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APOBEC: Members, Family members & Function

APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases.

Language: English [EN]
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APOBEC topic overview

The analysis highlights Members, Family members and Function as prominent areas in the source structure around APOBEC.

Related topics
19
Source areas
4
Connected nodes
27
Extracted relationships
43
Concept neighborhoods
9
Bridge connections
27

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Family members · 11 topics
Function · 6 topics
Overview · 1 topics
Structure · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR013158 · PF08210
Available protein structures:
IPR013158 · PF08210
InterPro
IPR013158
PDB
IPR013158 PF08210 (ECOD; PDBsum)
Pfam
PF08210
Symbol
APOBEC_N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Structure

Family members

Bibliography

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How APOBEC connects Entity context

The extracted context around APOBEC shows recurring relationship patterns in the source. For example, APOBEC → APOBEC-1, APOBEC-like, APOBEC-modified, C-terminal, CAA, CGA, For, In, More, NF1, RNA, RNA-binding, The, The APOBEC, The N-terminal, UAA, UGA Another extracted example is APOBEC → APOBEC3, April, Gazzo, Gupta, Nature Genetics, Selenica. Use these groups to spot repeated connection types before inspecting the individual relationships.

APOBEC

Top relations

related to Function · 17
APOBEC → APOBEC-1, APOBEC-like, APOBEC-modified, C-terminal, CAA, CGA, For, In, More, NF1, RNA, RNA-binding, The, The APOBEC, The N-terminal, UAA, UGA
related to Bibliography · 6
APOBEC → APOBEC3, April, Gazzo, Gupta, Nature Genetics, Selenica
related to Family members · 5
APOBEC → AID, APOBEC1APOBEC2APOBEC3AAPOBEC3BAPOBEC3CAPOBEC3D, APOBEC3E, APOBEC3FAPOBEC3GAPOBEC3HAPOBEC4Activation-induced, Human
related to Cancer · 3
APOBEC → These, This, When
related to Structure · 3
APOBEC → APOBEC3, APOBEC3G's, Many
AlphaFold · 2
APOBEC → IPR013158, PF08210
Available protein structures: · 2
APOBEC → IPR013158, PF08210
InterPro · 1
APOBEC → IPR013158
PDB · 1
APOBEC → IPR013158 PF08210 (ECOD; PDBsum)
Pfam · 1
APOBEC → PF08210

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

proteins mrna family catalytic cytidine editing cancer protein domain apolipoprotein structure members modifications zinc deaminase deamination rna apobec-1 intestinal interacts

APOBEC relationships Subject–Predicate–Object triples

TTTA extracted 43 structured relationships around APOBEC. Examples in this analysis include APOBEC → AlphaFold → IPR013158 and APOBEC → AlphaFold → PF08210. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
APOBECAlphaFoldIPR0131581.00infobox
APOBECAlphaFoldPF082101.00infobox
APOBECAvailable protein structures:IPR0131581.00infobox
APOBECAvailable protein structures:PF082101.00infobox
APOBECInterProIPR0131581.00infobox
APOBECPDBIPR013158 PF08210 (ECOD; PDBsum)1.00infobox
APOBECPfamPF082101.00infobox
APOBECSymbolAPOBEC_N1.00infobox
in the site-specific deamination of a CGA to a UGA stop codon in neurofibromatosis type 1instance ofFor other APOBEC-modified transcripts0.80text
APOBECrelated to BibliographyGupta0.60section
APOBECrelated to BibliographyGazzo0.60section
APOBECrelated to BibliographySelenica0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around APOBEC bring nearby vocabulary together. In this analysis, examples include Family, Proteins and Cytidine. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • APOBEC
    • Family
    • Proteins
    • Cytidine
    • Mrna
    • Cells
    • Expressed
    • Human
    • Members
    • Protein
    • Tumor
    • Widely
    • Cancer
  • apobec
    • Family
    • Proteins
    • Cytidine
    • Mrna
    • Cells
    • Expressed
    • Human
    • Members
    • Protein
    • Tumor
    • Widely
    • Cancer
  • family members
    • Protein
    • References
    • Cytidine
    • Apobec3
    • Deaminase
    • Human
    • Structure
    • Widely
    • Mrna
    • Cells
    • Members
    • Cancer
  • mrna
    • Codon
    • Intestinal
    • Resulting
    • Stop
    • Structure
    • Family
    • Cytidine
    • Bibliography
    • Conserved
    • Deaminases
    • Evolutionarily
    • Function
  • cytidine deaminases
    • Enzyme
    • Evolutionarily
    • Polypeptide
    • Deaminase
    • Family
    • Editing
    • Deaminases
    • Mrna
    • Apobec3
    • Deamination
    • Human
    • Members
  • activation-induced (cytidine) deaminase
    • Deaminase
    • Family
    • Apobec3
    • Deamination
    • Human
    • Members
    • Protein
    • Widely
    • Zinc
    • Deaminases
    • Domain
    • Enzyme
  • structure
    • Bibliography
    • Function
    • References
    • Codon
    • Interacts
    • Intestinal
    • Members
    • Mrna
    • Protein
    • Resulting
    • Stop
    • Cancer
  • bibliography
    • Function
    • References
    • Members
    • Protein
    • Structure
    • Cancer
    • Editing
    • Mrna
    • Family

Connections between topic areas Semantic bridges

For APOBEC, one of the stronger structural bridges in this analysis connects APOBEC with Family members. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
APOBECFamily members · splits 16 ⟂ 12
APOBECFunction · splits 21 ⟂ 7
APOBECBibliography · splits 24 ⟂ 4

Map overview Semantic statistics

APOBEC

Nodes28
Edges27
Triples43
Avg. degree1.93
Density0.071429
Components1

Source & methodology

TTTA analyzes the structure around APOBEC to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members, Family members & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — APOBEC · EN edition · Analysis: TopicsToTalkAbout

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