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Bone morphogenetic protein 7

Bone morphogenetic protein 7 or BMP7 (also known as osteogenic protein-1 or OP-1) is a protein that in humans is encoded by the BMP7 gene.

Applications, Function & Therapeutic application

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Function

13 related topics

Therapeutic application

3 related topics

Promotion of brown fat

1 related topics

Overview

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Key facts & relationships

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Aliases
BMP7, OP-1, bone morphogenetic protein 7
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U
Band
20q13.31 · 2 H3|2 95.54 cM
Bgee
retinal pigment epithelium · ventricular zone · optic nerve · ganglionic eminence · olfactory bulb
BioGPS
n/a
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

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Overview

Function

Therapeutic application

Promotion of brown fat

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Map overview Semantic statistics

Bone morphogenetic protein 7

Nodes24
Edges23
Triples173
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

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Bone morphogenetic protein 7

Top relations

Gene ontology · 105
Bone morphogenetic protein 7 → allantois development, anatomical structure formation involved in morphogenesis, animal organ morphogenesis, axon guidance, BMP receptor binding, BMP signaling pathway, branching involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, camera-type eye morphogenesis, cardiac muscle tissue development, cardiac septum morphogenesis, cartilage development, cell development, cell differentiation, cellular response to BMP stimulus, cellular response to hypoxia, chorio-allantoic fusion, collagen-containing extracellular matrix, cytokine activity, dendrite development
Bgee · 19
Bone morphogenetic protein 7 → allantois, buccal mucosa cell, ganglionic eminence, genital tubercle, left lobe of thyroid gland, lip, molar, mucosa of esophagus, neural fold, neural groove, olfactory bulb, optic nerve, renal corpuscle, retinal pigment epithelium, right lobe of thyroid gland, surface ectoderm, thyroid gland, transitional epithelium of urinary bladder, ventricular zone
RNA expression pattern · 19
Bone morphogenetic protein 7 → allantois, buccal mucosa cell, ganglionic eminence, genital tubercle, left lobe of thyroid gland, lip, molar, mucosa of esophagus, neural fold, neural groove, olfactory bulb, optic nerve, renal corpuscle, retinal pigment epithelium, right lobe of thyroid gland, surface ectoderm, thyroid gland, transitional epithelium of urinary bladder, ventricular zone
related to External links · 7
Bone morphogenetic protein 7 → BMP7, Medicine Medical Subject Headings, MeSH, Molecule, National Library, UCSC Genome Browser, Year
Band · 2
Bone morphogenetic protein 7 → 2 H3|2 95.54 cM, 20q13.31
Chr. · 2
Bone morphogenetic protein 7 → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
Bone morphogenetic protein 7 → 172,782,114 bp, 57,266,641 bp
Aliases · 1
Bone morphogenetic protein 7 → BMP7, OP-1, bone morphogenetic protein 7
Available structures · 1
Bone morphogenetic protein 7 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U
BioGPS · 1
Bone morphogenetic protein 7 → n/a

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Important terminology

bmp7 human bone protein bp gene also chr band fibrosis kidney treatment bmp-7 emt chromosome 20 morphogenetic location development expression

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Bone morphogenetic protein 7AliasesBMP7, OP-1, bone morphogenetic protein 71.00infobox
Bone morphogenetic protein 7Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U1.00infobox
Bone morphogenetic protein 7Band20q13.311.00infobox
Bone morphogenetic protein 7Band2 H3|2 95.54 cM1.00infobox
Bone morphogenetic protein 7Bgeeretinal pigment epithelium1.00infobox
Bone morphogenetic protein 7Bgeeventricular zone1.00infobox
Bone morphogenetic protein 7Bgeeoptic nerve1.00infobox
Bone morphogenetic protein 7Bgeeganglionic eminence1.00infobox
Bone morphogenetic protein 7Bgeeolfactory bulb1.00infobox
Bone morphogenetic protein 7Bgeethyroid gland1.00infobox
Bone morphogenetic protein 7Bgeeleft lobe of thyroid gland1.00infobox
Bone morphogenetic protein 7Bgeeright lobe of thyroid gland1.00infobox
Bone morphogenetic protein 7Bgeebuccal mucosa cell1.00infobox
Bone morphogenetic protein 7Bgeemucosa of esophagus1.00infobox
Bone morphogenetic protein 7Bgeemolar1.00infobox
Bone morphogenetic protein 7Bgeeallantois1.00infobox
Bone morphogenetic protein 7Bgeelip1.00infobox
Bone morphogenetic protein 7Bgeetransitional epithelium of urinary bladder1.00infobox
Bone morphogenetic protein 7Bgeesurface ectoderm1.00infobox
Bone morphogenetic protein 7Bgeegenital tubercle1.00infobox
Bone morphogenetic protein 7Bgeeneural groove1.00infobox
Bone morphogenetic protein 7Bgeeneural fold1.00infobox
Bone morphogenetic protein 7Bgeerenal corpuscle1.00infobox
Bone morphogenetic protein 7BioGPSn/a1.00infobox
Bone morphogenetic protein 7Chr.Chromosome 20 (human)1.00infobox
Bone morphogenetic protein 7Chr.Chromosome 2 (mouse)1.00infobox
Bone morphogenetic protein 7DatabasesNCBI: entry; OMA: entry1.00infobox
Bone morphogenetic protein 7End57,266,641 bp1.00infobox
Bone morphogenetic protein 7End172,782,114 bp1.00infobox
Bone morphogenetic protein 7EnsemblENSG000001011441.00infobox

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