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Collagenase: Applications, The MEROPS M9 family & Therapeutic uses

Collagenases are enzymes that break the peptide bonds in collagen. They assist in destroying extracellular structures in the pathogenesis of bacteria such as Clostridium. They are considered a virulence factor, facilitating the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.

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Collagenase topic overview

The analysis highlights Applications, The MEROPS M9 family and Therapeutic uses as prominent areas in the source structure around Collagenase.

Related topics
51
Source areas
4
Connected nodes
55
Extracted relationships
42
Concept neighborhoods
24
Bridge connections
55

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

The MEROPS M9 family · 32 topics
Overview · 11 topics
Therapeutic uses · 5 topics
Other uses · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
EC number
3.4.24.7
HGNC
7155
Locus
Chr. 11 q21-q22
NCBI gene
4312
OMIM
120353

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Therapeutic uses

The MEROPS M9 family

Other uses

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Collagenase connects Entity context

The extracted context around Collagenase shows recurring relationship patterns in the source. For example, Collagenase → Clostridium, Collagen, Gly, Got, HEXXH, M9, M9A, M9B, MA, MEROPS, Microbial, The, This, Vibrio, Xaa, Yaa Another extracted example is Collagenase → Collagenases, Dupuytren's, Peyronie's, Qwo, Santyl, Xiaflex. Use these groups to spot repeated connection types before inspecting the individual relationships.

Collagenase

Top relations

related to The MEROPS M9 family · 16
Collagenase → Clostridium, Collagen, Gly, Got, HEXXH, M9, M9A, M9B, MA, MEROPS, Microbial, The, This, Vibrio, Xaa, Yaa
related to Therapeutic uses · 6
Collagenase → Collagenases, Dupuytren's, Peyronie's, Qwo, Santyl, Xiaflex
related to External links · 4
Collagenase → Collagenases, Medicine Medical Subject Headings, MeSH, National Library
Domains · 1
Collagenase → InterPro
EC number · 1
Collagenase → 3.4.24.7
HGNC · 1
Collagenase → 7155
Locus · 1
Collagenase → Chr. 11 q21-q22
NCBI gene · 1
Collagenase → 4312
OMIM · 1
Collagenase → 120353
RefSeq · 1
Collagenase → NM_002421

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

collagenases bacteria collagen tissue structures clostridium motif metalloproteases used gas gangrene part extracellular cells body made cell vibrio sequence family

Collagenase relationships Subject–Predicate–Object triples

TTTA extracted 42 structured relationships around Collagenase. Examples in this analysis include Collagenase → Domains → InterPro and Collagenase → EC number → 3.4.24.7. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CollagenaseDomainsInterPro1.00infobox
CollagenaseEC number3.4.24.71.00infobox
CollagenaseHGNC71551.00infobox
CollagenaseLocusChr. 11 q21-q221.00infobox
CollagenaseNCBI gene43121.00infobox
CollagenaseOMIM1203531.00infobox
CollagenaseRefSeqNM_0024211.00infobox
CollagenaseSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CollagenaseStructuresSwiss-model1.00infobox
CollagenaseSymbolMMP11.00infobox
CollagenaseUniProtP039561.00infobox
Clostridiuminstance ofThey assist in destroying extracellular structures in the pathogenesis of bacteria0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Collagenase bring nearby vocabulary together. In this analysis, examples include Made, Sequence and Used. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • bacteria
    • Vibrio
    • Clostridium
    • Produced
    • Collagenases
    • Body
    • Bonds
    • Citation
    • Cleavage
    • Extracellular
    • Gene
    • Made
    • Microbial
  • Collagenase
    • Made
    • Sequence
    • Used
    • Extracellular
    • M9
    • Matrix
    • Merops
    • Microbial
    • Produced
    • Q21-q22
    • Uses
    • Family
  • collagenase
    • Made
    • Sequence
    • Used
    • Extracellular
    • M9
    • Matrix
    • Merops
    • Microbial
    • Produced
    • Q21-q22
    • Uses
    • Family
  • collagen
    • Cleavage
    • Collagenases
    • Collagenase
    • Cell
    • Citation
    • Enzymes
    • Extracellular
    • Gene
    • Made
    • Matrix
    • Needed
    • Produced
  • clostridium
    • Vibrio
    • Collagenases
    • Citation
    • Cleavage
    • Extracellular
    • Gene
    • Microbial
    • Needed
    • Produced
    • Gangrene
    • Gas
    • Sequence
  • cleavage
    • Collagen
    • Cell
    • Citation
    • Extracellular
    • Gene
    • Made
    • Matrix
    • Needed
    • Produced
    • Sequence
    • Vibrio
    • Clostridium
  • vibrio
    • Bacteria
    • Clostridium
    • Collagenases
    • Bonds
    • Citation
    • Cleavage
    • Gene
    • Microbial
    • Needed
    • Produced
    • Sequence
    • Tissue
  • therapeutic uses
    • M9
    • Merops
    • Family
    • Cells
    • Chr
    • Citation
    • Gene
    • Microbial
    • Needed
    • Q21-q22
    • Structures
    • Tissue

Connections between topic areas Semantic bridges

For Collagenase, one of the stronger structural bridges in this analysis connects Collagenase with The MEROPS M9 family. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CollagenaseThe MEROPS M9 family · splits 23 ⟂ 33
CollagenaseOverview · splits 44 ⟂ 12
CollagenaseTherapeutic uses · splits 50 ⟂ 6
CollagenaseOther uses · splits 52 ⟂ 4

Map overview Semantic statistics

Collagenase

Nodes56
Edges55
Triples42
Avg. degree1.96
Density0.035714
Components1

Source & methodology

TTTA analyzes the structure around Collagenase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, The MEROPS M9 family & Therapeutic uses, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Collagenase · EN edition · Analysis: TopicsToTalkAbout

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