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Telomeric repeat-binding factor 1

Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene.

Interactions, Subcellular distribution & Protein

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Interactions

12 related topics

Subcellular distribution

7 related topics

Protein

3 related topics

Function

3 related topics

Key facts & relationships

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Aliases
TERF1, PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1, telomeric repeat binding factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BA5, 1ITY, 1IV6, 1W0T, 3BQO, 3L82, 5HKP
Band
8q21.11 · 1 A3|1 4.88 cM
Bgee
buccal mucosa cell · sural nerve · spinal ganglia · tail of epididymis · pars reticulata
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 1 (mouse)

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Overview

Protein

Subcellular distribution

Function

Biological processes

Interactions

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Telomeric repeat-binding factor 1

Nodes36
Edges35
Triples149
Avg. degree1.94
Density0.055556
Components1

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Telomeric repeat-binding factor 1

Top relations

Gene ontology · 54
Telomeric repeat-binding factor 1 → ankyrin repeat binding, cell cycle, cell division, chromosome, cytoplasm, cytoskeleton, DNA binding, DNA binding, bending, DNA-binding transcription factor activity, RNA polymerase II-specific, double-stranded telomeric DNA binding, fibrillar center, G-rich strand telomeric DNA binding, G2/M transition of mitotic cell cycle, meiotic telomere clustering, microtubule binding, mitotic spindle assembly checkpoint signaling, negative regulation of DNA replication, negative regulation of establishment of protein localization to telomere, negative regulation of establishment of protein-containing complex localization to telomere, negative regulation of establishment of RNA localization to telomere
Bgee · 20
Telomeric repeat-binding factor 1 → blastocyst, buccal mucosa cell, embryo, epiblast, genital tubercle, germinal epithelium, maxillary prominence, morula, pars compacta, pars reticulata, primary oocyte, seminal vesicula, spinal ganglia, sural nerve, tail of embryo, tail of epididymis, trigeminal ganglion, ventricular zone, yolk sac, zygote
RNA expression pattern · 20
Telomeric repeat-binding factor 1 → blastocyst, buccal mucosa cell, embryo, epiblast, genital tubercle, germinal epithelium, maxillary prominence, morula, pars compacta, pars reticulata, primary oocyte, seminal vesicula, spinal ganglia, sural nerve, tail of embryo, tail of epididymis, trigeminal ganglion, ventricular zone, yolk sac, zygote
related to Interactions · 18
Telomeric repeat-binding factor 1 → Abelson, ABL, Ataxia, ATM, In, MAPRE2, Microtubule-associated, NME1, PINX1, RP/EB, Sal-like1- Drosophila, SALL1, Tankyrase, TERF1, TERF1-interacting, The TERF1, TINF2, TNKS2
related to Biological processes · 11
Telomeric repeat-binding factor 1 → Additionally, Christopher, DNA, In, It, Kaplan, Other, TERF, The, These, This
Band · 2
Telomeric repeat-binding factor 1 → 1 A3|1 4.88 cM, 8q21.11
Chr. · 2
Telomeric repeat-binding factor 1 → Chromosome 1 (mouse), Chromosome 8 (human)
End · 2
Telomeric repeat-binding factor 1 → 15,914,276 bp, 73,048,123 bp
Aliases · 1
Telomeric repeat-binding factor 1 → TERF1, PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1, telomeric repeat binding factor 1
Available structures · 1
Telomeric repeat-binding factor 1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BA5, 1ITY, 1IV6, 1W0T, 3BQO, 3L82, 5HKP

Important terminology Word statistics

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Important terminology

protein telomere gene telomeric telomerase chromosome factor terf1 human bp binding trf1 process chromosomes dna chr band biological ends regulation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Telomeric repeat-binding factor 1AliasesTERF1, PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1, telomeric repeat binding factor 11.00infobox
Telomeric repeat-binding factor 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BA5, 1ITY, 1IV6, 1W0T, 3BQO, 3L82, 5HKP1.00infobox
Telomeric repeat-binding factor 1Band8q21.111.00infobox
Telomeric repeat-binding factor 1Band1 A3|1 4.88 cM1.00infobox
Telomeric repeat-binding factor 1Bgeebuccal mucosa cell1.00infobox
Telomeric repeat-binding factor 1Bgeesural nerve1.00infobox
Telomeric repeat-binding factor 1Bgeespinal ganglia1.00infobox
Telomeric repeat-binding factor 1Bgeetail of epididymis1.00infobox
Telomeric repeat-binding factor 1Bgeepars reticulata1.00infobox
Telomeric repeat-binding factor 1Bgeegerminal epithelium1.00infobox
Telomeric repeat-binding factor 1Bgeeseminal vesicula1.00infobox
Telomeric repeat-binding factor 1Bgeeventricular zone1.00infobox
Telomeric repeat-binding factor 1Bgeetrigeminal ganglion1.00infobox
Telomeric repeat-binding factor 1Bgeepars compacta1.00infobox
Telomeric repeat-binding factor 1Bgeeyolk sac1.00infobox
Telomeric repeat-binding factor 1Bgeetail of embryo1.00infobox
Telomeric repeat-binding factor 1Bgeezygote1.00infobox
Telomeric repeat-binding factor 1Bgeemorula1.00infobox
Telomeric repeat-binding factor 1Bgeeepiblast1.00infobox
Telomeric repeat-binding factor 1Bgeeembryo1.00infobox
Telomeric repeat-binding factor 1Bgeegenital tubercle1.00infobox
Telomeric repeat-binding factor 1Bgeeblastocyst1.00infobox
Telomeric repeat-binding factor 1Bgeemaxillary prominence1.00infobox
Telomeric repeat-binding factor 1Bgeeprimary oocyte1.00infobox
Telomeric repeat-binding factor 1BioGPSn/a1.00infobox
Telomeric repeat-binding factor 1Chr.Chromosome 8 (human)1.00infobox
Telomeric repeat-binding factor 1Chr.Chromosome 1 (mouse)1.00infobox
Telomeric repeat-binding factor 1DatabasesNCBI: entry; OMA: entry1.00infobox
Telomeric repeat-binding factor 1End73,048,123 bp1.00infobox
Telomeric repeat-binding factor 1End15,914,276 bp1.00infobox

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