulation of protein autoubiquitination
Bgee · 20
TAF1 → Achilles tendon, arcuate nucleus, body of uterus, corpus callosum, dentate gyrus of hippocampal formation granule cell, epithelium of colon, Gonadal ridge, hand, lactiferous duct, left ovary, maxillary prominence, neural layer of retina, pericardium, Rostral migratory stream, sural nerve, tail of embryo, tonsil, urethra, ventral tegmental area, ventricular zone
RNA expression pattern · 20
TAF1 → Achilles tendon, arcuate nucleus, body of uterus, corpus callosum, dentate gyrus of hippocampal formation granule cell, epithelium of colon, Gonadal ridge, hand, lactiferous duct, left ovary, maxillary prominence, neural layer of retina, pericardium, Rostral migratory stream, sural nerve, tail of embryo, tonsil, urethra, ventral tegmental area, ventricular zone
related to Function · 18
TAF1 → C-terminals, DNA, GTFs, H4, Histones, II, Initiation, It, RNA, TAFs, TATA-binding, TBP, TBP-associated, TBP-TATA, TFIID, The, This, Two
related to External links · 11
TAF1 → FactorBookTAF1GeneReviews/NCBI/NIH/UW, Medicine, P21675, PDB, PDBe-KB, TFIID, This, Transcription, UniProt, United States National Library, X-Linked Dystonia-Parkinsonismhttp
related to Interactions · 6
TAF1 → CCND1, CSNK2A1, GTF2F1, RB1, TAF7, TBP
related to Clinical significance · 3
TAF1 → ID, This, Two
Band · 2
TAF1 → X D|X 44.29 cM, Xq13.1
Chr. · 2
TAF1 → X chromosome (human), X chromosome (mouse)
End · 2
TAF1 → 100,645,395 bp, 71,532,374 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

transcription protein tfiid bp gene initiation chr human band factor subunit chromosome also promoter ii complex location function two enzyme

TAF1 relationships Subject–Predicate–Object triples

TTTA extracted 170 structured relationships around TAF1. Examples in this analysis include TAF1 → 2.3.1.48 → ↗ and TAF1 → Aliases → TAF1, BA2R, CCG1, CCGS, DYT3, DYT3/KAT4, N-NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP, MRXS33, TATA-box binding protein associated factor 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TAF12.3.1.481.00infobox
TAF12.7.11.11.00infobox
TAF1AliasesTAF1, BA2R, CCG1, CCGS, DYT3, DYT3/KAT4, N-NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP, MRXS33, TATA-box binding protein associated factor 11.00infobox
TAF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EQF, 3AAD, 3UV4, 3UV5, 4RGW, 4YYM, 4YYN, 5I29, 5I1Q, 5FUR1.00infobox
TAF1BandXq13.11.00infobox
TAF1BandX D|X 44.29 cM1.00infobox
TAF1Bgeesural nerve1.00infobox
TAF1BgeeAchilles tendon1.00infobox
TAF1Bgeeepithelium of colon1.00infobox
TAF1Bgeeurethra1.00infobox
TAF1Bgeetonsil1.00infobox
TAF1Bgeeleft ovary1.00infobox
TAF1Bgeelactiferous duct1.00infobox
TAF1Bgeepericardium1.00infobox
TAF1Bgeecorpus callosum1.00infobox
TAF1Bgeebody of uterus1.00infobox
TAF1Bgeehand1.00infobox
TAF1Bgeeneural layer of retina1.00infobox
TAF1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
TAF1BgeeGonadal ridge1.00infobox
TAF1BgeeRostral migratory stream1.00infobox
TAF1Bgeeventricular zone1.00infobox
TAF1Bgeemaxillary prominence1.00infobox
TAF1Bgeeventral tegmental area1.00infobox
TAF1Bgeetail of embryo1.00infobox
TAF1Bgeearcuate nucleus1.00infobox
TAF1BioGPSMore reference expression data1.00infobox
TAF1Chr.X chromosome (human)1.00infobox
TAF1Chr.X chromosome (mouse)1.00infobox
TAF1DatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around TAF1 bring nearby vocabulary together. In this analysis, examples include Gene, Binding and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • TAF1
    • Gene
    • Binding
    • Search
    • Tafii-250
    • Activity
    • Enzyme
    • Function
    • Ii
    • Location
    • Chromosome
    • Complex
    • Human
  • taf1
    • Gene
    • Binding
    • Search
    • Tafii-250
    • Activity
    • Enzyme
    • Function
    • Ii
    • Location
    • Chromosome
    • Complex
    • Human
  • protein
    • Tfiid
    • Activity
    • Enzyme
    • Taf1
    • Gene
    • Binding
    • Polymerase
    • Search
    • Tafii-250
    • Tbp-associated
    • Assembly
    • Core
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Binding
    • Mouse
    • P250
    • Search
    • Tafii-250
    • Tfiid
    • Protein
  • tfiid
    • Protein
    • Transcription
    • Subunit
    • Gene
    • Known
    • P21675
    • Polymerase
    • Tbp-associated
    • Uniprot
    • Assembly
    • Core
    • Ii
  • protein kinase
    • Tfiid
    • Activity
    • Enzyme
    • Taf1
    • Gene
    • Binding
    • Polymerase
    • Search
    • Tafii-250
    • Tbp-associated
    • Assembly
    • Core
  • function
    • Binding
    • Search
    • Activity
    • Assembly
    • Enzyme
    • Ii
    • Location
    • Chromosome
    • Complex
    • Human
    • Promoter
    • Bp
  • rna polymerase ii
    • P21675
    • Pdb
    • Search
    • Uniprot
    • Location
    • Promoter
    • Human
    • Initiation
    • Tfiid
    • Protein
    • Binds
    • Mouse

Connections between topic areas Semantic bridges

For TAF1, one of the stronger structural bridges in this analysis connects TAF1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TAF1Function · splits 14 ⟂ 11
TAF1Interactions · splits 17 ⟂ 8
TAF1Overview · splits 22 ⟂ 3

Map overview Semantic statistics

TAF1

Nodes25
Edges24
Triples170
Avg. degree1.92
Density0.08
Components1

Source & methodology

TTTA analyzes the structure around TAF1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — TAF1 · EN edition · Analysis: TopicsToTalkAbout

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