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Tumor protein p63, typically referred to as p63, also known as transformation-related protein 63, is a protein that in humans is encoded by the TP63 (also known as the p63) gene.
The analysis highlights Function, Clinical significance and Diagnostic utility as prominent areas in the source structure around TP63.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TP63 shows recurring relationship patterns in the source. For example, TP63 → ageing, anatomical structure formation involved in morphogenesis, animal organ morphogenesis, apoptotic process, cell differentiation, cell population proliferation, cellular response to DNA damage stimulus, cellular response to UV, chromatin binding, chromatin remodeling, cloacal septation, cranial skeletal system development, cytoplasm, cytosol, damaged DNA binding, dendrite, developmental process, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA-binding transcription activator activity, RNA polymerase II-specific Another extracted example is TP63 → conjunctival fornix, corneal stroma, genital tubercle, gingival epithelium, gums, hair follicle, human penis, lip, molar, nipple, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of hip, skin of thigh, superior surface of tongue, transitional epithelium of urinary bladder, vulva. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
p63 gene human cell protein bp p53 also family tumor chr band transcription chromosome skin lip dna squamous cancer location
TTTA extracted 210 structured relationships around TP63. Examples in this analysis include TP63 → Aliases → TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L, tumor protein p63 and TP63 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4A9Z, 1RG6, 2RMN, 2Y9T, 2Y9U, 3QYM, 3QYN, 3US0, 3US1, 3US2, 3ZY0, 3ZY1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TP63 | Aliases | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L, tumor protein p63 | 1.00 | infobox |
| TP63 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4A9Z, 1RG6, 2RMN, 2Y9T, 2Y9U, 3QYM, 3QYN, 3US0, 3US1, 3US2, 3ZY0, 3ZY1 | 1.00 | infobox |
| TP63 | Band | 3q28 | 1.00 | infobox |
| TP63 | Band | 16 B1|16 17.37 cM | 1.00 | infobox |
| TP63 | Bgee | skin of thigh | 1.00 | infobox |
| TP63 | Bgee | skin of hip | 1.00 | infobox |
| TP63 | Bgee | skin of arm | 1.00 | infobox |
| TP63 | Bgee | human penis | 1.00 | infobox |
| TP63 | Bgee | hair follicle | 1.00 | infobox |
| TP63 | Bgee | vulva | 1.00 | infobox |
| TP63 | Bgee | gums | 1.00 | infobox |
| TP63 | Bgee | nipple | 1.00 | infobox |
| TP63 | Bgee | skin of abdomen | 1.00 | infobox |
| TP63 | Bgee | gingival epithelium | 1.00 | infobox |
| TP63 | Bgee | molar | 1.00 | infobox |
| TP63 | Bgee | skin of external ear | 1.00 | infobox |
| TP63 | Bgee | conjunctival fornix | 1.00 | infobox |
| TP63 | Bgee | skin of back | 1.00 | infobox |
| TP63 | Bgee | transitional epithelium of urinary bladder | 1.00 | infobox |
| TP63 | Bgee | corneal stroma | 1.00 | infobox |
| TP63 | Bgee | lip | 1.00 | infobox |
| TP63 | Bgee | superior surface of tongue | 1.00 | infobox |
| TP63 | Bgee | genital tubercle | 1.00 | infobox |
| TP63 | BioGPS | More reference expression data | 1.00 | infobox |
| TP63 | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| TP63 | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| TP63 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TP63 | End | 189,897,276 bp | 1.00 | infobox |
| TP63 | End | 25,710,852 bp | 1.00 | infobox |
| TP63 | Ensembl | ENSG00000073282 | 1.00 | infobox |
The concept neighborhoods around TP63 bring nearby vocabulary together. In this analysis, examples include Gene, Tumor and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TP63, one of the stronger structural bridges in this analysis connects TP63 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TP63 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Diagnostic utility, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TP63 · EN edition · Analysis: TopicsToTalkAbout