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Long-term potentiation

In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity. These are patterns of synaptic activity that produce a long-lasting increase in signal transmission between two neurons. The opposite of LTP is long-term depression, which produces a long-lasting decrease in synaptic strength.

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Relationship to behavioral memory

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Long-term potentiation

Nodes121
Edges120
Triples14
Avg. degree1.98
Density0.016529
Components1

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Long-term potentiation

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related to Relationship to behavioral memory · 4
Long-term potentiation → Because, For, LTP, While

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ltp synaptic may protein synthesis postsynaptic learning cell synapses memory hippocampus one also l-ltp activity expression stimuli nmda hypothesis potentiation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BCM Theoryinstance ofMathematical models0.80text
which depends also on intracellular calcium in relation to NMDA receptor voltage gatesinstance ofMathematical models0.80text
have been developed since the 1980sinstance ofMathematical models0.80text
modify the traditional a priori Hebbian learning model with both biologicalinstance ofMathematical models0.80text
experimental justificationinstance ofMathematical models0.80text
CREBinstance ofThese cytoplasmic and nuclear molecules may include transcription factors0.80text
axonal boutoninstance oftherefore more crucial than each molecule individually is the interaction between them in the maintenance of L-LTP.The long-term stabilization of synaptic changes is also determ…0.80text
dendritic spineinstance oftherefore more crucial than each molecule individually is the interaction between them in the maintenance of L-LTP.The long-term stabilization of synaptic changes is also determ…0.80text
postsynaptic densityinstance oftherefore more crucial than each molecule individually is the interaction between them in the maintenance of L-LTP.The long-term stabilization of synaptic changes is also determ…0.80text
norepinephrine may alter the protein synthesis-dependent late phase of LTPinstance ofβ-adrenergic receptor agonists0.80text
Long-term potentiationrelated to Relationship to behavioral memoryWhile0.60section
Long-term potentiationrelated to Relationship to behavioral memoryLTP0.60section

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