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T-cadherin

T-cadherin, also known as cadherin 13, H-cadherin (heart), and CDH13, is a unique member of the cadherin protein family. Unlike typical cadherins that span across the cell membrane with distinct transmembrane and cytoplasmic domains, T-cadherin lacks these features and is instead anchored to the cell's plasma membrane through a GPI anchor.

Art, Regulation of cell growth & Functions in the vasculature

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Regulation of cell growth

AstrocytesPlatelet-derived growth factorEpidermal growth factorInsulin-like growth factorP21
40 related topics

Functions in the vasculature

Spinal cordSpleenAtheroscleroticAngioplastyStenosis
18 related topics

Mediation of intracellular signaling in vascular cells

IntestinalTransfectedVE-cadherinConfocal microscopyLipid rafts
15 related topics

Guiding molecules in vascular and nervous systems

Somitic sclerotomeNeural crest cellsNeurite
3 related topics

Key facts & relationships

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Aliases
CDH13, CDHH, P105, cadherin 13
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2V37
Band
16q23.3 · 8 E1|8 65.97 cM
Bgee
Descending thoracic aorta · right coronary artery · ascending aorta · stromal cell of endometrium · popliteal artery
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

Topics to explore

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Overview

Mediation of intracellular signaling in vascular cells

Functions in the vasculature

Regulation of cell growth

Guiding molecules in vascular and nervous systems

Advanced semantic analysis

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Map overview Semantic statistics

T-cadherin

Nodes89
Edges88
Triples152
Avg. degree1.98
Density0.022472
Components1

How this topic connects Entity context

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T-cadherin

Top relations

Gene ontology · 55
T-cadherin → adherens junction organization, adiponectin binding, anchored component of membrane, cadherin binding, calcium ion binding, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, catenin complex, caveola, cell adhesion, cell morphogenesis, cell surface, cell-cell adhesion, cell-cell adhesion mediated by cadherin, cell-cell junction assembly, collagen-containing extracellular matrix, cytoplasm, cytoskeletal protein binding, endothelial cell migration, external side of plasma membrane, extracellular exosome
Bgee · 20
T-cadherin → Achilles tendon, ankle, ankle joint, ascending aorta, cardiac muscle tissue of left ventricle, Descending thoracic aorta, interventricular septum, left coronary artery, muscle of thigh, myocardium of ventricle, popliteal artery, quadriceps femoris muscle, right coronary artery, right ventricle, stromal cell of endometrium, suprachiasmatic nucleus, tibial arteries, tunica media of zone of aorta, vastus lateralis muscle, ventromedial nucleus
RNA expression pattern · 20
T-cadherin → Achilles tendon, ankle, ankle joint, ascending aorta, cardiac muscle tissue of left ventricle, Descending thoracic aorta, interventricular septum, left coronary artery, muscle of thigh, myocardium of ventricle, popliteal artery, quadriceps femoris muscle, right coronary artery, right ventricle, stromal cell of endometrium, suprachiasmatic nucleus, tibial arteries, tunica media of zone of aorta, vastus lateralis muscle, ventromedial nucleus
related to Regulation of cell growth · 14
T-cadherin → BB, C6, EGF, Expression, G2, IGF, In, In T-cadherin, Known, PDGF, Seeding T-cadherin, VSMC, VSMCs, WAF1
related to Mediation of intracellular signaling in vascular cells · 7
T-cadherin → In, MDCS, N-cadherin, The, These, Though T-cadherin, VE-cadherin
related to External links · 5
T-cadherin → CDH13, Medicine Medical Subject Headings, MeSH, National Library, UCSC Genome Browser
related to Functions in the vasculature · 4
T-cadherin → ECs, Expression, The, VSMC
related to Guiding molecules in vascular and nervous systems · 3
T-cadherin → As, Considering, The
Band · 2
T-cadherin → 16q23.3, 8 E1|8 65.97 cM
Chr. · 2
T-cadherin → Chromosome 16 (human), Chromosome 8 (mouse)

Important terminology Word statistics

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Important terminology

cell expression cells human vascular growth tumor signaling bp gene cdh13 associated tissue chr band membrane adiponectin migration metastasis regulation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
T-cadherinAliasesCDH13, CDHH, P105, cadherin 131.00infobox
T-cadherinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2V371.00infobox
T-cadherinBand16q23.31.00infobox
T-cadherinBand8 E1|8 65.97 cM1.00infobox
T-cadherinBgeeDescending thoracic aorta1.00infobox
T-cadherinBgeeright coronary artery1.00infobox
T-cadherinBgeeascending aorta1.00infobox
T-cadherinBgeestromal cell of endometrium1.00infobox
T-cadherinBgeepopliteal artery1.00infobox
T-cadherinBgeetibial arteries1.00infobox
T-cadherinBgeeAchilles tendon1.00infobox
T-cadherinBgeequadriceps femoris muscle1.00infobox
T-cadherinBgeevastus lateralis muscle1.00infobox
T-cadherinBgeeleft coronary artery1.00infobox
T-cadherinBgeeankle1.00infobox
T-cadherinBgeetunica media of zone of aorta1.00infobox
T-cadherinBgeeright ventricle1.00infobox
T-cadherinBgeemyocardium of ventricle1.00infobox
T-cadherinBgeemuscle of thigh1.00infobox
T-cadherinBgeeventromedial nucleus1.00infobox
T-cadherinBgeeinterventricular septum1.00infobox
T-cadherinBgeecardiac muscle tissue of left ventricle1.00infobox
T-cadherinBgeeankle joint1.00infobox
T-cadherinBgeesuprachiasmatic nucleus1.00infobox
T-cadherinBioGPSMore reference expression data1.00infobox
T-cadherinChr.Chromosome 16 (human)1.00infobox
T-cadherinChr.Chromosome 8 (mouse)1.00infobox
T-cadherinDatabasesNCBI: entry; OMA: entry1.00infobox
T-cadherinEnd83,800,640 bp1.00infobox
T-cadherinEnd120,051,660 bp1.00infobox

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