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Dofetilide is a class III antiarrhythmic agent. It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 μg of dofetilide. It is not available in Europe or Australia.
The analysis highlights Applications, Regions and Measurement as prominent areas in the source structure around Dofetilide.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Dofetilide shows recurring relationship patterns in the source. For example, Dofetilide → After, Arrhythmias, Based, Because, CHF-related, Danish Investigations, DIAMOND, Europe, LV, Mortality, Pfizer Another extracted example is Dofetilide → After, If, Prior, QT, QTc. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cyp3a4 individuals qtc available however dose atrial fibrillation patients first qt torsades de pointes three days 500 creatinine drugs oral
TTTA extracted 51 structured relationships around Dofetilide. Examples in this analysis include Dofetilide → 3D model (JSmol) → Interactive image and Dofetilide → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Dofetilide | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Dofetilide | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Dofetilide | ATC code | C01BD04 (WHO) | 1.00 | infobox |
| Dofetilide | Bioavailability | 96% (oral) | 1.00 | infobox |
| Dofetilide | CAS Number | 115256-11-6 Y | 1.00 | infobox |
| Dofetilide | ChEBI | CHEBI:4681 Y | 1.00 | infobox |
| Dofetilide | ChEMBL | ChEMBL473 Y | 1.00 | infobox |
| Dofetilide | ChemSpider | 64435 Y | 1.00 | infobox |
| Dofetilide | CompTox Dashboard (EPA) | DTXSID5046433 | 1.00 | infobox |
| Dofetilide | DrugBank | DB00204 Y | 1.00 | infobox |
| Dofetilide | ECHA InfoCard | 100.166.441 | 1.00 | infobox |
| Dofetilide | Elimination half-life | 10 hours | 1.00 | infobox |
| Dofetilide | Formula | C19H27N3O5S2 | 1.00 | infobox |
| Dofetilide | IUPHAR/BPS | 2604 | 1.00 | infobox |
| Dofetilide | KEGG | D00647 Y | 1.00 | infobox |
| Dofetilide | MedlinePlus | a601235 | 1.00 | infobox |
| Dofetilide | Molar mass | 441.56 g·mol−1 | 1.00 | infobox |
| Dofetilide | Protein binding | 60% -70% | 1.00 | infobox |
| Dofetilide | PubChem CID | 71329 | 1.00 | infobox |
| Dofetilide | Trade names | Tikosyn | 1.00 | infobox |
| Dofetilide | UNII | R4Z9X1N2ND | 1.00 | infobox |
| Dofetilide | causes | an increased rate of potentially life-threatening arrhythmias in comparison to other therapies | 0.90 | text |
| Dofetilide | is a | class III antiarrhythmic agent | 0.90 | text |
The concept neighborhoods around Dofetilide bring nearby vocabulary together. In this analysis, examples include Cyp3a4, However and Individuals. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Dofetilide, one of the stronger structural bridges in this analysis connects Dofetilide with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Dofetilide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Regions & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Dofetilide · EN edition · Analysis: TopicsToTalkAbout