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Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the complement system of vertebrate animals and contributes to innate immunity. In humans, it is encoded on chromosome 19 by a gene called C3.
The analysis highlights Measurement, Function and Clinical significance as prominent areas in the source structure around Complement component 3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Complement component 3 shows recurring relationship patterns in the source. For example, Complement component 3 → blood microparticle, C5L2 anaphylatoxin chemotactic receptor binding, complement activation, complement activation, alternative pathway, complement activation, classical pathway, endopeptidase inhibitor activity, extracellular exosome, extracellular fluid, extracellular region, fatty acid metabolic process, G protein-coupled receptor signaling pathway, immune response, immune system process, inflammatory response, innate immune response, lipid metabolism, negative regulation of endopeptidase activity, plasma membrane, positive regulation of activation of membrane attack complex, positive regulation of angiogenesis Another extracted example is Complement component 3 → gallbladder, gastric mucosa, germinal epithelium, granulocyte, intercostal muscle, left adrenal cortex, left lobe of liver, left uterine tube, mesenteric lymph nodes, palpebral conjunctiva, parietal pleura, pericardium, peritoneum, right adrenal cortex, right lobe of liver, right lung, subcutaneous adipose tissue, superior surface of tongue, tunica adventitia of aorta, white adipose tissue. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
c3 complement c3b factor bp system human chromosome 19 chr band deficiency component protein gene c3a activation activated pathway alternative
TTTA extracted 120 structured relationships around Complement component 3. Examples in this analysis include Complement component 3 → Aliases → C3, AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement component 3, complement C3 and Complement component 3 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ONT, 1C3D, 1GHQ, 1W2S, 2A73, 2A74, 2GOX, 2I07, 2ICE, 2ICF, 2NOJ, 2QKI, 2WII, 2WIN, 2WY7, 2WY8, 2XQW, 2XWB,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Complement component 3 | Aliases | C3, AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement component 3, complement C3 | 1.00 | infobox |
| Complement component 3 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4ONT, 1C3D, 1GHQ, 1W2S, 2A73, 2A74, 2GOX, 2I07, 2ICE, 2ICF, 2NOJ, 2QKI, 2WII, 2WIN, 2WY7, 2WY8, 2XQW, 2XWB,… | 1.00 | infobox |
| Complement component 3 | Band | 19p13.3 | 1.00 | infobox |
| Complement component 3 | Band | 17 D|17 29.72 cM | 1.00 | infobox |
| Complement component 3 | Bgee | parietal pleura | 1.00 | infobox |
| Complement component 3 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| Complement component 3 | Bgee | right lobe of liver | 1.00 | infobox |
| Complement component 3 | Bgee | germinal epithelium | 1.00 | infobox |
| Complement component 3 | Bgee | pericardium | 1.00 | infobox |
| Complement component 3 | Bgee | peritoneum | 1.00 | infobox |
| Complement component 3 | Bgee | gastric mucosa | 1.00 | infobox |
| Complement component 3 | Bgee | left uterine tube | 1.00 | infobox |
| Complement component 3 | Bgee | right adrenal cortex | 1.00 | infobox |
| Complement component 3 | Bgee | left adrenal cortex | 1.00 | infobox |
| Complement component 3 | Bgee | left lobe of liver | 1.00 | infobox |
| Complement component 3 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| Complement component 3 | Bgee | gallbladder | 1.00 | infobox |
| Complement component 3 | Bgee | intercostal muscle | 1.00 | infobox |
| Complement component 3 | Bgee | tunica adventitia of aorta | 1.00 | infobox |
| Complement component 3 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| Complement component 3 | Bgee | superior surface of tongue | 1.00 | infobox |
| Complement component 3 | Bgee | white adipose tissue | 1.00 | infobox |
| Complement component 3 | Bgee | granulocyte | 1.00 | infobox |
| Complement component 3 | Bgee | right lung | 1.00 | infobox |
| Complement component 3 | BioGPS | n/a | 1.00 | infobox |
| Complement component 3 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| Complement component 3 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| Complement component 3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Complement component 3 | End | 6,730,562 bp | 1.00 | infobox |
| Complement component 3 | End | 57,535,136 bp | 1.00 | infobox |
The concept neighborhoods around Complement component 3 bring nearby vocabulary together. In this analysis, examples include System, Component and Alternative. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Complement component 3, one of the stronger structural bridges in this analysis connects Complement component 3 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Complement component 3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Complement component 3 · EN edition · Analysis: TopicsToTalkAbout