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Comparative genomic hybridization

Comparative genomic hybridization (CGH) is a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level in the DNA of a test sample compared to a reference sample, without the need for culturing cells. The aim of this technique is to quickly and efficiently compare two genomic DNA samples arising from two sources…

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Array comparative genomic hybridization

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Limitations of CGH and array CGH

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Comparative genomic hybridization

Nodes102
Edges101
Triples20
Avg. degree1.98
Density0.019608
Components1

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Comparative genomic hybridization

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related to Array comparative genomic hybridization · 7
Comparative genomic hybridization → Array, Array CGH, CGH, DNA, In, This, With

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cgh dna array chromosomal cancer abnormalities used using resolution reference test aberrations chromosomes may technique genome hybridization also two genomic

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
reciprocal translocationsinstance ofThis is because balanced chromosomal abnormalities0.80text
inversions or ring chromosomes do not affect copy numberinstance ofThis is because balanced chromosomal abnormalities0.80text
which is what is detected by CGH technologiesinstance ofThis is because balanced chromosomal abnormalities0.80text
microdissectioninstance ofAs new techniques0.80text
degenerate oligonucleotide primed polymerase chain reactioninstance ofAs new techniques0.80text
cDNAinstance ofNow probes of various origins0.80text
genomic PCR productsinstance ofNow probes of various origins0.80text
bacterial artificial chromosomesinstance ofNow probes of various origins0.80text
cancerinstance ofThis method allows one to identify new recurrent chromosome changes such as microdeletions and duplications in human conditions0.80text
birth defects due to chromosome aberrations.MethodologyArray CGH is based on the same principle as conventional CGHinstance ofThis method allows one to identify new recurrent chromosome changes such as microdeletions and duplications in human conditions0.80text
Down syndromeinstance ofmiscarriage or conditions0.80text
balanced reciprocal translocations or Robertsonian translocationsinstance ofIt may also be used in couples carrying chromosomal translocations0.80text

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