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TAF1

Transcription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit (TAFII-250) or TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene.

Measurement, Function & Interactions

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Function

10 related topics

Interactions

7 related topics

Clinical significance

1 related topics

Overview

2 related topics

Key facts & relationships

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2.3.1.48
2.7.11.1
Aliases
TAF1, BA2R, CCG1, CCGS, DYT3, DYT3/KAT4, N-NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP, MRXS33, TATA-box binding protein associated factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EQF, 3AAD, 3UV4, 3UV5, 4RGW, 4YYM, 4YYN, 5I29, 5I1Q, 5FUR
Band
Xq13.1 · X D|X 44.29 cM
Bgee
sural nerve · Achilles tendon · epithelium of colon · urethra · tonsil

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Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

TAF1

Nodes25
Edges24
Triples170
Avg. degree1.92
Density0.08
Components1

How this topic connects Entity context

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TAF1

Top relations

Gene ontology · 66
TAF1 → acetyl-CoA binding, acyltransferase activity, ATP binding, cell cycle, cellular response to ATP, cellular response to DNA damage stimulus, cellular response to UV, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-templated transcription, initiation, H3K27me3 modified histone binding, histone acetylation, histone acetyltransferase activity, kinase activity, lysine-acetylated histone binding, midbrain development, MLL1 complex, negative regulation of DNA-binding transcription factor activity, negative regulation of gene expression, negative regulation of protein autoubiquitination
Bgee · 20
TAF1 → Achilles tendon, arcuate nucleus, body of uterus, corpus callosum, dentate gyrus of hippocampal formation granule cell, epithelium of colon, Gonadal ridge, hand, lactiferous duct, left ovary, maxillary prominence, neural layer of retina, pericardium, Rostral migratory stream, sural nerve, tail of embryo, tonsil, urethra, ventral tegmental area, ventricular zone
RNA expression pattern · 20
TAF1 → Achilles tendon, arcuate nucleus, body of uterus, corpus callosum, dentate gyrus of hippocampal formation granule cell, epithelium of colon, Gonadal ridge, hand, lactiferous duct, left ovary, maxillary prominence, neural layer of retina, pericardium, Rostral migratory stream, sural nerve, tail of embryo, tonsil, urethra, ventral tegmental area, ventricular zone
related to Function · 18
TAF1 → C-terminals, DNA, GTFs, H4, Histones, II, Initiation, It, RNA, TAFs, TATA-binding, TBP, TBP-associated, TBP-TATA, TFIID, The, This, Two
related to External links · 11
TAF1 → FactorBookTAF1GeneReviews/NCBI/NIH/UW, Medicine, P21675, PDB, PDBe-KB, TFIID, This, Transcription, UniProt, United States National Library, X-Linked Dystonia-Parkinsonismhttp
related to Interactions · 6
TAF1 → CCND1, CSNK2A1, GTF2F1, RB1, TAF7, TBP
related to Clinical significance · 3
TAF1 → ID, This, Two
Band · 2
TAF1 → X D|X 44.29 cM, Xq13.1
Chr. · 2
TAF1 → X chromosome (human), X chromosome (mouse)
End · 2
TAF1 → 100,645,395 bp, 71,532,374 bp

Important terminology Word statistics

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Important terminology

transcription protein tfiid bp gene initiation chr human band factor subunit chromosome also promoter ii complex location function two enzyme

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TAF12.3.1.481.00infobox
TAF12.7.11.11.00infobox
TAF1AliasesTAF1, BA2R, CCG1, CCGS, DYT3, DYT3/KAT4, N-NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP, MRXS33, TATA-box binding protein associated factor 11.00infobox
TAF1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EQF, 3AAD, 3UV4, 3UV5, 4RGW, 4YYM, 4YYN, 5I29, 5I1Q, 5FUR1.00infobox
TAF1BandXq13.11.00infobox
TAF1BandX D|X 44.29 cM1.00infobox
TAF1Bgeesural nerve1.00infobox
TAF1BgeeAchilles tendon1.00infobox
TAF1Bgeeepithelium of colon1.00infobox
TAF1Bgeeurethra1.00infobox
TAF1Bgeetonsil1.00infobox
TAF1Bgeeleft ovary1.00infobox
TAF1Bgeelactiferous duct1.00infobox
TAF1Bgeepericardium1.00infobox
TAF1Bgeecorpus callosum1.00infobox
TAF1Bgeebody of uterus1.00infobox
TAF1Bgeehand1.00infobox
TAF1Bgeeneural layer of retina1.00infobox
TAF1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
TAF1BgeeGonadal ridge1.00infobox
TAF1BgeeRostral migratory stream1.00infobox
TAF1Bgeeventricular zone1.00infobox
TAF1Bgeemaxillary prominence1.00infobox
TAF1Bgeeventral tegmental area1.00infobox
TAF1Bgeetail of embryo1.00infobox
TAF1Bgeearcuate nucleus1.00infobox
TAF1BioGPSMore reference expression data1.00infobox
TAF1Chr.X chromosome (human)1.00infobox
TAF1Chr.X chromosome (mouse)1.00infobox
TAF1DatabasesNCBI: entry; OMA: entry1.00infobox

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    Min side: 3
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