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Complement component 1s: Art & Overview

Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system. C1s is part of the C1 complex. In humans, it is encoded by the C1S gene.

Language: English [EN]
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Complement component 1s topic overview

The analysis highlights Art and Overview as prominent areas in the source structure around Complement component 1s.

Related topics
10
Source areas
1
Connected nodes
11
Extracted relationships
84
Concept neighborhoods
11
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 10 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.4.21.42
Aliases
C1S, EDSPD2, complement C1s
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ELV, 1NZI, 4J1Y, 4LMF, 4LOR, 4LOS, 4LOT
Band
12p13.31 · 6|6 F2
Bgee
pericardium · right lobe of liver · parietal pleura · right ovary · gallbladder
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Complement component 1s connects Entity context

The extracted context around Complement component 1s shows recurring relationship patterns in the source. For example, Complement component 1s → adrenal gland, bone marrow, embryo, gallbladder, gastric mucosa, islet of Langerhans, left ovary, left uterine tube, lens, morula, muscle of thigh, ovary, parietal pleura, pericardium, right lobe of liver, right ovary, synovial joint, tibial nerve, urinary bladder, white adipose tissue Another extracted example is Complement component 1s → blood microparticle, calcium ion binding, complement activation, complement activation, classical pathway, complement activation, lectin pathway, extracellular exosome, extracellular region, extracellular space, hydrolase activity, identical protein binding, immune system process, innate immune response, metal ion binding, peptidase activity, protein binding, proteolysis, regulation of complement activation, serine-type endopeptidase activity, serine-type peptidase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

Complement component 1s

Top relations

Bgee · 20
Complement component 1s → adrenal gland, bone marrow, embryo, gallbladder, gastric mucosa, islet of Langerhans, left ovary, left uterine tube, lens, morula, muscle of thigh, ovary, parietal pleura, pericardium, right lobe of liver, right ovary, synovial joint, tibial nerve, urinary bladder, white adipose tissue
RNA expression pattern · 20
Complement component 1s → adrenal gland, bone marrow, embryo, gallbladder, gastric mucosa, islet of Langerhans, left ovary, left uterine tube, lens, morula, muscle of thigh, ovary, parietal pleura, pericardium, right lobe of liver, right ovary, synovial joint, tibial nerve, urinary bladder, white adipose tissue
Gene ontology · 19
Complement component 1s → blood microparticle, calcium ion binding, complement activation, complement activation, classical pathway, complement activation, lectin pathway, extracellular exosome, extracellular region, extracellular space, hydrolase activity, identical protein binding, immune system process, innate immune response, metal ion binding, peptidase activity, protein binding, proteolysis, regulation of complement activation, serine-type endopeptidase activity, serine-type peptidase activity
Band · 2
Complement component 1s → 12p13.31, 6|6 F2
Chr. · 2
Complement component 1s → Chromosome 12 (human), Chromosome 6 (mouse)
End · 2
Complement component 1s → 124,613,044 bp, 7,071,032 bp
3.4.21.42 · 1
Complement component 1s → ↗
Aliases · 1
Complement component 1s → C1S, EDSPD2, complement C1s
Available structures · 1
Complement component 1s → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ELV, 1NZI, 4J1Y, 4LMF, 4LOR, 4LOS, 4LOT
BioGPS · 1
Complement component 1s → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

c1s bp human gene chr band complement chromosome 12 location c1 protein pathway classical mouse component 21 42 system external

Complement component 1s relationships Subject–Predicate–Object triples

TTTA extracted 84 structured relationships around Complement component 1s. Examples in this analysis include Complement component 1s → 3.4.21.42 → ↗ and Complement component 1s → Aliases → C1S, EDSPD2, complement C1s. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Complement component 1s3.4.21.421.00infobox
Complement component 1sAliasesC1S, EDSPD2, complement C1s1.00infobox
Complement component 1sAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ELV, 1NZI, 4J1Y, 4LMF, 4LOR, 4LOS, 4LOT1.00infobox
Complement component 1sBand12p13.311.00infobox
Complement component 1sBand6|6 F21.00infobox
Complement component 1sBgeepericardium1.00infobox
Complement component 1sBgeeright lobe of liver1.00infobox
Complement component 1sBgeeparietal pleura1.00infobox
Complement component 1sBgeeright ovary1.00infobox
Complement component 1sBgeegallbladder1.00infobox
Complement component 1sBgeeleft ovary1.00infobox
Complement component 1sBgeegastric mucosa1.00infobox
Complement component 1sBgeetibial nerve1.00infobox
Complement component 1sBgeeleft uterine tube1.00infobox
Complement component 1sBgeesynovial joint1.00infobox
Complement component 1sBgeemuscle of thigh1.00infobox
Complement component 1sBgeemorula1.00infobox
Complement component 1sBgeeembryo1.00infobox
Complement component 1sBgeewhite adipose tissue1.00infobox
Complement component 1sBgeebone marrow1.00infobox
Complement component 1sBgeeadrenal gland1.00infobox
Complement component 1sBgeeurinary bladder1.00infobox
Complement component 1sBgeeovary1.00infobox
Complement component 1sBgeelens1.00infobox
Complement component 1sBgeeislet of Langerhans1.00infobox
Complement component 1sBioGPSMore reference expression data1.00infobox
Complement component 1sChr.Chromosome 12 (human)1.00infobox
Complement component 1sChr.Chromosome 6 (mouse)1.00infobox
Complement component 1sDatabasesNCBI: entry; OMA: entry1.00infobox
Complement component 1sEnd7,071,032 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Complement component 1s bring nearby vocabulary together. In this analysis, examples include Activity, Component and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Complement component 1s
    • Activity
    • Component
    • Protein
    • Search
    • System
    • C1
    • C1s
    • Chromosome
    • Location
    • 1r
    • 1s
    • Activated
  • complement component 1s
    • 1r
    • Activated
    • Ec3
    • Esterase
    • Overbar
    • Protein
    • System
    • Activity
    • Component
    • Search
    • C1
    • Lectin
  • c1 esterase
    • Overbar
    • Complex
    • Component
    • Part
    • Protein
    • System
    • Complement
    • C1s
    • 1r
    • Activated
    • Ec3
    • Esterase
  • complement system
    • Activity
    • Component
    • Protein
    • Search
    • System
    • C1
    • C1s
    • Chromosome
    • Location
    • 1r
    • 1s
    • Activated
  • c1 complex
    • Part
    • Complex
    • Component
    • Protein
    • System
    • Complement
    • Lectin
    • C1s
    • 1r
    • Activated
    • Activity
    • Classical
  • classical
    • Pathway
    • Lectin
    • Activity
    • Complex
    • Component
    • End
    • Mouse
    • Part
    • Protein
    • Search
    • System
    • Ucsc
  • protein
    • System
    • Lectin
    • Activity
    • Classical
    • Complex
    • End
    • Mouse
    • Part
    • Pathway
    • Search
    • Ucsc
    • Band
  • gene
    • Location
    • Human
    • End
    • Mouse
    • Search
    • Ucsc
    • Band
    • Lectin
    • Part
    • Pathway
    • Protein
    • System

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Complement component 1s map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Complement component 1s

Nodes12
Edges11
Triples84
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around Complement component 1s to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Complement component 1s · EN edition · Analysis: TopicsToTalkAbout

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