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Exportin 1 (XPO1), also known as chromosomal region maintenance 1 (CRM1), is a eukaryotic protein that mediates the nuclear export of various proteins and RNAs.
The analysis highlights History and Regions as prominent areas in the source structure around XPO1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around XPO1 shows recurring relationship patterns in the source. For example, XPO1 → Cajal body, cytoplasm, cytosol, host cell, intracellular anatomical structure, intracellular membrane-bounded organelle, intracellular protein transport, intracellular transport of virus, kinetochore, lamellae anulatae, membrane, mRNA transport, negative regulation of transcription by RNA polymerase II, nuclear envelope, nuclear export signal receptor activity, nuclear membrane, nucleocytoplasmic transport, nucleolus, nucleoplasm, nucleus Another extracted example is XPO1 → abdominal wall, dermis, embryo, epiblast, epithelium of nasopharynx, genital tubercle, germinal epithelium, Gonadal ridge, human fetus, mandibular prominence, medullary collecting duct, palpebral conjunctiva, parietal pleura, primitive streak, skin of hip, tail of embryo, tibia, trabecular bone, ventricular zone, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp export nuclear chr human band chromosome crm1 protein gene transport location various also mouse ribosomal viral exportin function external
TTTA extracted 122 structured relationships around XPO1. Examples in this analysis include XPO1 → Aliases → XPO1, CRM1, emb, exp1, exportin 1, CRM-1 and XPO1 → Available structures → Available structuresPDBOrtholog search: C9JV99 PDBe C9JV99 RCSB List of PDB id codes1W9C, 2L1L, 3GB8, 4BSM, 4BSN, 5DIS. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| XPO1 | Aliases | XPO1, CRM1, emb, exp1, exportin 1, CRM-1 | 1.00 | infobox |
| XPO1 | Available structures | Available structuresPDBOrtholog search: C9JV99 PDBe C9JV99 RCSB List of PDB id codes1W9C, 2L1L, 3GB8, 4BSM, 4BSN, 5DIS | 1.00 | infobox |
| XPO1 | Band | 2p15 | 1.00 | infobox |
| XPO1 | Band | 11|11 A3.2 | 1.00 | infobox |
| XPO1 | Bgee | tibia | 1.00 | infobox |
| XPO1 | Bgee | ventricular zone | 1.00 | infobox |
| XPO1 | Bgee | germinal epithelium | 1.00 | infobox |
| XPO1 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| XPO1 | Bgee | parietal pleura | 1.00 | infobox |
| XPO1 | Bgee | visceral pleura | 1.00 | infobox |
| XPO1 | Bgee | embryo | 1.00 | infobox |
| XPO1 | Bgee | skin of hip | 1.00 | infobox |
| XPO1 | Bgee | trabecular bone | 1.00 | infobox |
| XPO1 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| XPO1 | Bgee | tail of embryo | 1.00 | infobox |
| XPO1 | Bgee | primitive streak | 1.00 | infobox |
| XPO1 | Bgee | genital tubercle | 1.00 | infobox |
| XPO1 | Bgee | Gonadal ridge | 1.00 | infobox |
| XPO1 | Bgee | dermis | 1.00 | infobox |
| XPO1 | Bgee | abdominal wall | 1.00 | infobox |
| XPO1 | Bgee | epiblast | 1.00 | infobox |
| XPO1 | Bgee | human fetus | 1.00 | infobox |
| XPO1 | Bgee | mandibular prominence | 1.00 | infobox |
| XPO1 | Bgee | medullary collecting duct | 1.00 | infobox |
| XPO1 | BioGPS | More reference expression data | 1.00 | infobox |
| XPO1 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| XPO1 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| XPO1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| XPO1 | End | 61,538,741 bp | 1.00 | infobox |
| XPO1 | End | 23,248,249 bp | 1.00 | infobox |
The concept neighborhoods around XPO1 bring nearby vocabulary together. In this analysis, examples include Export, Involved and Ribosomal. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For XPO1, one of the stronger structural bridges in this analysis connects XPO1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around XPO1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — XPO1 · EN edition · Analysis: TopicsToTalkAbout
