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ZXDC

Zinc finger, X-linked, duplicated family member C (ZXDC) is a human CIITA-binding protein involved in the activation of major histocompatibility complex (MHC) class I and II. For binding to occur, ZXDC must form an oligomeric complex with another copy of itself or with ZXDA, a related protein. ZXDC is activated by sumoylation, a post-translational…

History, Structure & Overview

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Topic orientation

ZXDC at a glance

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Explore the main themes, entities and connections around ZXDC. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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History

1 related topic

Structure

2 related topics

Overview

8 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ZXDC, ZXDL, ZXD family zinc finger C
Band
3q21.3 · 6 D1|6
Bgee
gastrocnemius muscle · right lobe of liver · sural nerve · muscle of thigh · ganglionic eminence
BioGPS
n/a
Chr.
Chromosome 3 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

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Overview

History

Structure

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How this topic connects Entity context

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ZXDC

Top relations

Bgee · 19
ZXDC → aortic valve, ascending aorta, body of pancreas, decidua, ganglionic eminence, gastrocnemius muscle, Gonadal ridge, granulocyte, left ovary, muscle of thigh, Paneth cell, placenta, primary oocyte, retinal pigment epithelium, right lobe of liver, right ovary, right uterine tube, secondary oocyte, sural nerve
RNA expression pattern · 19
ZXDC → aortic valve, ascending aorta, body of pancreas, decidua, ganglionic eminence, gastrocnemius muscle, Gonadal ridge, granulocyte, left ovary, muscle of thigh, Paneth cell, placenta, primary oocyte, retinal pigment epithelium, right lobe of liver, right ovary, right uterine tube, secondary oocyte, sural nerve
Gene ontology · 13
ZXDC → C2H2 zinc finger domain binding, cellular component, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, LRR domain binding, metal ion binding, nucleic acid binding, nucleus, positive regulation of transcription, DNA-templated, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, transcription, DNA-templated
related to history · 9
ZXDC → C2H2, It, Later, They, This, When Sakaue, Xenopus, Xfin, ZXD Family Zinc Finger
related to Isolation · 5
ZXDC → But, Escherichia Coli, For, IMAC, ZXDC's
related to Function · 4
ZXDC → C2H2-type, This, ZXD, ZXD Family Zinc Finger
related to Structure · 4
ZXDC → C-terminus, C2H2-type, DNA, Near
related to Role in disease · 3
ZXDC → In, It, Numerous
Band · 2
ZXDC → 3q21.3, 6 D1|6
Chr. · 2
ZXDC → Chromosome 3 (human), Chromosome 6 (mouse)

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

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Important terminology

protein cancer zinc human finger bp expression family cell gene chr band chromosome binding function including may also tumor involved

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
ZXDCAliasesZXDC, ZXDL, ZXD family zinc finger C1.00infobox
ZXDCBand3q21.31.00infobox
ZXDCBand6 D1|61.00infobox
ZXDCBgeegastrocnemius muscle1.00infobox
ZXDCBgeeright lobe of liver1.00infobox
ZXDCBgeesural nerve1.00infobox
ZXDCBgeemuscle of thigh1.00infobox
ZXDCBgeeganglionic eminence1.00infobox
ZXDCBgeeright uterine tube1.00infobox
ZXDCBgeegranulocyte1.00infobox
ZXDCBgeebody of pancreas1.00infobox
ZXDCBgeeleft ovary1.00infobox
ZXDCBgeeright ovary1.00infobox
ZXDCBgeeascending aorta1.00infobox
ZXDCBgeeaortic valve1.00infobox
ZXDCBgeeplacenta1.00infobox
ZXDCBgeeprimary oocyte1.00infobox
ZXDCBgeedecidua1.00infobox
ZXDCBgeesecondary oocyte1.00infobox
ZXDCBgeeGonadal ridge1.00infobox
ZXDCBgeePaneth cell1.00infobox
ZXDCBgeeretinal pigment epithelium1.00infobox
ZXDCBioGPSn/a1.00infobox
ZXDCChr.Chromosome 3 (human)1.00infobox
ZXDCChr.Chromosome 6 (mouse)1.00infobox
ZXDCDatabasesNCBI: entry; OMA: entry1.00infobox
ZXDCEnd126,475,891 bp1.00infobox
ZXDCEnd90,380,472 bp1.00infobox
ZXDCEnsemblENSG000000704761.00infobox
ZXDCEntrez793641.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

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    Map overview Semantic statistics

    Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

    ZXDC

    Nodes15
    Edges14
    Triples102
    Avg. degree1.87
    Density0.133333
    Components1
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