Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

FMR1

FMR1 (Fragile X Messenger Ribonucleoprotein 1) is a human gene that codes for a protein called fragile X messenger ribonucleoprotein, or FMRP. This protein, most commonly found in the brain, is essential for normal cognitive development and female reproductive function. Mutations of this gene can lead to fragile X syndrome, intellectual disability, FXPOI…

Products, Function & Gene expression

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around FMR1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
FMR1, FMRP, FRAXA, POF, POF1, fragile X mental retardation 1, FMRP translational regulator 1, fragile X messenger ribonucleoprotein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BKD, 2FMR, 2LA5, 2QND, 4OVA, 4QVZ, 4QW2, 5DE5, 5DE8, 5DEA
Band
Xq27.3 · X A7.1|X 34.83 cM
Bgee
caput epididymis · corpus epididymis · sural nerve · endothelial cell · Epithelium of choroid plexus
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Gene expression

Related conditions

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

FMR1

Nodes66
Edges65
Triples225
Avg. degree1.97
Density0.030303
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

FMR1

Top relations

Gene ontology · 115
FMR1 → anterograde axonal transport, axon, axon cytoplasm, axon terminus, Cajal body, cell junction, cell projection, cellular response to DNA damage stimulus, cellular response to hydroxyurea, cellular response to UV, cellular response to virus, central nervous system development, chromatin binding, chromocenter, chromosome, chromosome, centromeric region, cytoplasm, cytoplasmic ribonucleoprotein granule, cytoplasmic stress granule, cytosol
Bgee · 20
FMR1 → abdominal wall, Achilles tendon, caput epididymis, corpus epididymis, cumulus cell, endothelial cell, Epithelium of choroid plexus, epithelium of colon, Gonadal ridge, left lung lobe, mandibular prominence, migratory enteric neural crest cell, mucosa of paranasal sinus, pineal gland, retinal pigment epithelium, sural nerve, tail of epididymis, vas deferens, ventricular zone, white adipose tissue
RNA expression pattern · 20
FMR1 → abdominal wall, Achilles tendon, caput epididymis, corpus epididymis, cumulus cell, endothelial cell, Epithelium of choroid plexus, epithelium of colon, Gonadal ridge, left lung lobe, mandibular prominence, migratory enteric neural crest cell, mucosa of paranasal sinus, pineal gland, retinal pigment epithelium, sural nerve, tail of epididymis, vas deferens, ventricular zone, white adipose tissue
related to Gene expression · 14
FMR1 → American College, CGG, DNA, FMRP, Genomics, Higher, If, In, Medical Genetics, SMRT, The, The FMR1, This, Trinucleotide
related to Synaptic plasticity · 13
FMR1 → FMRP, FMRP-dependent, Fragile, Furthermore, Group, It, Messenger Ribonucleoprotein, Post-synaptic, Specifically, Studies, Synaptic, The, This
related to Fragile X syndrome · 8
FMR1 → Almost, As, CGG, Fewer, FMRP, In, These, Without
related to Interactions · 4
FMR1 → CYFIP1, CYFIP2, FXR1, NUFIP1
related to Polycystic ovarian syndrome · 3
FMR1 → PCOS, PCOS-like, The
related to Premature ovarian aging · 3
FMR1 → CGG, Minor, The FMR1
Band · 2
FMR1 → X A7.1|X 34.83 cM, Xq27.3

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fmrp gene protein fragile translation syndrome synaptic human mrna chromosome function mglur bp role synthesis messenger plasticity ovarian chr band

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FMR1AliasesFMR1, FMRP, FRAXA, POF, POF1, fragile X mental retardation 1, FMRP translational regulator 1, fragile X messenger ribonucleoprotein 11.00infobox
FMR1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2BKD, 2FMR, 2LA5, 2QND, 4OVA, 4QVZ, 4QW2, 5DE5, 5DE8, 5DEA1.00infobox
FMR1BandXq27.31.00infobox
FMR1BandX A7.1|X 34.83 cM1.00infobox
FMR1Bgeecaput epididymis1.00infobox
FMR1Bgeecorpus epididymis1.00infobox
FMR1Bgeesural nerve1.00infobox
FMR1Bgeeendothelial cell1.00infobox
FMR1BgeeEpithelium of choroid plexus1.00infobox
FMR1Bgeetail of epididymis1.00infobox
FMR1Bgeemucosa of paranasal sinus1.00infobox
FMR1Bgeeepithelium of colon1.00infobox
FMR1Bgeeretinal pigment epithelium1.00infobox
FMR1BgeeAchilles tendon1.00infobox
FMR1BgeeGonadal ridge1.00infobox
FMR1Bgeecumulus cell1.00infobox
FMR1Bgeewhite adipose tissue1.00infobox
FMR1Bgeevas deferens1.00infobox
FMR1Bgeeabdominal wall1.00infobox
FMR1Bgeemigratory enteric neural crest cell1.00infobox
FMR1Bgeeleft lung lobe1.00infobox
FMR1Bgeepineal gland1.00infobox
FMR1Bgeeventricular zone1.00infobox
FMR1Bgeemandibular prominence1.00infobox
FMR1BioGPSMore reference expression data1.00infobox
FMR1Chr.X chromosome (human)1.00infobox
FMR1Chr.X chromosome (mouse)1.00infobox
FMR1DatabasesNCBI: entry; OMA: entry1.00infobox
FMR1End147,951,125 bp1.00infobox
FMR1End67,761,569 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.