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Chlorphenamine: Applications, Chemistry & Pharmacology

Chlorphenamine (CP, CPM), also known as chlorpheniramine, is an antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis (hay fever). It is taken orally (by mouth). The medication takes effect within two hours and lasts for about 4–6 hours. It is a first-generation antihistamine and works by blocking the histamine H1…

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Chlorphenamine topic overview

The analysis highlights Applications, Chemistry and Pharmacology as prominent areas in the source structure around Chlorphenamine.

Related topics
53
Source areas
6
Connected nodes
59
Extracted relationships
67
Concept neighborhoods
15
Bridge connections
59

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Chemistry · 19 topics
Pharmacology · 13 topics
Overview · 9 topics
Medical uses · 6 topics
Naming · 3 topics
Side effects · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
R06AB04 (WHO)
Bioavailability
25 to 50%
CAS Number
132-22-9 Y
ChEBI
CHEBI:52010 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Pharmacology

Chemistry

Naming

  • INN International Nonproprietary Name
  • USAN United States Adopted Name
  • BAN British Approved Name

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Chlorphenamine connects Entity context

The extracted context around Chlorphenamine shows recurring relationship patterns in the source. For example, Chlorphenamine → Allerest, BANTooltip British Approved Name, Brand, Chlor-Trimeton, Chlorphen-12, Demazin, Hour, INNTooltip International Nonproprietary Name, Name, Piriton, Tylenol Cold/Allergy, USANTooltip United States Adopted Another extracted example is Chlorphenamine → Coricidin, Cêgripe, Elvis Presley, FDA, In, Tutag, Tylenol, Vernate. Use these groups to spot repeated connection types before inspecting the individual relationships.

Chlorphenamine

Top relations

related to Names · 12
Chlorphenamine → Allerest, BANTooltip British Approved Name, Brand, Chlor-Trimeton, Chlorphen-12, Demazin, Hour, INNTooltip International Nonproprietary Name, Name, Piriton, Tylenol Cold/Allergy, USANTooltip United States Adopted
related to Combination products · 8
Chlorphenamine → Coricidin, Cêgripe, Elvis Presley, FDA, In, Tutag, Tylenol, Vernate
related to Chemistry · 5
Chlorphenamine → Dimetapp, Drixoral, Naphcon, Polaramine, The
related to Pharmacodynamics · 5
Chlorphenamine → H1, In, It, Kd, The
Legal status · 4
Chlorphenamine → AU: S3 (Pharmacist only), CN: OTC, UK: P (Pharmacy medicines), US: OTC
related to Synthesis · 4
Chlorphenamine → Alkylating, In, N-dimethyl-2-pyridinepropanamine, There
3D model (JSmol) · 1
Chlorphenamine → Interactive image
AHFS/Drugs.com · 1
Chlorphenamine → Monograph
ATC code · 1
Chlorphenamine → R06AB04 (WHO)
Bioavailability · 1
Chlorphenamine → 25 to 50%

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

antihistamine h1 receptor medication effects include side dexchlorphenamine chlorpheniramine mouth hours names antihistamines affinity muscarinic acetylcholine kd nm also first-generation

