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Papain

Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme present in papaya (Carica papaya) and mountain papaya (Vasconcellea cundinamarcensis). It is the namesake member of the papain-like protease family.

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Applications & Products

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Explore the main themes, entities and connections around Papain. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

14 related topics

Uses

13 related topics

Human cysteine proteases from papain family

12 related topics

Immunoglobulins

11 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR000668 · PF00112
Available protein structures:
IPR000668 · PF00112
InterPro
IPR000668
PDB
IPR000668 PF00112 (ECOD; PDBsum)
Pfam
PF00112
PROSITE
PDOC00126

Topics to explore

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Overview

Papain family

Structure

Function

Uses

Immunoglobulins

Production

US restriction on marketing

Human cysteine proteases from papain family

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Papain

Nodes86
Edges85
Triples93
Avg. degree1.98
Density0.023256
Components1

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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Papain

Top relations

related to External links · 17
Papain → Applications, Archived, BIOZYMPapain, C01, Inhibitors, Medicine Medical Subject Headings, MeSH, National Library, Overview, P00784, PDB, PDBe-KB, Proteopedia, SubstratesData, The MEROPS, UniProt, Wayback MachinePapain
related to Unapproved topical papain products · 15
Papain → Accuzyme, Allanfil, Allanzyme, Ethezyme, FDA, Gladase, In, Kovia, Other, Panafil, Pap Urea, Reports, Topical, Trade, Ziox
related to US restriction on marketing · 14
Papain → According, Center, Drug Administration, Drug Evaluation, FDA, FDA's, Janet Woodcock, November, On September, Papain-containing, Research, The FDA, These, US Food
related to Function · 8
Papain → Asn-175, Cys-25, Fab, Fc, His-159, In, The, This
related to Immunoglobulins · 7
Papain → An, CroFab, Crotalid, Digibind, Fab, Fc, The
related to Uses · 7
Papain → After, European, Left, Meat, Pasteur, South America, The
related to Papain family · 6
Papain → Amino, Among, Members, N-terminal, Papain-like, The
related to Structure · 4
Papain → Aspartate-158, Its, The, This
related to Production · 3
Papain → It, The, This
AlphaFold · 2
Papain → IPR000668, PF00112

Important terminology Word statistics

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Important terminology

used drug products topical enzyme protease papaya also cysteine peptide known active family propeptide latex amino catalytic use tissue food

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
PapainAlphaFoldIPR0006681.00infobox
PapainAlphaFoldPF001121.00infobox
PapainAvailable protein structures:IPR0006681.00infobox
PapainAvailable protein structures:PF001121.00infobox
PapainInterProIPR0006681.00infobox
PapainPDBIPR000668 PF00112 (ECOD; PDBsum)1.00infobox
PapainPfamPF001121.00infobox
PapainPROSITEPDOC001261.00infobox
PapainSCOP21aec / SCOPe / SUPFAM1.00infobox
PapainSymbolPeptidase_C11.00infobox
Papainis arelatively heat-resistant enzyme0.90text
Papainis amain ingredient of Papacarie0.90text

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