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EPS8

Epidermal growth factor receptor kinase substrate 8 is an enzyme that in humans is encoded by the EPS8 gene.

Interactions, Function & Clinical significance

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Interactions

8 related topics

Function

4 related topics

Clinical significance

1 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
EPS8, DFNB102, epidermal growth factor receptor pathway substrate 8
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E8M
Band
12p12.3 · 6 G1|6 66.78 cM
Bgee
jejunal mucosa · mucosa of sigmoid colon · Achilles tendon · cartilage tissue · corpus epididymis
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 6 (mouse)

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Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

EPS8

Nodes20
Edges19
Triples122
Avg. degree1.9
Density0.1
Components1

How this topic connects Entity context

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EPS8

Top relations

Gene ontology · 43
EPS8 → actin binding, actin crosslink formation, actin cytoskeleton reorganization, actin filament bundle assembly, actin polymerization-dependent cell motility, adult locomotory behavior, barbed-end actin filament capping, behavioral response to ethanol, brush border, cell cortex, cell junction, cell population proliferation, cell projection, cellular response to leukemia inhibitory factor, cytoplasm, dendritic cell migration, epidermal growth factor receptor signaling pathway, exit from mitosis, extracellular exosome, glutamatergic synapse
Bgee · 20
EPS8 → Achilles tendon, cartilage tissue, conjunctival fornix, corpus epididymis, ileum, jejunal mucosa, left colon, migratory enteric neural crest cell, mucosa of sigmoid colon, parotid gland, pericardium, popliteal artery, primary oocyte, right kidney, secondary oocyte, seminal vesicula, synovial joint, tail of epididymis, tibial arteries, zygote
RNA expression pattern · 20
EPS8 → Achilles tendon, cartilage tissue, conjunctival fornix, corpus epididymis, ileum, jejunal mucosa, left colon, migratory enteric neural crest cell, mucosa of sigmoid colon, parotid gland, pericardium, popliteal artery, primary oocyte, right kidney, secondary oocyte, seminal vesicula, synovial joint, tail of epididymis, tibial arteries, zygote
related to Function · 9
EPS8 → Alternate, EGFR, Highly, It, PH, Rac, Ras, SH3, This
related to Interactions · 5
EPS8 → ABI1, BAIAP2, DVL1, SHB, SHC1SOS1
Band · 2
EPS8 → 12p12.3, 6 G1|6 66.78 cM
Chr. · 2
EPS8 → Chromosome 12 (human), Chromosome 6 (mouse)
End · 2
EPS8 → 137,631,874 bp, 15,882,329 bp
Aliases · 1
EPS8 → EPS8, DFNB102, epidermal growth factor receptor pathway substrate 8
Available structures · 1
EPS8 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E8M

Important terminology Word statistics

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Important terminology

bp gene chr human band growth chromosome 12 epidermal factor receptor location pathway mouse substrate function search 882 329 end

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
EPS8AliasesEPS8, DFNB102, epidermal growth factor receptor pathway substrate 81.00infobox
EPS8Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E8M1.00infobox
EPS8Band12p12.31.00infobox
EPS8Band6 G1|6 66.78 cM1.00infobox
EPS8Bgeejejunal mucosa1.00infobox
EPS8Bgeemucosa of sigmoid colon1.00infobox
EPS8BgeeAchilles tendon1.00infobox
EPS8Bgeecartilage tissue1.00infobox
EPS8Bgeecorpus epididymis1.00infobox
EPS8Bgeepericardium1.00infobox
EPS8Bgeetail of epididymis1.00infobox
EPS8Bgeepopliteal artery1.00infobox
EPS8Bgeetibial arteries1.00infobox
EPS8Bgeesynovial joint1.00infobox
EPS8Bgeesecondary oocyte1.00infobox
EPS8Bgeeleft colon1.00infobox
EPS8Bgeezygote1.00infobox
EPS8Bgeeseminal vesicula1.00infobox
EPS8Bgeemigratory enteric neural crest cell1.00infobox
EPS8Bgeeprimary oocyte1.00infobox
EPS8Bgeeileum1.00infobox
EPS8Bgeeconjunctival fornix1.00infobox
EPS8Bgeeright kidney1.00infobox
EPS8Bgeeparotid gland1.00infobox
EPS8BioGPSMore reference expression data1.00infobox
EPS8Chr.Chromosome 12 (human)1.00infobox
EPS8Chr.Chromosome 6 (mouse)1.00infobox
EPS8DatabasesNCBI: entry; OMA: entry1.00infobox
EPS8End15,882,329 bp1.00infobox
EPS8End137,631,874 bp1.00infobox

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