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GNMT: Function, Tissue distribution & Discovery

Glycine N-methyltransferase is an enzyme that in humans is encoded by the GNMT gene.

Language: English [EN]
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GNMT topic overview

The analysis highlights Function, Tissue distribution and Discovery as prominent areas in the source structure around GNMT.

Related topics
44
Source areas
7
Connected nodes
51
Extracted relationships
130
Concept neighborhoods
12
Bridge connections
51

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 15 topics
Tissue distribution · 10 topics
Discovery · 5 topics
Clinical significance · 4 topics
Inducer · 4 topics
Structure · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.1.1.20
↗
Aliases
GNMT, HEL-S-182mP, glycine N-methyltransferase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1R74, 2AZT
Band
6p21.1 · 17 22.9 cM|17 C
Bgee
body of pancreas · right lobe of liver · body of stomach · prostate · olfactory zone of nasal mucosa
BioGPS
More reference expression data

Suggested research paths

A focused starting point derived from the topic graph, ranked independently of the source article order.

Start with these areas

Less obvious directions

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Tissue distribution

Structure

Function

Clinical significance

Inducer

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GNMT connects Entity context

The extracted context around GNMT shows recurring relationship patterns in the source. For example, GNMT → anterior pituitary, apex of heart, body of pancreas, body of stomach, gallbladder, gastric mucosa, granulocyte, human kidney, left lobe of liver, lip, olfactory zone of nasal mucosa, parotid gland, pituitary gland, prostate, proximal tubule, pyloric antrum, right kidney, right lobe of liver, submandibular gland, vestibular membrane of cochlear duct Another extracted example is GNMT → cellular nitrogen compound metabolic process, cytoplasm, cytosol, folic acid binding, glycine binding, glycine N-methyltransferase activity, glycogen metabolic process, identical protein binding, methionine metabolic process, methylation, methyltransferase activity, one-carbon metabolic process, protein binding, protein homotetramerization, regulation of gluconeogenesis, S-adenosyl-L-methionine binding, S-adenosylhomocysteine metabolic process, S-adenosylmethionine metabolic process, sarcosine metabolic process, transferase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

GNMT

Top relations

Bgee · 20
GNMT → anterior pituitary, apex of heart, body of pancreas, body of stomach, gallbladder, gastric mucosa, granulocyte, human kidney, left lobe of liver, lip, olfactory zone of nasal mucosa, parotid gland, pituitary gland, prostate, proximal tubule, pyloric antrum, right kidney, right lobe of liver, submandibular gland, vestibular membrane of cochlear duct
Gene ontology · 20
GNMT → cellular nitrogen compound metabolic process, cytoplasm, cytosol, folic acid binding, glycine binding, glycine N-methyltransferase activity, glycogen metabolic process, identical protein binding, methionine metabolic process, methylation, methyltransferase activity, one-carbon metabolic process, protein binding, protein homotetramerization, regulation of gluconeogenesis, S-adenosyl-L-methionine binding, S-adenosylhomocysteine metabolic process, S-adenosylmethionine metabolic process, sarcosine metabolic process, transferase activity
RNA expression pattern · 20
GNMT → anterior pituitary, apex of heart, body of pancreas, body of stomach, gallbladder, gastric mucosa, granulocyte, human kidney, left lobe of liver, lip, olfactory zone of nasal mucosa, parotid gland, pituitary gland, prostate, proximal tubule, pyloric antrum, right kidney, right lobe of liver, submandibular gland, vestibular membrane of cochlear duct
related to Function · 17
GNMT → AdoHcy, AdoMet, An, CH3-H4PteGIu5, Glycine N-methyltransferase, In, N-methylglycine, PAH, S-adenosylhomocysteine, S-adenosylmethionine, SAH, SAM, SAM-dependent, Since SAM, The, Therefore, Thus
related to Discovery · 10
GNMT → Blumenstein, Chen, Cook, GMNT, However, In, Kerr, The, Wagner, Williams
related to Inducer · 6
GNMT → Asian, Huh7, O-galloyl-β-d-glucopyranoside, Paeonia, PGG, The
related to Structure · 6
GNMT → All GNMTs, Comparison, Escherichia, GNMTs, Mr, The
related to Tissue distribution · 3
GNMT → In, The, The GNMT
Band · 2
GNMT → 17 22.9 cM|17 C, 6p21.1
Chr. · 2
GNMT → Chromosome 17 (mouse), Chromosome 6 (human)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human protein liver enzyme bp gene chr band sam glycine n-methyltransferase chromosome pancreas activity mouse location methylation s-adenosylmethionine s-adenosylhomocysteine gnmts

