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ACVRL1

Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene.

Pathology, Closely/family related kinases & Overview

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2.7.11.30
Aliases
ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, activin A receptor like type 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LCR, 3MY0, 4FAO
Band
12q13.13 · 15|15 F1
Bgee
right lung · upper lobe of left lung · tendon of biceps brachii · apex of heart · mucosa of transverse colon
BioGPS
More reference expression data

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Overview

Pathology

Closely/family related kinases

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Map overview Semantic statistics

ACVRL1

Nodes18
Edges17
Triples152
Avg. degree1.89
Density0.111111
Components1

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ACVRL1

Top relations

Gene ontology · 79
ACVRL1 → activin binding, activin receptor activity, type I, activin receptor complex, activin receptor signaling pathway, angiogenesis, artery development, ATP binding, blood circulation, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, blood vessel maturation, blood vessel morphogenesis, blood vessel remodeling, BMP receptor activity, BMP signaling pathway, cell surface, cellular response to BMP stimulus, cellular response to transforming growth factor beta stimulus, dendrite, dorsal aorta morphogenesis, endocardial cushion morphogenesis
Bgee · 19
ACVRL1 → apex of heart, canal of the cervix, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, extensor digitorum longus muscle, extraocular muscle, granulocyte, left lung, left lung lobe, left uterine tube, lower lobe of lung, mucosa of transverse colon, plantaris muscle, right lobe of thyroid gland, right lung, right lung lobe, subcutaneous adipose tissue, tendon of biceps brachii, upper lobe of left lung
RNA expression pattern · 19
ACVRL1 → apex of heart, canal of the cervix, cardiac muscle tissue of left ventricle, choroid plexus of fourth ventricle, extensor digitorum longus muscle, extraocular muscle, granulocyte, left lung, left lung lobe, left uterine tube, lower lobe of lung, mucosa of transverse colon, plantaris muscle, right lobe of thyroid gland, right lung, right lung lobe, subcutaneous adipose tissue, tendon of biceps brachii, upper lobe of left lung
related to External links · 6
ACVRL1 → GeneReviews/NCBI/NIH/UW, Hereditary Hemorrhagic TelangiectasiaHuman ACVRL1, Medicine, This, UCSC Genome Browser, United States National Library
related to Pathology · 3
ACVRL1 → Germline, Pulmonary, Rendu-Osler-Weber
Band · 2
ACVRL1 → 12q13.13, 15|15 F1
Chr. · 2
ACVRL1 → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
ACVRL1 → 101,043,217 bp, 51,923,361 bp
2.7.11.30 · 1
ACVRL1 → ↗
Aliases · 1
ACVRL1 → ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, activin A receptor like type 1

Important terminology Word statistics

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Important terminology

receptor gene bp kinase human type chr band activin chromosome 12 alk1 location also serine beta signaling pathway activity enzyme

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ACVRL12.7.11.301.00infobox
ACVRL1AliasesACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I, activin A receptor like type 11.00infobox
ACVRL1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LCR, 3MY0, 4FAO1.00infobox
ACVRL1Band12q13.131.00infobox
ACVRL1Band15|15 F11.00infobox
ACVRL1Bgeeright lung1.00infobox
ACVRL1Bgeeupper lobe of left lung1.00infobox
ACVRL1Bgeetendon of biceps brachii1.00infobox
ACVRL1Bgeeapex of heart1.00infobox
ACVRL1Bgeemucosa of transverse colon1.00infobox
ACVRL1Bgeeleft uterine tube1.00infobox
ACVRL1Bgeelower lobe of lung1.00infobox
ACVRL1Bgeeright lobe of thyroid gland1.00infobox
ACVRL1Bgeesubcutaneous adipose tissue1.00infobox
ACVRL1Bgeecanal of the cervix1.00infobox
ACVRL1Bgeegranulocyte1.00infobox
ACVRL1Bgeeleft lung1.00infobox
ACVRL1Bgeeright lung lobe1.00infobox
ACVRL1Bgeeleft lung lobe1.00infobox
ACVRL1Bgeecardiac muscle tissue of left ventricle1.00infobox
ACVRL1Bgeeextensor digitorum longus muscle1.00infobox
ACVRL1Bgeeextraocular muscle1.00infobox
ACVRL1Bgeeplantaris muscle1.00infobox
ACVRL1Bgeechoroid plexus of fourth ventricle1.00infobox
ACVRL1BioGPSMore reference expression data1.00infobox
ACVRL1Chr.Chromosome 12 (human)1.00infobox
ACVRL1Chr.Chromosome 15 (mouse)1.00infobox
ACVRL1DatabasesNCBI: entry; OMA: entry1.00infobox
ACVRL1End51,923,361 bp1.00infobox
ACVRL1End101,043,217 bp1.00infobox

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