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Human β-globin locus

The human β-globin locus is a cluster of genes located on chromosome 11. It is responsible for creating the β-chains found in hemoglobin. This cluster consists of 5 genes: ϵ, Gγ, Aγ, δ, and β genes, that respective order downstream. These genes are controlled by a locus control region (LCR) and are differentially expressed throughout development.…

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Human β-globin locus

Nodes62
Edges61
Triples2
Avg. degree1.97
Density0.032258
Components1

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Human β-globin locus

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Human β-globin locus → cluster of genes located on chromosome 11

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hemoglobin locus β-globin genes globin chains fetal mutations adult embryonic gene hba hbf oxygen sickle beta found cell production two

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Human β-globin locusis acluster of genes located on chromosome 110.90text
vaso-occlusive crisis which are common to the diseaseinstance ofDrugs and TreatmentsChronic blood transfusions is a common therapeutic option for treating sickle cell anemia by way of improving oxygen delivery and reducing complications0.80text

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