GNMT relationships Subject–Predicate–Object triples

TTTA extracted 130 structured relationships around GNMT. Examples in this analysis include GNMT → 2.1.1.20 → ↗ and GNMT → Aliases → GNMT, HEL-S-182mP, glycine N-methyltransferase. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GNMT2.1.1.20↗1.00infobox
GNMTAliasesGNMT, HEL-S-182mP, glycine N-methyltransferase1.00infobox
GNMTAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1R74, 2AZT1.00infobox
GNMTBand6p21.11.00infobox
GNMTBand17 22.9 cM|17 C1.00infobox
GNMTBgeebody of pancreas1.00infobox
GNMTBgeeright lobe of liver1.00infobox
GNMTBgeebody of stomach1.00infobox
GNMTBgeeprostate1.00infobox
GNMTBgeeolfactory zone of nasal mucosa1.00infobox
GNMTBgeeapex of heart1.00infobox
GNMTBgeegranulocyte1.00infobox
GNMTBgeegastric mucosa1.00infobox
GNMTBgeepituitary gland1.00infobox
GNMTBgeeanterior pituitary1.00infobox
GNMTBgeeleft lobe of liver1.00infobox
GNMTBgeegallbladder1.00infobox
GNMTBgeeparotid gland1.00infobox
GNMTBgeeright kidney1.00infobox
GNMTBgeevestibular membrane of cochlear duct1.00infobox
GNMTBgeepyloric antrum1.00infobox
GNMTBgeeproximal tubule1.00infobox
GNMTBgeehuman kidney1.00infobox
GNMTBgeelip1.00infobox
GNMTBgeesubmandibular gland1.00infobox
GNMTBioGPSMore reference expression data1.00infobox
GNMTChr.Chromosome 6 (human)1.00infobox
GNMTChr.Chromosome 17 (mouse)1.00infobox
GNMTDatabasesNCBI: entry; OMA: entry1.00infobox
GNMTEnd42,963,880 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GNMT bring nearby vocabulary together. In this analysis, examples include Liver, Protein and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GNMT
    • Liver
    • Protein
    • Activity
    • Pancreas
    • Sah
    • Sam
    • Cells
    • Expressed
    • Kidney
    • S-adenosylhomocysteine
    • Therefore
    • N-methyltransferase
  • gnmt
    • Liver
    • Protein
    • Activity
    • Pancreas
    • Sah
    • Sam
    • Cells
    • Expressed
    • Kidney
    • S-adenosylhomocysteine
    • Therefore
    • N-methyltransferase
  • enzyme
    • Glycine
    • N-methyltransferase
    • Liver
    • Gene
    • Gnmt
    • Function
    • Search
    • Cells
    • Location
    • S-adenosylhomocysteine
    • S-adenosylmethionine
    • Activity
  • gene
    • Location
    • Chromosome
    • Glycine
    • N-methyltransferase
    • Human
    • Bp
    • Chr
    • Cm
    • End
    • Function
    • Search
    • Mouse
  • glycine n-methyltransferase
    • N-methyltransferase
    • Function
    • Gene
    • Search
    • Location
    • S-adenosylmethionine
    • Activity
    • Chromosome
    • Enzyme
    • Bp
    • Chr
    • Cm
  • function
    • Search
    • Location
    • Activity
    • Chromosome
    • Glycine
    • N-methyltransferase
    • Bp
    • Chr
    • Gene
    • Cm
    • End
    • Cellular
  • methylation
    • Search
    • Methyl
    • Molecular
    • Mouse
    • S-adenosylhomocysteine
    • S-adenosylmethionine
    • Therefore
    • N-methyltransferase
    • Pancreas
    • Sam
    • Protein
  • protein
    • Search
    • Cells
    • S-adenosylhomocysteine
    • S-adenosylmethionine
    • Therefore
    • Gnmts

Connections between topic areas Semantic bridges

For GNMT, one of the stronger structural bridges in this analysis connects GNMT with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GNMT — Function · splits 36 ⟂ 16
GNMT — Tissue distribution · splits 41 ⟂ 11
GNMT — Discovery · splits 46 ⟂ 6
GNMT — Structure · splits 47 ⟂ 5
GNMT — Clinical significance · splits 47 ⟂ 5
GNMT — Inducer · splits 47 ⟂ 5
GNMT — Overview · splits 49 ⟂ 3

Map overview Semantic statistics

GNMT

Nodes52
Edges51
Triples130
Avg. degree1.96
Density0.038462
Components1

Source & methodology

TTTA analyzes the structure around GNMT to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Tissue distribution & Discovery, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GNMT · EN edition · Analysis: TopicsToTalkAbout

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