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PJA2: Interactions & Overview

E3 ubiquitin-protein ligase Praja2 is an enzyme that in humans is encoded by the PJA2 gene.

Language: English [EN]
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PJA2 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around PJA2.

Related topics
4
Source areas
2
Connected nodes
6
Extracted relationships
92
Related term clusters
5
Bridge connections
6

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.27
↗
Aliases
PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2
Band
5q21.3 · 17|17 E1.1
Bgee
tail of epididymis · postcentral gyrus · frontal pole · Achilles tendon · Brodmann area 46
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 17 (mouse)

Start with your topic. Discover where to go next.

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PJA2
4Enzyme · Gene · Protein-protein interaction

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How PJA2 connects Entity context

The extracted context around PJA2 shows recurring relationship patterns in the source. For example, PJA2 → cell junction, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, Golgi apparatus, Golgi membrane, hippo signaling, inflammatory response, innate immune response, intermediate filament cytoskeleton, long-term memory, membrane, metal ion binding, plasma membrane, positive regulation of JNK cascade, positive regulation of p38MAPK cascade, positive regulation of toll-like receptor 2 signaling pathway, postsynaptic density, postsynaptic membrane, protein binding Another extracted example is PJA2 → Achilles tendon, Brodmann area 46, caput epididymis, dorsal striatum, facial motor nucleus, frontal pole, globus pallidus, inferior colliculi, interventricular septum, medial dorsal nucleus, nucleus accumbens, olfactory tubercle, orbitofrontal cortex, pons, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior vestibular nucleus, tail of epididymis, temporal lobe. Use these groups to spot repeated connection types before inspecting the individual relationships.

PJA2

Top relations

Gene ontology · 29
PJA2 → cell junction, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, Golgi apparatus, Golgi membrane, hippo signaling, inflammatory response, innate immune response, intermediate filament cytoskeleton, long-term memory, membrane, metal ion binding, plasma membrane, positive regulation of JNK cascade, positive regulation of p38MAPK cascade, positive regulation of toll-like receptor 2 signaling pathway, postsynaptic density, postsynaptic membrane, protein binding
Bgee · 20
PJA2 → Achilles tendon, Brodmann area 46, caput epididymis, dorsal striatum, facial motor nucleus, frontal pole, globus pallidus, inferior colliculi, interventricular septum, medial dorsal nucleus, nucleus accumbens, olfactory tubercle, orbitofrontal cortex, pons, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior vestibular nucleus, tail of epididymis, temporal lobe
RNA expression pattern · 20
PJA2 → Achilles tendon, Brodmann area 46, caput epididymis, dorsal striatum, facial motor nucleus, frontal pole, globus pallidus, inferior colliculi, interventricular septum, medial dorsal nucleus, nucleus accumbens, olfactory tubercle, orbitofrontal cortex, pons, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior vestibular nucleus, tail of epididymis, temporal lobe
Band · 2
PJA2 → 17|17 E1.1, 5q21.3
Chr. · 2
PJA2 → Chromosome 17 (mouse), Chromosome 5 (human)
End · 2
PJA2 → 109,409,974 bp, 64,638,911 bp
2.3.2.27 · 1
PJA2 → ↗
Aliases · 1
PJA2 → PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2
BioGPS · 1
PJA2 → More reference expression data
Databases · 1
PJA2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human band gene chromosome ligase location enzyme mouse ubiquitin-protein ubiquitin activity 409 974 end 109 17 e1 638

PJA2 relationships Subject–Predicate–Object triples

TTTA extracted 92 structured relationships around PJA2. Examples in this analysis include PJA2 → 2.3.2.27 → ↗ and PJA2 → Aliases → PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PJA22.3.2.27↗1.00infobox
PJA2AliasesPJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 21.00infobox
PJA2Band5q21.31.00infobox
PJA2Band17|17 E1.11.00infobox
PJA2Bgeetail of epididymis1.00infobox
PJA2Bgeepostcentral gyrus1.00infobox
PJA2Bgeefrontal pole1.00infobox
PJA2BgeeAchilles tendon1.00infobox
PJA2BgeeBrodmann area 461.00infobox
PJA2Bgeeprefrontal cortex1.00infobox
PJA2Bgeeorbitofrontal cortex1.00infobox
PJA2Bgeepons1.00infobox
PJA2Bgeecaput epididymis1.00infobox
PJA2Bgeesuperior vestibular nucleus1.00infobox
PJA2Bgeeinterventricular septum1.00infobox
PJA2Bgeemedial dorsal nucleus1.00infobox
PJA2Bgeedorsal striatum1.00infobox
PJA2Bgeetemporal lobe1.00infobox
PJA2Bgeeolfactory tubercle1.00infobox
PJA2Bgeeglobus pallidus1.00infobox
PJA2Bgeeinferior colliculi1.00infobox
PJA2Bgeefacial motor nucleus1.00infobox
PJA2BgeeRegion I of hippocampus proper1.00infobox
PJA2Bgeenucleus accumbens1.00infobox
PJA2BioGPSMore reference expression data1.00infobox
PJA2Chr.Chromosome 5 (human)1.00infobox
PJA2Chr.Chromosome 17 (mouse)1.00infobox
PJA2DatabasesNCBI: entry; OMA: entry1.00infobox
PJA2End109,409,974 bp1.00infobox
PJA2End64,638,911 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around PJA2 bring nearby vocabulary together. In this analysis, examples include Gene, Activity and Ubiquitin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Ligase
    • Location
    • Pja2
    • Chromosome
    • Human
    • Activity
    • Bp
    • Chr
    • E1
    • End
    • Mouse
    • Ubiquitin
  • PJA2
    • Gene
    • Activity
    • Ubiquitin
    • Ubiquitin-protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
    • Praja2
    • Reading
  • pja2
    • Gene
    • Activity
    • Ubiquitin
    • Ubiquitin-protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Interactions
    • Praja2
    • Reading
  • enzyme
    • Ligase
    • Pja2
    • Encoded
    • Gene
    • Humans
    • Interactions
    • Praja2
    • Reading
    • References
    • Activity
    • Ubiquitin
    • Ubiquitin-protein
  • interactions
    • Reading
    • References
    • Activity
    • Ubiquitin
    • Ligase
    • Location
    • Pja2
    • Chromosome
    • Human
    • Bp
    • Chr

Connections between topic areas Semantic bridges

For PJA2, one of the stronger structural bridges in this analysis connects PJA2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PJA2 — Overview · splits 4 ⟂ 3
PJA2 — Interactions · splits 4 ⟂ 3

Map overview Semantic statistics

PJA2

Nodes7
Edges6
Triples92
Avg. degree1.71
Density0.285714
Components1

Source & methodology

TTTA analyzes the structure around PJA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PJA2 · EN edition · Analysis: TopicsToTalkAbout

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