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UBE2D2: Interactions, Function & Overview

Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the UBE2D2 gene.

Language: English [EN]
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UBE2D2 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around UBE2D2.

Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
95
Concept neighborhoods
9
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Function · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.23
2.3.2.24
Aliases
UBE2D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, ubiquitin conjugating enzyme E2 D2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UR6, 1W4U, 2CLW, 2ESK, 2ESO, 2ESP, 2ESQ, 3A33, 3JVZ, 3JW0, 3L1Y, 3TGD, 3ZNI, 4A49, 4A4B, 4A4C, 4AUQ, 4DDG,…
Band
5q31.2 · 18|18 B2
Bgee
ventricular zone · ganglionic eminence · right testis · left testis · right uterine tube

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How UBE2D2 connects Entity context

The extracted context around UBE2D2 shows recurring relationship patterns in the source. For example, UBE2D2 → ATP binding, cytosol, extracellular exosome, Fc-epsilon receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, nucleoplasm, nucleotide binding, protein autoubiquitination, protein binding, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein polyubiquitination, protein targeting to peroxisome, protein ubiquitination, protein-containing complex, regulation of transcription from RNA polymerase II promoter in response to hypoxia, stimulatory C-type lectin receptor signaling pathway, T cell receptor signaling pathway, transferase activity, TRIF-dependent toll-like receptor signaling pathway Another extracted example is UBE2D2 → dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, external carotid artery, ganglionic eminence, gastrocnemius muscle, Gonadal ridge, granulocyte, human fetus, left testis, mammillary body, median eminence, paraventricular nucleus of hypothalamus, pineal gland, rectum, right testis, right uterine tube, sperm, tibial arteries, ventral tegmental area, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

UBE2D2

Top relations

Gene ontology · 25
UBE2D2 → ATP binding, cytosol, extracellular exosome, Fc-epsilon receptor signaling pathway, MyD88-independent toll-like receptor signaling pathway, nucleoplasm, nucleotide binding, protein autoubiquitination, protein binding, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein polyubiquitination, protein targeting to peroxisome, protein ubiquitination, protein-containing complex, regulation of transcription from RNA polymerase II promoter in response to hypoxia, stimulatory C-type lectin receptor signaling pathway, T cell receptor signaling pathway, transferase activity, TRIF-dependent toll-like receptor signaling pathway
Bgee · 20
UBE2D2 → dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, external carotid artery, ganglionic eminence, gastrocnemius muscle, Gonadal ridge, granulocyte, human fetus, left testis, mammillary body, median eminence, paraventricular nucleus of hypothalamus, pineal gland, rectum, right testis, right uterine tube, sperm, tibial arteries, ventral tegmental area, ventricular zone
RNA expression pattern · 20
UBE2D2 → dorsal tegmental nucleus, dorsomedial hypothalamic nucleus, external carotid artery, ganglionic eminence, gastrocnemius muscle, Gonadal ridge, granulocyte, human fetus, left testis, mammillary body, median eminence, paraventricular nucleus of hypothalamus, pineal gland, rectum, right testis, right uterine tube, sperm, tibial arteries, ventral tegmental area, ventricular zone
related to Interactions · 4
UBE2D2 → Baculoviral IAP, NEDD4, PJA1, PJA2
Band · 2
UBE2D2 → 18|18 B2, 5q31.2
Chr. · 2
UBE2D2 → Chromosome 18 (mouse), Chromosome 5 (human)
End · 2
UBE2D2 → 139,628,434 bp, 35,942,547 bp
2.3.2.23 · 1
UBE2D2 → ↗
2.3.2.24 · 1
UBE2D2 → ↗
Aliases · 1
UBE2D2 → UBE2D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, ubiquitin conjugating enzyme E2 D2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band enzyme chromosome protein e2 location ubiquitin ubiquitin-conjugating mouse ubiquitin-protein ubiquitination d2 function conjugating external search

