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E3 ubiquitin-protein ligase Praja2 is an enzyme that in humans is encoded by the PJA2 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around PJA2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around PJA2 shows recurring relationship patterns in the source. For example, PJA2 → cell junction, cytoplasm, endoplasmic reticulum, endoplasmic reticulum membrane, Golgi apparatus, Golgi membrane, hippo signaling, inflammatory response, innate immune response, intermediate filament cytoskeleton, long-term memory, membrane, metal ion binding, plasma membrane, positive regulation of JNK cascade, positive regulation of p38MAPK cascade, positive regulation of toll-like receptor 2 signaling pathway, postsynaptic density, postsynaptic membrane, protein binding Another extracted example is PJA2 → Achilles tendon, Brodmann area 46, caput epididymis, dorsal striatum, facial motor nucleus, frontal pole, globus pallidus, inferior colliculi, interventricular septum, medial dorsal nucleus, nucleus accumbens, olfactory tubercle, orbitofrontal cortex, pons, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior vestibular nucleus, tail of epididymis, temporal lobe. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp chr human band gene chromosome ligase location enzyme mouse ubiquitin-protein ubiquitin activity 409 974 end 109 17 e1 638
TTTA extracted 92 structured relationships around PJA2. Examples in this analysis include PJA2 → 2.3.2.27 → ↗ and PJA2 → Aliases → PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PJA2 | 2.3.2.27 | ↗ | 1.00 | infobox |
| PJA2 | Aliases | PJA2, Neurodap1, RNF131, praja ring finger ubiquitin ligase 2 | 1.00 | infobox |
| PJA2 | Band | 5q21.3 | 1.00 | infobox |
| PJA2 | Band | 17|17 E1.1 | 1.00 | infobox |
| PJA2 | Bgee | tail of epididymis | 1.00 | infobox |
| PJA2 | Bgee | postcentral gyrus | 1.00 | infobox |
| PJA2 | Bgee | frontal pole | 1.00 | infobox |
| PJA2 | Bgee | Achilles tendon | 1.00 | infobox |
| PJA2 | Bgee | Brodmann area 46 | 1.00 | infobox |
| PJA2 | Bgee | prefrontal cortex | 1.00 | infobox |
| PJA2 | Bgee | orbitofrontal cortex | 1.00 | infobox |
| PJA2 | Bgee | pons | 1.00 | infobox |
| PJA2 | Bgee | caput epididymis | 1.00 | infobox |
| PJA2 | Bgee | superior vestibular nucleus | 1.00 | infobox |
| PJA2 | Bgee | interventricular septum | 1.00 | infobox |
| PJA2 | Bgee | medial dorsal nucleus | 1.00 | infobox |
| PJA2 | Bgee | dorsal striatum | 1.00 | infobox |
| PJA2 | Bgee | temporal lobe | 1.00 | infobox |
| PJA2 | Bgee | olfactory tubercle | 1.00 | infobox |
| PJA2 | Bgee | globus pallidus | 1.00 | infobox |
| PJA2 | Bgee | inferior colliculi | 1.00 | infobox |
| PJA2 | Bgee | facial motor nucleus | 1.00 | infobox |
| PJA2 | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| PJA2 | Bgee | nucleus accumbens | 1.00 | infobox |
| PJA2 | BioGPS | More reference expression data | 1.00 | infobox |
| PJA2 | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| PJA2 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| PJA2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PJA2 | End | 109,409,974 bp | 1.00 | infobox |
| PJA2 | End | 64,638,911 bp | 1.00 | infobox |
The concept neighborhoods around PJA2 bring nearby vocabulary together. In this analysis, examples include Gene, Activity and Ubiquitin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PJA2, one of the stronger structural bridges in this analysis connects PJA2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PJA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PJA2 · EN edition · Analysis: TopicsToTalkAbout