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Hydralazine

Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure. This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms. It has been found to be particularly useful in heart failure, together with isosorbide dinitrate, for treatment of people of…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C02DB02 (WHO)
Bioavailability
26–50%
CAS Number
86-54-4 Y
ChEBI
CHEBI:5775 Y

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Overview

Medical use

Adverse effects

Interactions

Mechanism of action

Chemistry

Research

Advanced semantic analysis

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Map overview Semantic statistics

Hydralazine

Nodes73
Edges72
Triples50
Avg. degree1.97
Density0.027397
Components1

How this topic connects Entity context

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Hydralazine

Top relations

related to history · 6
Hydralazine → C-5968, Ciba, Ciba's, FDA, It, The
related to Mechanism of action · 5
Hydralazine → By, Ca2, Metabolic, N-acetyl, The
Legal status · 4
Hydralazine → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
has effect · 2
Hydralazine → Prolonged, Very
related to Interactions · 2
Hydralazine → ACE, Tricyclic
related to Medical use · 2
Hydralazine → The, To
3D model (JSmol) · 1
Hydralazine → Interactive image
AHFS/Drugs.com · 1
Hydralazine → Monograph
ATC code · 1
Hydralazine → C02DB02 (WHO)
Bioavailability · 1
Hydralazine → 26–50%

Important terminology Word statistics

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Important terminology

heart effects blood used treatment may pressure failure people drugs treat side include disease pregnancy mouth action drug also muscle

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Hydralazine3D model (JSmol)Interactive image1.00infobox
HydralazineAHFS/Drugs.comMonograph1.00infobox
HydralazineATC codeC02DB02 (WHO)1.00infobox
HydralazineBioavailability26–50%1.00infobox
HydralazineCAS Number86-54-4 Y1.00infobox
HydralazineChEBICHEBI:5775 Y1.00infobox
HydralazineChEMBLChEMBL276832 Y1.00infobox
HydralazineChemSpider3511 Y1.00infobox
HydralazineCompTox Dashboard (EPA)DTXSID40231291.00infobox
HydralazineDrugBankDB01275 Y1.00infobox
HydralazineDuration of action2–6 hours1.00infobox
HydralazineECHA InfoCard100.001.5281.00infobox
HydralazineElimination half-life2–8 hours, 7–16 hours (renal impairment)1.00infobox
HydralazineExcretionUrine1.00infobox
HydralazineFormulaC8H8N41.00infobox
HydralazineIUPHAR/BPS73261.00infobox
HydralazineKEGGD08044 Y1.00infobox
HydralazineLegal statusAU: S4 (Prescription only)1.00infobox
HydralazineLegal statusCA: ℞-only1.00infobox
HydralazineLegal statusUK: POM (Prescription only)1.00infobox
HydralazineLegal statusUS: ℞-only1.00infobox
HydralazineLicense dataUS DailyMed: Hydralazine1.00infobox
HydralazineMedlinePlusa6822461.00infobox
HydralazineMetabolismLiver1.00infobox
HydralazineMolar mass160.180 g·mol−11.00infobox
HydralazineOnset of action5–30 minutes1.00infobox
HydralazinePregnancy categoryAU: C1.00infobox
HydralazineProtein binding85–90%1.00infobox
HydralazinePubChem CID36371.00infobox
HydralazineRoutes of administrationBy mouth, intravenous1.00infobox

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