Chlorphenamine relationships Subject–Predicate–Object triples

TTTA extracted 67 structured relationships around Chlorphenamine. Examples in this analysis include Chlorphenamine → 3D model (JSmol) → Interactive image and Chlorphenamine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Chlorphenamine3D model (JSmol)Interactive image1.00infobox
ChlorphenamineAHFS/Drugs.comMonograph1.00infobox
ChlorphenamineATC codeR06AB04 (WHO)1.00infobox
ChlorphenamineBioavailability25 to 50%1.00infobox
ChlorphenamineCAS Number132-22-9 Y1.00infobox
ChlorphenamineChEBICHEBI:52010 Y1.00infobox
ChlorphenamineChEMBLChEMBL505 Y1.00infobox
ChlorphenamineChemSpider2624 Y1.00infobox
ChlorphenamineCompTox Dashboard (EPA)DTXSID00228041.00infobox
ChlorphenamineDrugBankDB01114 Y1.00infobox
ChlorphenamineECHA InfoCard100.004.5961.00infobox
ChlorphenamineElimination half-life13.9–43.4 hours1.00infobox
ChlorphenamineExcretionKidney1.00infobox
ChlorphenamineFormulaC16H19ClN21.00infobox
ChlorphenamineIUPHAR/BPS12101.00infobox
ChlorphenamineKEGGD07398 Y1.00infobox
ChlorphenamineLegal statusAU: S3 (Pharmacist only)1.00infobox
ChlorphenamineLegal statusUK: P (Pharmacy medicines)1.00infobox
ChlorphenamineLegal statusUS: OTC1.00infobox
ChlorphenamineLegal statusCN: OTC1.00infobox
ChlorphenamineMedlinePlusa6825431.00infobox
ChlorphenamineMetabolismLiver (CYP2D6)1.00infobox
ChlorphenamineMolar mass274.79 g·mol−11.00infobox
ChlorphenaminePregnancy categoryAU: A1.00infobox
ChlorphenamineProtein binding72%1.00infobox
ChlorphenaminePubChem CID27251.00infobox
ChlorphenamineRoutes of administrationOral, intravenous, intramuscular, subcutaneous1.00infobox
ChlorphenamineSolubility in water0.55 g/100 mL, liquid mg/mL (20 °C)1.00infobox
ChlorphenamineTrade namesChlor-Trimeton; Piriton; Chlor-Tripolon; Allergex1.00infobox
ChlorphenamineUNII3U6IO1965U1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Chlorphenamine bring nearby vocabulary together. In this analysis, examples include Antihistamines, Combined and Antihistamine. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Chlorphenamine
    • Antihistamines
    • Combined
    • Antihistamine
    • Known
    • Amide
    • Anticholinergic
    • Chlorpheniramine
    • Drug
    • First-generation
    • Hours
    • Name
    • Presence
  • chlorphenamine
    • Antihistamines
    • Combined
    • Antihistamine
    • Known
    • Amide
    • Anticholinergic
    • Chlorpheniramine
    • Drug
    • First-generation
    • Hours
    • Name
    • Presence
  • first-generation antihistamine
    • Antihistamines
    • H1
    • Histamine
    • Use
    • Anticholinergic
    • Known
    • Medical
    • Names
    • Study
    • Chlorphenamine
    • Chlorpheniramine
    • Combined
  • antihistamine
    • H1
    • Histamine
    • Known
    • Medical
    • Names
    • Chlorphenamine
    • Chlorpheniramine
    • Combined
    • First-generation
    • Hours
    • Name
    • Side
  • muscarinic acetylcholine receptor
    • Muscarinic
    • Receptors
    • Found
    • Affinity
    • Study
    • Dexchlorphenamine
    • Receptor
    • Commonly
    • Also
    • Anticholinergic
    • Drug
    • Kd
  • side effects
    • Effects
    • Side
    • Include
    • Dry
    • Restlessness
    • Mouth
    • Medical
    • Names
    • Combined
    • Hours
    • Name
    • Antihistamine
  • histamine h1 receptor
    • Receptor
    • Found
    • Nm
    • Histamine
    • Study
    • Dexchlorphenamine
    • Kd
    • Receptors
    • Acetylcholine
    • Muscarinic
  • anticholinergic
    • Commonly
    • Use
    • Drug
    • First-generation
    • Receptors
    • Study
    • Acetylcholine
    • Antihistamines
    • Muscarinic
    • Chlorphenamine

Connections between topic areas Semantic bridges

For Chlorphenamine, one of the stronger structural bridges in this analysis connects Chlorphenamine with Chemistry. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Chlorphenamine — Chemistry · splits 40 ⟂ 20
Chlorphenamine — Pharmacology · splits 46 ⟂ 14
Chlorphenamine — Overview · splits 50 ⟂ 10
Chlorphenamine — Medical uses · splits 53 ⟂ 7
Chlorphenamine — Side effects · splits 56 ⟂ 4
Chlorphenamine — Naming · splits 56 ⟂ 4

Map overview Semantic statistics

Chlorphenamine

Nodes60
Edges59
Triples67
Avg. degree1.97
Density0.033333
Components1

Source & methodology

TTTA analyzes the structure around Chlorphenamine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Chemistry & Pharmacology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Chlorphenamine · EN edition · Analysis: TopicsToTalkAbout

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