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Alpha-actinin-1

Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene.

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Aliases
ACTN1, BDPLT15, actinin alpha 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EYI, 2EYN, 2N8Z, 2N8Y
Band
14q24.1|14q22-q24 · 12 C3|12 36.49 cM
Bgee
saphenous vein · ascending aorta · right coronary artery · popliteal artery · tibial arteries
BioGPS
More reference expression data
Chr.
Chromosome 14 (human) · Chromosome 12 (mouse)

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Alpha-actinin-1

Nodes23
Edges22
Triples128
Avg. degree1.91
Density0.086957
Components1

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Alpha-actinin-1

Top relations

Gene ontology · 49
Alpha-actinin-1 → actin binding, actin crosslink formation, actin filament, actin filament binding, actin filament bundle assembly, actin filament network formation, actin filament organization, brush border, calcium ion binding, cell junction, cell projection, cell-cell junction, cytoplasm, cytoskeleton, cytosol, double-stranded RNA binding, extracellular exosome, extracellular region, extracellular space, fascia adherens
Bgee · 19
Alpha-actinin-1 → ascending aorta, ciliary body, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, gastric mucosa, granulocyte, Ileal epithelium, internal carotid artery, myometrium, popliteal artery, right coronary artery, saphenous vein, smooth muscle tissue, stria vascularis, stromal cell of endometrium, tibial arteries, tunica media of zone of aorta, vestibular membrane of cochlear duct
RNA expression pattern · 19
Alpha-actinin-1 → ascending aorta, ciliary body, Descending thoracic aorta, endothelial cell of lymphatic vessel, external carotid artery, gastric mucosa, granulocyte, Ileal epithelium, internal carotid artery, myometrium, popliteal artery, right coronary artery, saphenous vein, smooth muscle tissue, stria vascularis, stromal cell of endometrium, tibial arteries, tunica media of zone of aorta, vestibular membrane of cochlear duct
related to Interactions · 11
Alpha-actinin-1 → CDK5R1, CDK5R2, Collagen, GIPC1, N1, PDLIM1, Protein, PTPrho, PTPRT, SSX2IP, XVII
related to Function · 4
Alpha-actinin-1 → Alpha, F-actin, In, Z-disc
is a · 3
Alpha-actinin-1 → F-actin cross-linking protein, non-muscle cytoskeletal isoform found along microfilament bundles and adherens-type junctions, protein that in humans is encoded by the ACTN1 gene
Band · 2
Alpha-actinin-1 → 12 C3|12 36.49 cM, 14q24.1|14q22-q24
Chr. · 2
Alpha-actinin-1 → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
Alpha-actinin-1 → 68,979,440 bp, 80,307,145 bp
Aliases · 1
Alpha-actinin-1 → ACTN1, BDPLT15, actinin alpha 1

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Important terminology

bp gene human chr band actn1 alpha chromosome 14 protein location external actin mouse function search 979 440 end 68

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Alpha-actinin-1AliasesACTN1, BDPLT15, actinin alpha 11.00infobox
Alpha-actinin-1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EYI, 2EYN, 2N8Z, 2N8Y1.00infobox
Alpha-actinin-1Band14q24.1|14q22-q241.00infobox
Alpha-actinin-1Band12 C3|12 36.49 cM1.00infobox
Alpha-actinin-1Bgeesaphenous vein1.00infobox
Alpha-actinin-1Bgeeascending aorta1.00infobox
Alpha-actinin-1Bgeeright coronary artery1.00infobox
Alpha-actinin-1Bgeepopliteal artery1.00infobox
Alpha-actinin-1Bgeetibial arteries1.00infobox
Alpha-actinin-1Bgeestromal cell of endometrium1.00infobox
Alpha-actinin-1BgeeDescending thoracic aorta1.00infobox
Alpha-actinin-1Bgeesmooth muscle tissue1.00infobox
Alpha-actinin-1Bgeemyometrium1.00infobox
Alpha-actinin-1Bgeegastric mucosa1.00infobox
Alpha-actinin-1Bgeevestibular membrane of cochlear duct1.00infobox
Alpha-actinin-1BgeeIleal epithelium1.00infobox
Alpha-actinin-1Bgeegranulocyte1.00infobox
Alpha-actinin-1Bgeestria vascularis1.00infobox
Alpha-actinin-1Bgeetunica media of zone of aorta1.00infobox
Alpha-actinin-1Bgeeendothelial cell of lymphatic vessel1.00infobox
Alpha-actinin-1Bgeeexternal carotid artery1.00infobox
Alpha-actinin-1Bgeeinternal carotid artery1.00infobox
Alpha-actinin-1Bgeeciliary body1.00infobox
Alpha-actinin-1BioGPSMore reference expression data1.00infobox
Alpha-actinin-1Chr.Chromosome 14 (human)1.00infobox
Alpha-actinin-1Chr.Chromosome 12 (mouse)1.00infobox
Alpha-actinin-1DatabasesNCBI: entry; OMA: entry1.00infobox
Alpha-actinin-1End68,979,440 bp1.00infobox
Alpha-actinin-1End80,307,145 bp1.00infobox
Alpha-actinin-1EnsemblENSG000000721101.00infobox

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