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Adverse drug reaction

An adverse drug reaction (ADR) is an unintended medical event, which can potentially be associated with taking a medication. It can be disadvantageous or beneficial for the patient. ADRs may occur following a single dose or prolonged administration of a drug or may result from the combination of two or more drugs. The meaning of this term differs from…

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Adverse drug reaction

Nodes92
Edges91
Triples40
Avg. degree1.98
Density0.021739
Components1

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Adverse drug reaction

Top relations

related to Assessing causality · 14
Adverse drug reaction → ADR, ADRs, An ADR, Assigning, Both, Causality, Each, Even, Naranjo, Psychiatric ADRs, The, There, Venulet, WHO
related to Further reading · 12
Adverse drug reaction → Advanced Pharmaceutical Technology, Babu SC, Incidence, ISSN, Jain SK, Journal, Medknow, PMC, PMID, Research, Srikanth BA, Yadav HN

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Important terminology

drug adverse reactions effects medications metabolism events may type event adrs medication reaction drugs one due used adr administration harm

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
isoniazidinstance ofmay affect metabolism of drugs such as succinylcholine.Phase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect t…0.80text
hydralazineinstance ofmay affect metabolism of drugs such as succinylcholine.Phase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect t…0.80text
and procainamide.Inheriting abnormal thiopurine S-methyltransferase may affect the metabolism of the thiopurine drugs mercaptopurineinstance ofmay affect metabolism of drugs such as succinylcholine.Phase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect t…0.80text
azathioprine.Protein bindingProtein binding interactions are usually transientinstance ofmay affect metabolism of drugs such as succinylcholine.Phase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect t…0.80text
mild until a new steady state is achievedinstance ofmay affect metabolism of drugs such as succinylcholine.Phase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect t…0.80text
the antibiotic clarithromycininstance ofinhibitor0.80text
as well as another medication metabolized by CYP3A4 such as the anticoagulant apixabaninstance ofinhibitor0.80text
which results in elevated blood concentrations of apixabaninstance ofinhibitor0.80text
greater risk of serious bleedsinstance ofinhibitor0.80text
succinylcholineinstance ofmay affect metabolism of drugs0.80text
isoniazidinstance ofPhase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect the metabolism of drugs0.80text
hydralazineinstance ofPhase II reactionsInheriting abnormal N-acetyltransferase which conjugated some drugs to facilitate excretion may affect the metabolism of drugs0.80text

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