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C1 complex

The C1 complex (complement component 1, C1) is a protein complex involved in the complement system. It is the first component of the classical complement pathway and is composed of the subcomponents C1q, C1r and C1s.

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Function

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Map overview Semantic statistics

C1 complex

Nodes24
Edges23
Triples29
Avg. degree1.92
Density0.083333
Components1

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C1 complex

Top relations

related to Function · 22
C1 complex → Activation, Active C1r, Active C1s, C-reactive, C1, C1q, C1r, C1s, C2, C2a, C2b, C3, C3-convertase, C4, C4a, C4b, C4bC2b, IgG, IgM, Such
related to Structure · 5
C1 complex → C1q, C1qr2s2, C1r, C1s, The C1

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Important terminology

c1q complement c1r c1s c1 complex pathway molecules classical component protein system composed molecule activation binding active involved first subcomponents

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
C-reactive protein or directly to the surface of pathogens.Such binding of C1q leads to conformational changes in the C1q moleculeinstance offor example by binding to pentraxins0.80text
which activates the associated C1r moleculesinstance offor example by binding to pentraxins0.80text
C1 complexrelated to FunctionActivation0.60section
C1 complexrelated to FunctionC10.60section
C1 complexrelated to FunctionThis0.60section
C1 complexrelated to FunctionC1q0.60section
C1 complexrelated to FunctionThe0.60section
C1 complexrelated to FunctionIgM0.60section
C1 complexrelated to FunctionIgG0.60section
C1 complexrelated to FunctionC-reactive0.60section
C1 complexrelated to FunctionSuch0.60section
C1 complexrelated to FunctionC1r0.60section

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