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Actin, cytoplasmic 2, or gamma-actin is a protein that in humans is encoded by the ACTG1 gene. Gamma-actin is widely expressed in cellular cytoskeletons of many tissues; in adult striated muscle cells, gamma-actin is localized to Z-discs and costamere structures, which are responsible for force transduction and transmission in muscle cells. Mutations in…
The analysis highlights Clinical significance, Function and Structure as prominent areas in the source structure around Actin, cytoplasmic 2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Actin, cytoplasmic 2 shows recurring relationship patterns in the source. For example, Actin, cytoplasmic 2 → actin cytoskeleton, actin filament, ATP binding, blood microparticle, cell junction assembly, cytoplasm, cytoskeleton, cytosol, dense body, ephrin receptor signaling pathway, extracellular exosome, extracellular matrix, extracellular space, Fc-gamma receptor signaling pathway involved in phagocytosis, filamentous actin, focal adhesion, identical protein binding, membrane, membrane organization, myelin sheath Another extracted example is Actin, cytoplasmic 2 → amniotic fluid, blastocyst, dentate gyrus of hippocampal formation granule cell, embryo, epiblast, epithelium of nasopharynx, ganglionic eminence, granulocyte, mesencephalon, mucosa of ileum, neural tube, parietal pleura, pericardium, placenta, primary visual cortex, spinal ganglia, stomach, ventricular zone, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
actg1 gamma-actin actin human bp gene chr band muscle gamma myocytes protein identified patients chromosome 17 cytoskeleton location mutation cells
TTTA extracted 93 structured relationships around Actin, cytoplasmic 2. Examples in this analysis include Actin, cytoplasmic 2 → Aliases → ACTG1, ACT, ACTG, BRWS2, DFNA20, DFNA26, HEL-176, actin gamma 1 and Actin, cytoplasmic 2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5JLH. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Actin, cytoplasmic 2 | Aliases | ACTG1, ACT, ACTG, BRWS2, DFNA20, DFNA26, HEL-176, actin gamma 1 | 1.00 | infobox |
| Actin, cytoplasmic 2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5JLH | 1.00 | infobox |
| Actin, cytoplasmic 2 | Band | 17q25.3 | 1.00 | infobox |
| Actin, cytoplasmic 2 | Band | 11|11 E2 | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | mucosa of ileum | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | ventricular zone | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | amniotic fluid | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | embryo | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | ganglionic eminence | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | parietal pleura | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | visceral pleura | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | spinal ganglia | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | pericardium | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | granulocyte | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | neural tube | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | mesencephalon | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | placenta | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | primary visual cortex | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | epiblast | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | blastocyst | 1.00 | infobox |
| Actin, cytoplasmic 2 | Bgee | stomach | 1.00 | infobox |
| Actin, cytoplasmic 2 | BioGPS | More reference expression data | 1.00 | infobox |
| Actin, cytoplasmic 2 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| Actin, cytoplasmic 2 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| Actin, cytoplasmic 2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Actin, cytoplasmic 2 | End | 81,523,847 bp | 1.00 | infobox |
| Actin, cytoplasmic 2 | End | 120,239,368 bp | 1.00 | infobox |
| Actin, cytoplasmic 2 | Ensembl | ENSG00000184009 | 1.00 | infobox |
The concept neighborhoods around Actin, cytoplasmic 2 bring nearby vocabulary together. In this analysis, examples include Gamma, Gene and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Actin, cytoplasmic 2, one of the stronger structural bridges in this analysis connects Actin, cytoplasmic 2 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Actin, cytoplasmic 2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Actin, cytoplasmic 2 · EN edition · Analysis: TopicsToTalkAbout