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Chlorphenamine

Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever). It is taken orally (by mouth). The medication takes effect within two hours and lasts for about 4–6 hours. It is a first-generation antihistamine and works by blocking the histamine H1…

Applications, Chemistry & Pharmacology

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
R06AB04 (WHO)
Bioavailability
25 to 50%
CAS Number
132-22-9 Y
ChEBI
CHEBI:52010 Y

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Overview

Medical uses

Side effects

Pharmacology

Chemistry

Naming

  • INN International Nonproprietary Name
  • USAN United States Adopted Name
  • BAN British Approved Name

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Map overview Semantic statistics

Chlorphenamine

Nodes60
Edges59
Triples67
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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Chlorphenamine

Top relations

related to Names · 12
Chlorphenamine → Allerest, BANTooltip British Approved Name, Brand, Chlor-Trimeton, Chlorphen-12, Demazin, Hour, INNTooltip International Nonproprietary Name, Name, Piriton, Tylenol Cold/Allergy, USANTooltip United States Adopted
related to Combination products · 8
Chlorphenamine → Coricidin, Cêgripe, Elvis Presley, FDA, In, Tutag, Tylenol, Vernate
related to Chemistry · 5
Chlorphenamine → Dimetapp, Drixoral, Naphcon, Polaramine, The
related to Pharmacodynamics · 5
Chlorphenamine → H1, In, It, Kd, The
Legal status · 4
Chlorphenamine → AU: S3 (Pharmacist only), CN: OTC, UK: P (Pharmacy medicines), US: OTC
related to Synthesis · 4
Chlorphenamine → Alkylating, In, N-dimethyl-2-pyridinepropanamine, There
3D model (JSmol) · 1
Chlorphenamine → Interactive image
AHFS/Drugs.com · 1
Chlorphenamine → Monograph
ATC code · 1
Chlorphenamine → R06AB04 (WHO)
Bioavailability · 1
Chlorphenamine → 25 to 50%

Important terminology Word statistics

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Important terminology

antihistamine h1 receptor medication effects include side dexchlorphenamine chlorpheniramine mouth hours names antihistamines affinity muscarinic acetylcholine kd nm also first-generation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Chlorphenamine3D model (JSmol)Interactive image1.00infobox
ChlorphenamineAHFS/Drugs.comMonograph1.00infobox
ChlorphenamineATC codeR06AB04 (WHO)1.00infobox
ChlorphenamineBioavailability25 to 50%1.00infobox
ChlorphenamineCAS Number132-22-9 Y1.00infobox
ChlorphenamineChEBICHEBI:52010 Y1.00infobox
ChlorphenamineChEMBLChEMBL505 Y1.00infobox
ChlorphenamineChemSpider2624 Y1.00infobox
ChlorphenamineCompTox Dashboard (EPA)DTXSID00228041.00infobox
ChlorphenamineDrugBankDB01114 Y1.00infobox
ChlorphenamineECHA InfoCard100.004.5961.00infobox
ChlorphenamineElimination half-life13.9–43.4 hours1.00infobox
ChlorphenamineExcretionKidney1.00infobox
ChlorphenamineFormulaC16H19ClN21.00infobox
ChlorphenamineIUPHAR/BPS12101.00infobox
ChlorphenamineKEGGD07398 Y1.00infobox
ChlorphenamineLegal statusAU: S3 (Pharmacist only)1.00infobox
ChlorphenamineLegal statusUK: P (Pharmacy medicines)1.00infobox
ChlorphenamineLegal statusUS: OTC1.00infobox
ChlorphenamineLegal statusCN: OTC1.00infobox
ChlorphenamineMedlinePlusa6825431.00infobox
ChlorphenamineMetabolismLiver (CYP2D6)1.00infobox
ChlorphenamineMolar mass274.79 g·mol−11.00infobox
ChlorphenaminePregnancy categoryAU: A1.00infobox
ChlorphenamineProtein binding72%1.00infobox
ChlorphenaminePubChem CID27251.00infobox
ChlorphenamineRoutes of administrationOral, intravenous, intramuscular, subcutaneous1.00infobox
ChlorphenamineSolubility in water0.55 g/100 mL, liquid mg/mL (20 °C)1.00infobox
ChlorphenamineTrade namesChlor-Trimeton; Piriton; Chlor-Tripolon; Allergex1.00infobox
ChlorphenamineUNII3U6IO1965U1.00infobox

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