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Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis of cancer cells to other locations…
The analysis highlights Art and Regions as prominent areas in the source structure around Endoglin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Endoglin shows recurring relationship patterns in the source. For example, Endoglin → activin binding, angiogenesis, artery morphogenesis, atrial cardiac muscle tissue morphogenesis, atrioventricular canal morphogenesis, BMP binding, BMP signaling pathway, bone development, branching involved in blood vessel morphogenesis, cardiac atrium morphogenesis, cardiac ventricle morphogenesis, cell adhesion, cell chemotaxis, cell migration, cell migration involved in endocardial cushion formation, cell motility, cell surface, cellular response to mechanical stimulus, central nervous system vasculogenesis, detection of hypoxia Another extracted example is Endoglin → ankle joint, apex of heart, ascending aorta, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, Descending thoracic aorta, external carotid artery, Ileal epithelium, internal carotid artery, lactiferous gland, left ovary, right auricle of heart, right coronary artery, right lobe of thyroid gland, right lung, right lung lobe, right ovary, right ventricle, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
beta tgf receptor cells gene human expression bp cancer cell role binding extracellular complex growth band domain chr tumor chromosome
TTTA extracted 193 structured relationships around Endoglin. Examples in this analysis include Endoglin → Aliases → ENG, Eng, AI528660, AI662476, CD105, Endo, S-endoglin, END, HHT1, ORW1, endoglin and Endoglin → Band → 9q34.11. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Endoglin | Aliases | ENG, Eng, AI528660, AI662476, CD105, Endo, S-endoglin, END, HHT1, ORW1, endoglin | 1.00 | infobox |
| Endoglin | Band | 9q34.11 | 1.00 | infobox |
| Endoglin | Band | 2 B|2 22.09 cM | 1.00 | infobox |
| Endoglin | Bgee | right lung | 1.00 | infobox |
| Endoglin | Bgee | right auricle of heart | 1.00 | infobox |
| Endoglin | Bgee | apex of heart | 1.00 | infobox |
| Endoglin | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| Endoglin | Bgee | left ovary | 1.00 | infobox |
| Endoglin | Bgee | right ovary | 1.00 | infobox |
| Endoglin | Bgee | right coronary artery | 1.00 | infobox |
| Endoglin | Bgee | upper lobe of left lung | 1.00 | infobox |
| Endoglin | Bgee | ascending aorta | 1.00 | infobox |
| Endoglin | Bgee | Descending thoracic aorta | 1.00 | infobox |
| Endoglin | Bgee | lactiferous gland | 1.00 | infobox |
| Endoglin | Bgee | ankle joint | 1.00 | infobox |
| Endoglin | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| Endoglin | Bgee | cardiac muscle tissue of left ventricle | 1.00 | infobox |
| Endoglin | Bgee | right lung lobe | 1.00 | infobox |
| Endoglin | Bgee | external carotid artery | 1.00 | infobox |
| Endoglin | Bgee | Ileal epithelium | 1.00 | infobox |
| Endoglin | Bgee | internal carotid artery | 1.00 | infobox |
| Endoglin | Bgee | right ventricle | 1.00 | infobox |
| Endoglin | BioGPS | More reference expression data | 1.00 | infobox |
| Endoglin | Chr. | Chromosome 9 (human) | 1.00 | infobox |
| Endoglin | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| Endoglin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Endoglin | End | 127,854,658 bp | 1.00 | infobox |
| Endoglin | End | 32,572,681 bp | 1.00 | infobox |
| Endoglin | Ensembl | ENSG00000106991 | 1.00 | infobox |
| Endoglin | Entrez | 2022 | 1.00 | infobox |
The concept neighborhoods around Endoglin bring nearby vocabulary together. In this analysis, examples include Beta, Tgf and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Endoglin, one of the stronger structural bridges in this analysis connects Endoglin with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Endoglin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Endoglin · EN edition · Analysis: TopicsToTalkAbout