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Complement receptor 1

Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene.

Regions, Gene structure and isoforms & Role in blood groups

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Aliases
CR1, C3BR, C4BR, CD35, KN, complement component 3b/4b receptor 1 (Knops blood group), complement C3b/C4b receptor 1 (Knops blood group)
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1GKG, 1GKN, 1PPQ, 2Q7Z, 2MCY, 2MCZ, 5FO9
Band
1q32.2
Bgee
blood · monocyte · spleen · appendix · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 1 (human)

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Overview

Gene region

Gene structure and isoforms

Structure

Alleles

Rosetting

Role in blood groups

Clinical diagnostic

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Map overview Semantic statistics

Complement receptor 1

Nodes87
Edges86
Triples83
Avg. degree1.98
Density0.022989
Components1

How this topic connects Entity context

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Complement receptor 1

Top relations

Gene ontology · 26
Complement receptor 1 → cell surface, complement activation, classical pathway, complement component C3b binding, complement component C3b receptor activity, complement component C4b binding, complement component C4b receptor activity, complement receptor mediated signaling pathway, extracellular exosome, ficolin-1-rich granule membrane, immune system process, innate immune response, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of complement activation, alternative pathway, negative regulation of complement activation, classical pathway, negative regulation of serine-type endopeptidase activity, neutrophil degranulation, plasma membrane, positive regulation of serine-type endopeptidase activity
related to Alleles · 17
Complement receptor 1 → African, C3b, C4b, CR1, CR1-like, Curiously, European, Four, GPI, Homozygotes, LHR-A, LHR-B, LHR-C, Multiple, The, These, Two
Bgee · 10
Complement receptor 1 → appendix, blood, bone marrow, bone marrow cell, granulocyte, lymph node, monocyte, spleen, superficial temporal artery, trabecular bone
RNA expression pattern · 10
Complement receptor 1 → appendix, blood, bone marrow, bone marrow cell, granulocyte, lymph node, monocyte, spleen, superficial temporal artery, trabecular bone
Aliases · 1
Complement receptor 1 → CR1, C3BR, C4BR, CD35, KN, complement component 3b/4b receptor 1 (Knops blood group), complement C3b/C4b receptor 1 (Knops blood group)
Available structures · 1
Complement receptor 1 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1GKG, 1GKN, 1PPQ, 2Q7Z, 2MCY, 2MCZ, 5FO9
Band · 1
Complement receptor 1 → 1q32.2
BioGPS · 1
Complement receptor 1 → More reference expression data
Chr. · 1
Complement receptor 1 → Chromosome 1 (human)
Databases · 1
Complement receptor 1 → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

gene cr1 protein complement receptor erythrocytes blood human also alleles cr2 immune region system c3b c4b complexes exons membrane knops

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Complement receptor 1AliasesCR1, C3BR, C4BR, CD35, KN, complement component 3b/4b receptor 1 (Knops blood group), complement C3b/C4b receptor 1 (Knops blood group)1.00infobox
Complement receptor 1Available structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1GKG, 1GKN, 1PPQ, 2Q7Z, 2MCY, 2MCZ, 5FO91.00infobox
Complement receptor 1Band1q32.21.00infobox
Complement receptor 1Bgeeblood1.00infobox
Complement receptor 1Bgeemonocyte1.00infobox
Complement receptor 1Bgeespleen1.00infobox
Complement receptor 1Bgeeappendix1.00infobox
Complement receptor 1Bgeelymph node1.00infobox
Complement receptor 1Bgeebone marrow1.00infobox
Complement receptor 1Bgeetrabecular bone1.00infobox
Complement receptor 1Bgeegranulocyte1.00infobox
Complement receptor 1Bgeesuperficial temporal artery1.00infobox
Complement receptor 1Bgeebone marrow cell1.00infobox
Complement receptor 1BioGPSMore reference expression data1.00infobox
Complement receptor 1Chr.Chromosome 1 (human)1.00infobox
Complement receptor 1DatabasesNCBI: entry; OMA: entry1.00infobox
Complement receptor 1End207,641,765 bp1.00infobox
Complement receptor 1EnsemblENSG000002037101.00infobox
Complement receptor 1Entrez13781.00infobox
Complement receptor 1External IDsOMIM: 120620; GeneCards: CR11.00infobox
Complement receptor 1Gene location (Human)Gene location (Human)Chr.Chromosome 1 (human)Band1q32.2Start207,496,147 bpEnd207,641,765 bp1.00infobox
Complement receptor 1Gene ontologyvirus receptor activity1.00infobox
Complement receptor 1Gene ontologycomplement component C3b receptor activity1.00infobox
Complement receptor 1Gene ontologycomplement component C4b receptor activity1.00infobox
Complement receptor 1Gene ontologycomplement component C3b binding1.00infobox
Complement receptor 1Gene ontologycomplement component C4b binding1.00infobox
Complement receptor 1Gene ontologyintegral component of membrane1.00infobox
Complement receptor 1Gene ontologymembrane1.00infobox
Complement receptor 1Gene ontologyplasma membrane1.00infobox
Complement receptor 1Gene ontologyintegral component of plasma membrane1.00infobox

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