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DRIP-seq (DRIP-sequencing) is a technology for genome-wide profiling of a type of DNA-RNA hybrid called an "R-loop". DRIP-seq utilizes a sequence-independent but structure-specific antibody for DNA-RNA immunoprecipitation (DRIP) to capture R-loops for massively parallel DNA sequencing.
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r-loops r-loop dna dna-rna sequencing immunoprecipitation used s9 regions mab formation gdna methods profiling genome antibody hybrids also relies fragments
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| DRIP-seq | is a | rapid obtention of the data | 0.90 | text |
| AID | instance of | R-loops can cause genome instability by exposing single-stranded DNA to endogenous damages exerted by the action of enzymes | 0.80 | text |
| APOBEC | instance of | R-loops can cause genome instability by exposing single-stranded DNA to endogenous damages exerted by the action of enzymes | 0.80 | text |
| or overexposure to chemically reactive species | instance of | R-loops can cause genome instability by exposing single-stranded DNA to endogenous damages exerted by the action of enzymes | 0.80 | text |
| DRIP-seq | has method | Although | 0.60 | section |
| DRIP-seq | has method | R-loop | 0.60 | section |
| DRIP-seq | has method | Non-denaturing | 0.60 | section |
| DRIP-seq | has method | This | 0.60 | section |
| DRIP-seq | has method | CpG | 0.60 | section |
| DRIP-seq | has method | R-loops | 0.60 | section |
| DRIP-seq | has method | DNA | 0.60 | section |
| DRIP-seq | has method | RNA In Vitro Enrichment | 0.60 | section |
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