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Explore the main themes, entities and connections around GDF2. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Function
22 related topics
Interactions
8 related topics
Signaling
8 related topics
Associated diseases
3 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- Aliases
- GDF2, BMP-9, BMP9, HHT5, growth differentiation factor 2
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZKZ, 4FAO, 4MPL, 4YCG, 4YCI
- Band
- 10q11.22 · 14|14 B
- Bgee
- testicle · right lobe of liver · placenta · atrium · right atrium
- BioGPS
- n/a
- Chr.
- Chromosome 10 (human) · Chromosome 14 (mouse)
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Structure
Function
- Basal forebrain
- Neurons Neuron
- Neurotransmitter
- Acetylcholine
- Learning
- Memory
- Attention
- Hepcidin
- Cationic Cation
- Antimicrobial
- Liver
- Hepatocytes Hepatocyte
- Iron metabolism
- Physiological
- Endothelial
- Endoglin
- Hereditary hemorrhagic telangiectasia
- BMP3 Bone morphogenetic protein 3
- Mesenchymal stem cells
- Smad SMAD (protein)
- HEY1
- RUNX2
Interactions
Associated diseases
- Pulmonary arterial hypertension (PAH) Pulmonary arterial hypertension
- Congenital heart disease Congenital heart defect
- Hemoptysis
Signaling
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.GDF2
Nodes54
Edges53
Triples160
Avg. degree1.96
Density0.037037
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
GDF2
Top relations
Gene ontology · 42
GDF2 → activin receptor signaling pathway, angiogenesis, blood vessel morphogenesis, BMP signaling pathway, branching involved in blood vessel morphogenesis, cartilage development, cell development, cellular iron ion homeostasis, cellular response to BMP stimulus, cytokine activity, extracellular exosome, extracellular region, extracellular space, growth factor activity, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, negative regulation of cell growth, negative regulation of DNA biosynthetic process, negative regulation of DNA replication, negative regulation of endothelial cell migration
Bgee · 20
GDF2 → abdominal wall, atrioventricular junction, atrium, autopod region, calvaria, embryo, fetal liver hematopoietic progenitor cell, haematopoietic system, hepatobiliary system, hypothalamus, left lobe of liver, left ventricle, liver, mesenteric lymph nodes, placenta, right atrium, right auricle of heart, right lobe of liver, testicle, ventricle of the heart
RNA expression pattern · 20
GDF2 → abdominal wall, atrioventricular junction, atrium, autopod region, calvaria, embryo, fetal liver hematopoietic progenitor cell, haematopoietic system, hepatobiliary system, hypothalamus, left lobe of liver, left ventricle, liver, mesenteric lymph nodes, placenta, right atrium, right auricle of heart, right lobe of liver, testicle, ventricle of the heart
related to Interactions · 16
GDF2 → Activin, ActRIIA, ActRIIB, ACVR1, ALK1, ALK1-7, ALK2, BMP, BMP10, BMPRII, BMPs, II, In, TGF-β, The, This
related to Signaling · 13
GDF2 → Another, BMPs, ERK, HCC, JNK, Like, Little, MPCs, R-Smads, Smad, Smad-2/Smad-3, Smad1, The
related to Function · 12
GDF2 → ACVRL1, ALK1, Another, BFCN, BMP3, BMPs, Endoglin, GDF2/BMP-9, HHT, Mutations, TGF-beta, The
related to Associated diseases · 6
GDF2 → Congenital, In, Most, Mutations, PAH, Pathogenic
related to Structure · 3
GDF2 → BMP9, C-terminal, N-terminal TGF-beta-like
Band · 2
GDF2 → 10q11.22, 14|14 B
Chr. · 2
GDF2 → Chromosome 10 (human), Chromosome 14 (mouse)
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
factor differentiation growth bp human type gene chr band also receptor pathway ii alk1 signaling cells chromosome 10 bmps affinity
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| GDF2 | Aliases | GDF2, BMP-9, BMP9, HHT5, growth differentiation factor 2 | 1.00 | infobox |
| GDF2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZKZ, 4FAO, 4MPL, 4YCG, 4YCI | 1.00 | infobox |
| GDF2 | Band | 10q11.22 | 1.00 | infobox |
| GDF2 | Band | 14|14 B | 1.00 | infobox |
| GDF2 | Bgee | testicle | 1.00 | infobox |
| GDF2 | Bgee | right lobe of liver | 1.00 | infobox |
| GDF2 | Bgee | placenta | 1.00 | infobox |
| GDF2 | Bgee | atrium | 1.00 | infobox |
| GDF2 | Bgee | right atrium | 1.00 | infobox |
| GDF2 | Bgee | right auricle of heart | 1.00 | infobox |
| GDF2 | Bgee | haematopoietic system | 1.00 | infobox |
| GDF2 | Bgee | hypothalamus | 1.00 | infobox |
| GDF2 | Bgee | ventricle of the heart | 1.00 | infobox |
| GDF2 | Bgee | left ventricle | 1.00 | infobox |
| GDF2 | Bgee | hepatobiliary system | 1.00 | infobox |
| GDF2 | Bgee | liver | 1.00 | infobox |
| GDF2 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| GDF2 | Bgee | embryo | 1.00 | infobox |
| GDF2 | Bgee | left lobe of liver | 1.00 | infobox |
| GDF2 | Bgee | autopod region | 1.00 | infobox |
| GDF2 | Bgee | atrioventricular junction | 1.00 | infobox |
| GDF2 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| GDF2 | Bgee | abdominal wall | 1.00 | infobox |
| GDF2 | Bgee | calvaria | 1.00 | infobox |
| GDF2 | BioGPS | n/a | 1.00 | infobox |
| GDF2 | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| GDF2 | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
| GDF2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| GDF2 | End | 47,327,588 bp | 1.00 | infobox |
| GDF2 | End | 33,669,155 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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