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Hydralazine: Applications, Research, Art & Standards

Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure. This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. It has been found to be particularly useful in heart failure, together with isosorbide dinitrate, for treatment of people of…

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Hydralazine topic overview

The analysis highlights Applications, Research, Art and Standards as prominent areas in the source structure around Hydralazine.

Related topics
64
Source areas
7
Connected nodes
71
Extracted relationships
43
Related term clusters
26
Bridge connections
71

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Medical use · 19 topics
Overview · 17 topics
Interactions · 11 topics
Mechanism of action · 8 topics
Adverse effects · 6 topics
Research · 2 topics
Chemistry · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C02DB02 (WHO)
Bioavailability
26–50%
CAS Number
86-54-4 Y
ChEBI
CHEBI:5775 Y

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical use

Adverse effects

Interactions

Mechanism of action

Chemistry

Research

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Hydralazine connects Entity context

The extracted context around Hydralazine shows recurring relationship patterns in the source. For example, Hydralazine → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only Another extracted example is Hydralazine → C-5968, Ciba, Ciba's, FDA. Use these groups to spot repeated connection types before inspecting the individual relationships.

Hydralazine

Top relations

Legal status · 4
Hydralazine → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to history · 4
Hydralazine → C-5968, Ciba, Ciba's, FDA
related to Mechanism of action · 3
Hydralazine → Ca2, Metabolic, N-acetyl
related to Interactions · 2
Hydralazine → ACE, Tricyclic
3D model (JSmol) · 1
Hydralazine → Interactive image
AHFS/Drugs.com · 1
Hydralazine → Monograph
ATC code · 1
Hydralazine → C02DB02 (WHO)
Bioavailability · 1
Hydralazine → 26–50%
CAS Number · 1
Hydralazine → 86-54-4 Y
ChEBI · 1
Hydralazine → CHEBI:5775 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

heart effects blood used treatment may pressure failure people drugs treat side include disease pregnancy mouth action drug also muscle

Hydralazine relationships Subject–Predicate–Object triples

TTTA extracted 43 structured relationships around Hydralazine. Examples in this analysis include Hydralazine → 3D model (JSmol) → Interactive image and Hydralazine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Hydralazine3D model (JSmol)Interactive image1.00infobox
HydralazineAHFS/Drugs.comMonograph1.00infobox
HydralazineATC codeC02DB02 (WHO)1.00infobox
HydralazineBioavailability26–50%1.00infobox
HydralazineCAS Number86-54-4 Y1.00infobox
HydralazineChEBICHEBI:5775 Y1.00infobox
HydralazineChEMBLChEMBL276832 Y1.00infobox
HydralazineChemSpider3511 Y1.00infobox
HydralazineCompTox Dashboard (EPA)DTXSID40231291.00infobox
HydralazineDrugBankDB01275 Y1.00infobox
HydralazineDuration of action2–6 hours1.00infobox
HydralazineECHA InfoCard100.001.5281.00infobox
HydralazineElimination half-life2–8 hours, 7–16 hours (renal impairment)1.00infobox
HydralazineExcretionUrine1.00infobox
HydralazineFormulaC8H8N41.00infobox
HydralazineIUPHAR/BPS73261.00infobox
HydralazineKEGGD08044 Y1.00infobox
HydralazineLegal statusAU: S4 (Prescription only)1.00infobox
HydralazineLegal statusCA: ℞-only1.00infobox
HydralazineLegal statusUK: POM (Prescription only)1.00infobox
HydralazineLegal statusUS: ℞-only1.00infobox
HydralazineLicense dataUS DailyMed: Hydralazine1.00infobox
HydralazineMedlinePlusa6822461.00infobox
HydralazineMetabolismLiver1.00infobox
HydralazineMolar mass160.180 g·mol−11.00infobox
HydralazineOnset of action5–30 minutes1.00infobox
HydralazinePregnancy categoryAU: C1.00infobox
HydralazineProtein binding85–90%1.00infobox
HydralazinePubChem CID36371.00infobox
HydralazineRoutes of administrationBy mouth, intravenous1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Hydralazine bring nearby vocabulary together. In this analysis, examples include Drugs, Used and Treat. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Hydralazine
    • Drugs
    • Used
    • Treat
    • Effects
    • Heart
    • Hypertension
    • Also
    • Drug
    • Treatment
    • Blood
    • May
    • Action
  • hydralazine
    • Drugs
    • Used
    • Treat
    • Effects
    • Heart
    • Hypertension
    • Also
    • Drug
    • Treatment
    • Blood
    • May
    • Action
  • heart failure
    • Failure
    • Heart
    • People
    • Used
    • Dinitrate
    • Isosorbide
    • Treatment
    • Name
    • Others
    • Effects
    • Disease
    • High
  • high blood pressure in pregnancy
    • Pressure
    • Hypertension
    • Blood
    • High
    • Medication
    • Name
    • Others
    • Used
    • Action
    • Hours
    • Minutes
    • Pregnancy
  • fast heart rate
    • Failure
    • People
    • Used
    • Name
    • Others
    • Effects
    • Dinitrate
    • Disease
    • Isosorbide
    • Hydralazine
    • Treatment
    • May
  • rheumatic heart disease
    • Recommended
    • Failure
    • People
    • Used
    • Name
    • Others
    • Effects
    • Dinitrate
    • Disease
    • Heart
    • Increase
    • Isosorbide
  • congestive heart failure
    • Failure
    • Heart
    • People
    • Used
    • Dinitrate
    • Isosorbide
    • Treatment
    • Name
    • Others
    • Effects
    • Disease
    • High
  • isosorbide dinitrate/hydralazine
    • Isosorbide
    • Failure
    • Treatment
    • Drugs
    • Used
    • Treat
    • Heart
    • Effects
    • Drug
    • Hypertension
    • People
    • Also

Connections between topic areas Semantic bridges

For Hydralazine, one of the stronger structural bridges in this analysis connects Hydralazine with Medical use. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Hydralazine — Medical use · splits 52 ⟂ 20
Hydralazine — Overview · splits 54 ⟂ 18
Hydralazine — Interactions · splits 60 ⟂ 12
Hydralazine — Mechanism of action · splits 63 ⟂ 9
Hydralazine — Adverse effects · splits 65 ⟂ 7
Hydralazine — Research · splits 69 ⟂ 3

Map overview Semantic statistics

Hydralazine

Nodes72
Edges71
Triples43
Avg. degree1.97
Density0.027778
Components1

Source & methodology

TTTA analyzes the structure around Hydralazine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Research, Art & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Hydralazine · EN edition · Analysis: TopicsToTalkAbout

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