UBE2D2 relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around UBE2D2. Examples in this analysis include UBE2D2 → 2.3.2.23 → ↗ and UBE2D2 → Aliases → UBE2D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, ubiquitin conjugating enzyme E2 D2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
UBE2D22.3.2.231.00infobox
UBE2D22.3.2.241.00infobox
UBE2D2AliasesUBE2D2, E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH4, UBCH5B, ubiquitin conjugating enzyme E2 D21.00infobox
UBE2D2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UR6, 1W4U, 2CLW, 2ESK, 2ESO, 2ESP, 2ESQ, 3A33, 3JVZ, 3JW0, 3L1Y, 3TGD, 3ZNI, 4A49, 4A4B, 4A4C, 4AUQ, 4DDG,…1.00infobox
UBE2D2Band5q31.21.00infobox
UBE2D2Band18|18 B21.00infobox
UBE2D2Bgeeventricular zone1.00infobox
UBE2D2Bgeeganglionic eminence1.00infobox
UBE2D2Bgeeright testis1.00infobox
UBE2D2Bgeeleft testis1.00infobox
UBE2D2Bgeeright uterine tube1.00infobox
UBE2D2Bgeegastrocnemius muscle1.00infobox
UBE2D2Bgeegranulocyte1.00infobox
UBE2D2Bgeesperm1.00infobox
UBE2D2Bgeerectum1.00infobox
UBE2D2Bgeetibial arteries1.00infobox
UBE2D2BgeeGonadal ridge1.00infobox
UBE2D2Bgeeventral tegmental area1.00infobox
UBE2D2Bgeeexternal carotid artery1.00infobox
UBE2D2Bgeedorsomedial hypothalamic nucleus1.00infobox
UBE2D2Bgeepineal gland1.00infobox
UBE2D2Bgeemammillary body1.00infobox
UBE2D2Bgeeparaventricular nucleus of hypothalamus1.00infobox
UBE2D2Bgeehuman fetus1.00infobox
UBE2D2Bgeemedian eminence1.00infobox
UBE2D2Bgeedorsal tegmental nucleus1.00infobox
UBE2D2BioGPSMore reference expression data1.00infobox
UBE2D2Chr.Chromosome 5 (human)1.00infobox
UBE2D2Chr.Chromosome 18 (mouse)1.00infobox
UBE2D2DatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around UBE2D2 bring nearby vocabulary together. In this analysis, examples include Activity, Conjugating and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • UBE2D2
    • Activity
    • Conjugating
    • External
    • Function
    • Search
    • Ubiquitin
    • Gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • ube2d2
    • Activity
    • Conjugating
    • External
    • Function
    • Search
    • Ubiquitin
    • Gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • protein
    • Ube2d2
    • Ligase
    • Ubiquitin-protein
    • Ubiquitination
    • Cellular
    • Encoded
    • Gene
    • Humans
    • Targeting
    • Activity
    • Conjugating
    • End
  • gene
    • Location
    • Chromosome
    • Human
    • Ube2d2
    • Bp
    • Chr
    • Activity
    • Conjugating
    • End
    • External
    • Function
    • Mouse
  • protein p53
    • Ube2d2
    • Ligase
    • Ubiquitin-protein
    • Ubiquitination
    • Cellular
    • Encoded
    • Gene
    • Humans
    • Targeting
    • Activity
    • Conjugating
    • End
  • baculoviral iap repeat-containing protein 3
    • Ube2d2
    • Ligase
    • Ubiquitin-protein
    • Ubiquitination
    • Cellular
    • Encoded
    • Gene
    • Humans
    • Targeting
    • Activity
    • Conjugating
    • End
  • function
    • Activity
    • Conjugating
    • External
    • Search
    • Ubiquitin
    • Location
    • Cellular
    • Chromosome
    • Human
    • Interactions
    • Reading
    • References
  • interactions
    • Reading
    • References
    • Search
    • Ubiquitin
    • Location
    • Human
    • Ube2d2

Connections between topic areas Semantic bridges

For UBE2D2, one of the stronger structural bridges in this analysis connects UBE2D2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
UBE2D2Interactions · splits 7 ⟂ 7
UBE2D2Overview · splits 11 ⟂ 3
UBE2D2Function · splits 11 ⟂ 3

Map overview Semantic statistics

UBE2D2

Nodes14
Edges13
Triples95
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around UBE2D2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — UBE2D2 · EN edition · Analysis: TopicsToTalkAbout

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