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PTGES3: Overview, Related Topics & Entities

Prostaglandin E synthase 3 (cytosolic) is a Prostaglandin E synthase enzyme that in humans is encoded by the PTGES3 gene.

Language: English [EN]
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PTGES3 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around PTGES3.

Related topics
6
Source areas
1
Connected nodes
7
Extracted relationships
100
Concept neighborhoods
8
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

5.3.99.3
Aliases
PTGES3, P23, TEBP, cPGES, prostaglandin E synthase 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJF
Band
12q13.3|12 · 10|10 D3
Bgee
secondary oocyte · bronchial epithelial cell · gonad · mucosa of sigmoid colon · caput epididymis
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PTGES3 connects Entity context

The extracted context around PTGES3 shows recurring relationship patterns in the source. For example, PTGES3 → chaperone binding, chaperone cofactor-dependent protein refolding, chaperone complex, chaperone-mediated protein complex assembly, cyclooxygenase pathway, cytoplasm, cytosol, DNA polymerase binding, extracellular exosome, fatty acid biosynthetic process, fatty acid metabolic process, Hsp90 protein binding, isomerase activity, lipid metabolism, nucleoplasm, nucleus, positive regulation of phosphorylation, positive regulation of telomerase activity, prostaglandin biosynthetic process, prostaglandin metabolic process Another extracted example is PTGES3 → abdominal wall, bronchial epithelial cell, caput epididymis, corpus epididymis, cumulus cell, embryo, endocardial cushion, epiblast, ganglionic eminence, gonad, Gonadal ridge, medullary collecting duct, migratory enteric neural crest cell, mucosa of sigmoid colon, primitive streak, renal corpuscle, secondary oocyte, trabecular bone, vas deferens, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

PTGES3

Top relations

Gene ontology · 35
PTGES3 → chaperone binding, chaperone cofactor-dependent protein refolding, chaperone complex, chaperone-mediated protein complex assembly, cyclooxygenase pathway, cytoplasm, cytosol, DNA polymerase binding, extracellular exosome, fatty acid biosynthetic process, fatty acid metabolic process, Hsp90 protein binding, isomerase activity, lipid metabolism, nucleoplasm, nucleus, positive regulation of phosphorylation, positive regulation of telomerase activity, prostaglandin biosynthetic process, prostaglandin metabolic process
Bgee · 20
PTGES3 → abdominal wall, bronchial epithelial cell, caput epididymis, corpus epididymis, cumulus cell, embryo, endocardial cushion, epiblast, ganglionic eminence, gonad, Gonadal ridge, medullary collecting duct, migratory enteric neural crest cell, mucosa of sigmoid colon, primitive streak, renal corpuscle, secondary oocyte, trabecular bone, vas deferens, ventricular zone
RNA expression pattern · 20
PTGES3 → abdominal wall, bronchial epithelial cell, caput epididymis, corpus epididymis, cumulus cell, embryo, endocardial cushion, epiblast, ganglionic eminence, gonad, Gonadal ridge, medullary collecting duct, migratory enteric neural crest cell, mucosa of sigmoid colon, primitive streak, renal corpuscle, secondary oocyte, trabecular bone, vas deferens, ventricular zone
Band · 2
PTGES3 → 10|10 D3, 12q13.3|12
Chr. · 2
PTGES3 → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
PTGES3 → 127,913,141 bp, 56,688,408 bp
5.3.99.3 · 1
PTGES3 → ↗
Aliases · 1
PTGES3 → PTGES3, P23, TEBP, cPGES, prostaglandin E synthase 3
Available structures · 1
PTGES3 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJF
BioGPS · 1
PTGES3 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band chromosome 12 prostaglandin synthase location encoded enzyme chaperone mouse protein p23 search activity 688 408

PTGES3 relationships Subject–Predicate–Object triples

TTTA extracted 100 structured relationships around PTGES3. Examples in this analysis include PTGES3 → 5.3.99.3 → ↗ and PTGES3 → Aliases → PTGES3, P23, TEBP, cPGES, prostaglandin E synthase 3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PTGES35.3.99.31.00infobox
PTGES3AliasesPTGES3, P23, TEBP, cPGES, prostaglandin E synthase 31.00infobox
PTGES3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1EJF1.00infobox
PTGES3Band12q13.3|121.00infobox
PTGES3Band10|10 D31.00infobox
PTGES3Bgeesecondary oocyte1.00infobox
PTGES3Bgeebronchial epithelial cell1.00infobox
PTGES3Bgeegonad1.00infobox
PTGES3Bgeemucosa of sigmoid colon1.00infobox
PTGES3Bgeecaput epididymis1.00infobox
PTGES3Bgeeventricular zone1.00infobox
PTGES3Bgeeembryo1.00infobox
PTGES3Bgeeganglionic eminence1.00infobox
PTGES3Bgeecorpus epididymis1.00infobox
PTGES3Bgeetrabecular bone1.00infobox
PTGES3Bgeeabdominal wall1.00infobox
PTGES3Bgeemedullary collecting duct1.00infobox
PTGES3Bgeerenal corpuscle1.00infobox
PTGES3BgeeGonadal ridge1.00infobox
PTGES3Bgeeendocardial cushion1.00infobox
PTGES3Bgeecumulus cell1.00infobox
PTGES3Bgeeprimitive streak1.00infobox
PTGES3Bgeevas deferens1.00infobox
PTGES3Bgeemigratory enteric neural crest cell1.00infobox
PTGES3Bgeeepiblast1.00infobox
PTGES3BioGPSn/a1.00infobox
PTGES3Chr.Chromosome 12 (human)1.00infobox
PTGES3Chr.Chromosome 10 (mouse)1.00infobox
PTGES3DatabasesNCBI: entry; OMA: entry1.00infobox
PTGES3End56,688,408 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PTGES3 bring nearby vocabulary together. In this analysis, examples include Synthase, Activity and Search. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Prostaglandin
    • Ptges3
    • Synthase
    • Chromosome
    • Human
    • Bp
    • Chr
    • Activity
    • Chaperone
    • End
    • Mouse
  • chaperone
    • Protein
    • Functioning
    • Functions
    • Glucocorticoid
    • Known
    • Proper
    • Receptors
    • Required
    • Steroid
    • Gene
    • Activity
    • Encoded
  • prostaglandin e synthase
    • Prostaglandin
    • Ptges3
    • Synthase
    • Activity
    • Enzyme
    • Search
    • Gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • PTGES3
    • Synthase
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Reading
    • References
    • Chaperone
    • End
  • ptges3
    • Synthase
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Reading
    • References
    • Chaperone
    • End
  • enzyme
    • Prostaglandin
    • Ptges3
    • Synthase
    • Humans
    • Reading
    • References
    • Gene
    • Activity
    • Encoded
    • P23
    • Search
    • Location
  • steroid receptors
    • Also
    • Functioning
    • Functions
    • Glucocorticoid
    • Known
    • Proper
    • Receptors
    • Required
    • Steroid
    • Chaperone
    • Encoded
    • P23
  • glucocorticoid
    • Known
    • Proper
    • Receptors
    • Required
    • Steroid
    • P23
    • Protein

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the PTGES3 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

PTGES3

Nodes8
Edges7
Triples100
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around PTGES3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PTGES3 · EN edition · Analysis: TopicsToTalkAbout

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