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Organic anion transporter family

Members of the Organic Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the…

Function, Pharmacology & Homology

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AlphaFold
IPR004156 · PF03137
Available protein structures:
IPR004156 · PF03137
InterPro
IPR004156
PDB
IPR004156 PF03137 (ECOD; PDBsum)
Pfam
PF03137
Symbol
OATP

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Function

Homology

Pharmacology

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Map overview Semantic statistics

Organic anion transporter family

Nodes35
Edges34
Triples11
Avg. degree1.94
Density0.057143
Components1

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Organic anion transporter family

Top relations

AlphaFold · 2
Organic anion transporter family → IPR004156, PF03137
Available protein structures: · 2
Organic anion transporter family → IPR004156, PF03137
InterPro · 1
Organic anion transporter family → IPR004156
PDB · 1
Organic anion transporter family → IPR004156 PF03137 (ECOD; PDBsum)
Pfam · 1
Organic anion transporter family → PF03137
Symbol · 1
Organic anion transporter family → OATP
TCDB · 1
Organic anion transporter family → 2.A.60

Important terminology Word statistics

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Important terminology

oatps family transport drugs anion oat membrane oatp1b1 well also organic present cell human proteins oatp animal members anions basolateral

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Organic anion transporter familyAlphaFoldIPR0041561.00infobox
Organic anion transporter familyAlphaFoldPF031371.00infobox
Organic anion transporter familyAvailable protein structures:IPR0041561.00infobox
Organic anion transporter familyAvailable protein structures:PF031371.00infobox
Organic anion transporter familyInterProIPR0041561.00infobox
Organic anion transporter familyPDBIPR004156 PF03137 (ECOD; PDBsum)1.00infobox
Organic anion transporter familyPfamPF031371.00infobox
Organic anion transporter familySymbolOATP1.00infobox
Organic anion transporter familyTCDB2.A.601.00infobox
thyroidinstance ofthyroid hormones and quinolones.Organic anion transporting polypeptides carry bile acids as well as bilirubin and numerous hormones0.80text
steroid hormones across the basolateral membraneinstance ofthyroid hormones and quinolones.Organic anion transporting polypeptides carry bile acids as well as bilirubin and numerous hormones0.80text

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